Untitled - UFDC Image Array 2 - University of Florida

Description

http://stemcells.nih.gov/research/registry/. ...... for compiling and maintaining project documentation and reports. ...... EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.) ...... 1990-1994 Echols Scholar Program, University of Virginia ...

Informations

• Publié par: paul.vallen
• Nombre de lectures: 39
• Langue: English
• Poids de l'ouvrage: 3 Mo

Extrait

Form Approved Through 11/30/2010

Department of Health and Human Services Public Health Services Grant Application Do not exceed character length restrictions indicated.

OMB No. 0925-0001 LEAVE BLANK—FOR PHS USE ONLY. Type Activity Number Review Group Formerly

Council/Board (Month, Year)

Date Received

1. TITLE OF PROJECT(Do not exceed 81 characters, including spaces and punctuation.) VIVO: Enabling National Networking of Scientists 2. RESPONSE TO SPECIFIC REQUEST FOR APPLICATIONS OR PROGRAM ANNOUNCEMENT OR SOLICITATIONNO YES (If “Yes,” state number and title) RFA-RR-09-00 overy Act 2009 Limited Competiti Number: 9Rec on: Enabling National Networking of Scientists Title: and Resource Discovery (U24) 3. PROGRAM DIRECTOR/PRINCIPAL INVESTIGATOR New Investigator No Yes 3a. NAME (Last, first, middle) 3b. DEGREE(S) 3h. eRA Commons User Name Conlon, MichaelBAM. StatPhDMCONLON

3c. POSITION TITLE Interim Director of Biomedical Informatics 3e. DEPARTMENT, SERVICE, LABORATORY, OR EQUIVALENT Biomedical Informatics 3f. MAJOR SUBDIVISION College of Medicine 3g. TELEPHONE AND FAX(Area code, number and extension) TEL: [phone] FAX: [phone]

3d. MAILING ADDRESS(Street, city, state, zip code) 105 NW 16 Street, Room 334 PO Box 14823 Gainesville, FL 32604

E-MAIL ADDRESS: [e-mail]

4. HUMAN SUBJECTS RESEARCH 4a. Research Exempt If “Yes,” Exemption No.  No Yes No Yes 4b. Federal-Wide Assurance No. 4c. Clinical Trial4d. NIH-defined Phase III Clinical Trial  No YesNo Yes 5. VERTEBRATE ANIMALS No Yes 5a. Animal Welfare Assurance No. 6. DATES OF PROPOSED PERIOD OF 7. COSTS REQUESTED FOR INITIAL 8. COSTS REQUESTED FOR PROPOSED  SUPPORT(month,day,year—MM/DD/YY) BUDGET PERIOD PERIOD OF SUPPORT From Through 7a. Direct Costs ($) 7b. Total Costs ($) 8a. Direct Costs ($) 8b. Total Costs ($) 9/1/2009 8/31/2011 $4,001,591 $6,071,796 $8,072,119 $12,265,886 9. APPLICANT ORGANIZATION 10. TYPE OF ORGANIZATION Name University of Florida →ocal Fed Public: eral State L

Address

University of Florida Board of Trustees Division of Sponsored Research 219 Grinter Hall P.O. Box 115500 Gainesville, Florida 32611-5500

12. ADMINISTRATIVE OFFICIAL TO BE NOTIFIED IF AWARD IS MADE Name Title

Address

Private:→

 Private Nonprofit

For-profit:→Small Business General  Woman-owned Socially and Economically Disadvantaged

11. ENTITY IDENTIFICATION NUMBER 59-6002052 Cong. District DUNS NO. 969663814 FL-006 13. OFFICIAL SIGNING FOR APPLICANT ORGANIZATION Name Brian Prindle

Title Associate Director for Sponsored Research Address P.O. Box 115500 Gainesville, Florida 32611-5500

Tel: FAX: Tel: [phone] FAX: [phone] E-Mail: E-Mail: [e-mail] 14. APPLICANT ORGANIZATION CERTIFICATION AND ACCEPTANCE: I certify that DATESIGNATURE OF OFFICIAL NAMED IN 13. the statements herein are true, complete and accurate to the best of my knowledge, and (In ink. “Per” signature not acceptable.) accept the obligation to comply with Public Health Services terms and conditions if a grant is awarded as a result of this application. I am aware that any false, fictitious, or fraudulent statements or claims may subject me to criminal, civil, or administrative penalties. PHS 398 (Rev. 11/07) Face PageForm Page 1

Program Director/Principal Investigator (Last, First, Middle):

