Frankfurt Frankfurt 2011
361 pages
English

Frankfurt Frankfurt 2011

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361 pages
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Prudent Practices in the Laboratory: Handling and
Management of Chemical Hazards, Updated Version
The Committee on Prudent Practices in the Laboratory:
An Update; National Research Council

ISBN: 0-309-13865-5, 360 pages, 8.5 x 11, (2011)

This PDF is available from the National Academies Press at:
http://www.nap.edu/catalog/12654.html





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Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards, Updated Version
http://www.nap.edu/catalog/12654.html
UPDATED VERSION
Committee on Prudent Practices in the Laboratory: An Update
Board on Chemical Sciences and Technology
Division on Earth and Life Studies
THE NATIONAL ACADEMIES PRESS
Washington, D.C.
www.nap.edu
Copyright © National Academy of Sciences. All rights reserved.Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards, Updated Version
http://www.nap.edu/catalog/12654.html
THE NATIONAL ACADEMIES PRESS • 500 Fifth Street, N.W. • Washington, DC 20001
NOTICE: The project that is the subject of this report was approved by the Governing Board of the
National Research Council, whose members are drawn from the councils of the National Academy of
Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the
committee responsible for the report were chosen for their special competences and with regard for
appropriate balance.
This study was supported by the U.S. Department of Energy under grant number DE-FG02-08ER15932;
the National Institutes of Health under contract number N01-OD-4-2139, TO #200; and the National
Science Foundation under grant number CHE-0740356. Additional support was received from Air
Products and Chemicals, Inc.; the American Chemical Society; E. I. du Pont de Nemours and Company;
Eastman Chemical Company; the Howard Hughes Medical Institute; and PPG Industries.
Any opinions, fndings, conclusions, or recommendations expressed in this publication are those of
the authors and do not necessarily refect the views of the organizations or agencies that provided
support for the project.
Library of Congress Cataloging-in-Publication Data
Prudent practices in the laboratory : handling and management of chemical hazards / Committee on
Prudent Practices in the Laboratory, Board on Chemical Sciences and Technology, Division on Earth
and Life Studies. — Updated ed.
p. cm.
Includes bibliographical references and index.
ISBN-13: 978-0-309-13864-2 (hardback)
ISBN-10: 0-309-13864-7 (hardback)
ISBN-13: 978-0-309-13865-9 (pdf)
ISBN-10: 0-309-13865-5 (pdf)
1. Hazardous substances. 2. Chemicals—Safety measures. 3. Hazardous wastes. I. National
Research Council (U.S.). Committee on Prudent Practices in the Laboratory.
T55.3.H3P78 2011
660’.2804—dc22
2010047731
Additional copies of this report are available from The National Academies Press, 500 Fifth Street, N.W.,
Lockbox 285, Washington, DC 20055; (800) 624-6242 or (202) 334-3313 (in the Washington metropolitan
area); Internet, http://www.nap.edu.
Copyright 2011 by the National Academy of Sciences. All rights reserved.
Printed in the United States of America
Copyright © National Academy of Sciences. All rights reserved.Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards, Updated Version
http://www.nap.edu/catalog/12654.html
The National Academy of Sciences is a private, nonproft, self-perpetuating society of
distinguished scholars engaged in scientifc and engineering research, dedicated to the
furtherance of science and technology and to their use for the general welfare. Upon the
authority of the charter granted to it by the Congress in 1863, the Academy has a mandate
that requires it to advise the federal government on scientifc and technical matters. Dr.
Ralph J. Cicerone is president of the National Academy of Sciences.
The National Academy of Engineering was established in 1964, under the charter of the
National Academy of Sciences, as a parallel organization of outstanding engineers. It is
autonomous in its administration and in the selection of its members, sharing with the
National Academy of Sciences the responsibility for advising the federal government. The
National Academy of Engineering also sponsors engineering programs aimed at meeting
national needs, encourages education and research, and recognizes the superior achieve-
ments of engineers. Dr. Charles M. Vest is president of the National Academy of Engineering.
The Institute of Medicine was established in 1970 by the National Academy of Sciences to
secure the services of eminent members of appropriate professions in the examination of
policy matters pertaining to the health of the public. The Institute acts under the responsibil-
ity given to the National Academy of Sciences by its congressional charter to be an adviser
to the federal government and, upon its own initiative, to identify issues of medical care,
research, and education. Dr. Harvey V. Fineberg is president of the Institute of Medicine.
The National Research Council was organized by the National Academy of Sciences in 1916
to associate the broad community of science and technology with the Academy’s purposes
of furthering knowledge and advising the federal government. Functioning in accordance
with general policies determined by the Academy, the Council has become the principal
operating agency of both the National Academy of Sciences and the National Academy
of Engineering in providing services to the government, the public, and the scientifc and
engineering communities. The Council is administered jointly by both Academies and the
Institute of Medicine. Dr. Ralph J. Cicerone and Dr. Charles M. Vest are chair and vice chair,
respectively, of the National Research Council.
www.national-academies.org
Copyright © National Academy of Sciences. All rights reserved.Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards, Updated Version
http://www.nap.edu/catalog/12654.html
Copyright © National Academy of Sciences. All rights reserved.Prudent Practices in the Laboratory: Handling and Management of Chemical Hazards, Updated Version
http://www.nap.edu/catalog/12654.html
COMMITTEE ON PRUDENT PRACTICES IN
THE LABORATORY: AN UPDATE
Co-Chairs
William F. Carroll, Jr., Occidental Chemical Corporation, Dallas, Texas
BarBara l. Foster, West Virginia University, Morgantown
MeMbers
W. emmett Barkley, Proven Practices, LLC, Bethesda, Maryland
susan H. Cook, Washington University, St. Louis, Missouri
kennetH P. Fivizzani, Nalco Company, Naperville, Illinois
roBin izzo, Princeton University, Princeton, New Jersey
kennetH a. JaCoBson, National Institutes of Health, Bethesda, Maryland
karen mauPins, Eli Lilly & Company Drug Discovery, Indianapolis, Indiana
kennetH moloy, E. I. du Pont de Nemours & Company, Wilmington, Delaware
randall B. ogle, Oak Ridge National Laboratory, Oak Ridge, Tennessee
JoHn Palassis, U.S. Department of Health and Human Services, Cincinnati, Ohio
russell W. PHiFer, WC Environmental, LLC, West Chester, Pennsylvania
Peter a. reinHardt, Yale University, New Haven, Connecticut
levi t. tHomPson, University of Michigan, Ann Arbor, Michigan
leyte WinField, Spelman College, Atlanta, Georgia
NatioNal researCh CouNCil staff
dorotHy zolandz, Director
andreW CroWtHer, Postdoctoral Fellow
kevin kuHn, Mirzayan Fellow
katHryn HugHes, Responsible Staff Offcer
tina m. masCiangioli, Senior Program Offcer
kela masters, Senior Program Assistant (through October 2008)
JessiCa Pullen, Administrative Coordinator
sHeena siddiqui, Research Associate
sally stanField, Editor
lynelle vidale, Program Assistant
v
Copyright © National Academy of Sciences. All rights reserved.Prudent Practices in the Laboratory: Hand

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