Conlon, Michael

PROJECT SUMMARY (See instructions): The proposed work will establish national networking of scientists by providing a new software system (VIVO) and support for scientists using VIVO. Scientists using VIVO will be able to find other scientists and their work. Conversely, scientists using VIVO will be found by other scientists doing similar or complimentary work. VIVO leverages work done over the past five years by Cornell University, supporting researchers and finding of researchers by representing data about them and their activities including publications, awards, presentations and partners. VIVO is fully extensible and based on Sematic Web concepts insuring sound data representation, vastly improved search over existing text based methods and integration of data with other applications. Support for researchers using VIVO will be done by librarians of the research institutions. Librarians provide an existing and fully integrated resource for enabling researchers and the national network. The project will provide six deliverables: 1) A first release of the software to be used at the seven participating institutions focused on insitutitonal resources. This release will be used to help establish internal support for the system and build undersatdning of system value; 2) A second release incorporating all national networking features which will be used by the seven participating institutions to demonstrate the viability and utility of national deployment; 3) A third release incoporporating features requested by the NIH and the project's Executive Advisory Board, fully integrated with the corresponding resource discovery solution, enabling full national networking capability; 4) a community support proceess to insure sustainability; 5) a sustainable, open product development process; and 6) a national, on-going governance process. The national networking of scientists enabled by VIVO will provide a fundamental new capability to improve biomedical research and human health.

RELEVANCE(See instructions): Establishing national networking of scientists will signifcantly improve all of biomedical research in the United States by providing opportunities across all disciplines to identify existing and on-going work, identify potential new collaborations and improve and extend existing collaborations. National networking gives scientists critical new information regarding current scientific activity to improve science, knowledge and human health. PROJECT/PERFORMANCE SITE(S) (if additional space is needed, use Project/Performance Site Format Page)

Project/Performance Site Primary Location

Organizational Name: University of Florida DUNS: 969663814 Street 1: PO Box 115500, 219 Grinter Hall Street 2: City: Gainesville County: Alachua State: FL Province:Country: USA Zip/Postal Code: 32611-5500 Project/Performance Site Congressional Districts: Florida 6th Congressional District

Additional Project/Performance Site Location Organizational Name: Cornell University DUNS: 872612445 Street 1: 201 Olin Library Street 2: City: Ithaca County: Tompkins Province:Country: USA Project/Performance Site Congressional Districts: 22nd District - NY PHS 398 (Rev. 11/07) Page 2

State: NY Zip/Postal Code: 14853-5301

Form Page 2

Program Director/Principal Investigator (Last, First, Middle):

Conlon, Michael

SENIOR/KEY PERSONNEL. See instructions.Use continuation pages as neededto provide the required information in the format shown below. Start with Program Director(s)/Principal Investigator(s). List all other senior/key personnel in alphabetical order, last name first. Name eRA Commons User Name Organization Role on Project Conlon, MichaelMCONLONUFPI Barnes, ChristopherUFDev Lead Borner, KatyKBORNERIUSite Lead Cole, Curtis L.CLCOLEWCMCSite Lead Corson-Rikert, Jonathan W.Cornell IthacaDev Lead Davis, Valrie I.UFSite Team Lead Devare, MedhaCornell IthacaProject Lead Ding, Ying DINGYING IU Ontology Hack, George O.UFEd Tech Team Lead Holmes, Kristi L. WUSTL Outreach Lead Joyce, Gerald F. GJOYCE Scripps Site Lead

OTHER SIGNIFICANT CONTRIBUTORS Name

Organization

Role on Project

Human Embryonic Stem Cells No Yes If the proposed project involves human embryonic stem cells, list below the registration number of the specific cell line(s) from the following list: http://stemcells.nih.gov/research/registry/. Use continuation pages as needed.

If a specific line cannot be referenced at this time, include a statement that one from the Registry will be used.

Cell Line

PHS 398 (Rev. 11/07)

Page 3

Form Page 2-continued Number thefollowingpages consecutively throughout the application. Do not use suffixes such as 4a, 4b.

Program Director/Principal Investigator (Last, First, Middle Michael): Conlon,

SENIOR/KEY PERSONNEL CONTINUED Name eRA Commons Username King, Paula Krafft, Dean B. McDonald, Robert H. McIntosh, Leslie D. Nagarajan, Rakesh RAKESH Noel Jr., Richard J. RJNOELJR Russell Gonzalez, Sara A. Tennant, Michele R. TENNANTM

PHS 398 (Rev. 11/07)

Organization

Scripps Cornell Ithaca IU WUSTL WUSTL Ponce UF UF

Page  4

Role on Project

Dir. Library Site Lead IMP Lead IMP Lead Site Lead Site Lead UF Team Lead UF Team HSC Lead

Form Page 2 - continued

Program Director/Principal Investigator (Last, First, Middle):

Conlon, Michael

Use only if additional space is needed to list additional project/performance sites.

Additional Project/Performance Site Location

Organizational Name: The Trustees of Indiana University DUNS: 60-300-7902 Street 1: IU Digital Library Program Street 2: Wells Library, 1320 E. Tenth Street City: Bloomington County: Monroe State: IN Province:Country: USA Zip/Postal Code: 47405 Project/Performance Site Congressional Districts: IN 009

Additional Project/Performance Site Location Organizational Name: Ponce School of Medicine DUNS: 105742043 Street 1: 395 Industrial Reparada, Zona 2 City: Ponce County: Province:Country: USA Project/Performance Site Congressional Districts: 0-0000

Additional Project/Performance Site Location

Street 2: Ponce

Organizational Name: The Scripps Research Institute DUNS: 7816134920000 Street 1: 10550 North Torrey Pines Road Street 2: City: LaJolla County: LaJolla Province:Country: USA Project/Performance Site Congressional Districts: CA 053

Additional Project/Performance Site Location Organizational Name: Washington University DUNS: 06-855-2207 Street 1: 660 South Euclid Avenue City: St. Louis Province:Country: Project/Performance Site Congressional Districts: 01

County: USA

Street 2: St. Louis

State: PR Zip/Postal Code: 00716-2347

State: CA Zip/Postal Code: 92037

State: MO Zip/Postal Code: 63110

Additional Project/Performance Site Location Organizational Name: Joan & Sanford I. Weill Medical College of Cornell University DUNS: 060217502 Street 1: 1300 York Avenue Street 2: City: New York County: New York State: NY Province:Country: USA Zip/Postal Code: 10065 Project/Performance Site Congressional Districts: 14

PHS 398/2590 (Rev. 11/07)

Page 5

Project/Performance Site Format Page

Program Director/Principal Investigator (Last, First, Middle): Conlon, Michael The name of the program director/principal investigator must be provided at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page.................................................................................................................................................. 1 Description, Project/Performance Sites, Senior/Key Personnel, Other Significant Contributors, and Human Embryonic Stem Cells......................................................................................................... 2 TableofContents..................................................................................................................................... 6 DetailedBudgetforInitialBudgetPeriod.............................................................................................. 7 Budget for Entire Proposed Period of Support ............................................................................................. 11 Budgets Pertaining to Consortium/Contractual Arrangements .......................................................... 15 BiographicalSketch(– Program Director/Principal Investigator Not to exceed four pages each)......... 43 OtherBiographicalSketches (Not to exceed four pages each –See instructions)............................... NA Resources ................................................................................................................................................. 89 Checklist.................................................................................................................................................... 97

Research Plan...........................................................................................................................................

1. 2.

3. 4.

Introduction to Resubmission Application, if applicable(Not to exceed three pages.),or Introduction to Revision Application, if applicable(Not to exceed one page.) .................................................................................................. Specific Aims ..............................................................................................................................................................................

Background and Significance ..................................................................................................................................................... Preliminary Studies/Progress Report (Items 2-5: not to exceed 25 pages).............................

5. Research Design and Methods .................................................................................................................................................. 6. Inclusion Enrollment Report (Renewal or Revision applications only)........................................................................................ 7. Bibliography and References Cited/Progress Report Publication List........................................................................................ 8. Protection of Human Subjects .................................................................................................................................................... 9.InclusionofWomenandMinorities............................................................................................................................................. 10.Targeted/PlannedEnrollmentTable........................................................................................................................................... 11. Inclusion of Children ................................................................................................................................................................... 12. Vertebrate Animals ..................................................................................................................................................................... 13.SelectAgentResearch............................................................................................................................................................... 14. Multiple PD/PI Leadership Plan.................................................................................................................................................. 15. Consortium/Contractual Arrangements ...................................................................................................................................... 16.LettersofSupport(e.g.,Consultants)......................................................................................................................................... 17. Resource Sharing Plan (s)..........................................................................................................................................................

Appendix (Five identical CDs.)

PHS 398 (Rev. 11/07)

Page 6

98

NA

NA 138 NA NA NA NA NA NA NA 142 148 159

Check if Appendix is Included

Form Page 3

Program Director/Principal Investigator (Last, First, Middle):

FROM 9/1/2009

Ferree, Nita

PERSONNEL(Applicant organization only)

SUBTOTALS

64,800

9.6

1.2

2

THROUGH 8/31/2010

DETAILED BUDGET FOR INITIAL BUDGET PERIOD DIRECT COSTS ONLY

SALARY REQUESTED

OTHER EXPENSES(Itemize by category)

SUBTOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD (Item 7a, Face Page)

Page 7

5,358,396 Form Page 4

$

$

4,001,591 1,356,805

FACILITIES AND ADMINISTRATIVE COSTS

PHS 398 (Rev. 11/07)

CONSORTIUM/CONTRACTUAL COSTS

TRAVEL PI=4,800; Governance=19,200; Support=36,000; Developer=4,800 PATIENT CARE COSTS INPATIENT OUTPATIENT ALTERATIONS AND RENOVATIONS(Itemize by category)

TOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD

Months Devoted to Project

6

6,000

6

Buhler, Amy

ROLE ON PROJECT

PD/PI

Bushousen, Ellie

Conlon, Michael

Barnes, Christopher

CONSORTIUM/CONTRACTUAL COSTS

Dev Lead

Site Team Lead

3

Cal. Mnths

UF Team HSC

Site Support Librarian

UF Team HSC

SUPPLIES(Itemize by category) Small items

CONSULTANT COSTS EQUIPMENT(Itemize) 8 servers @ 6,200/each=49,600; 10 workstations @2,000/each=20,000; 6 storage @ 3,000/each=18,000

Botero, Cecilia

MeSH Expert

NAME

1.2

Davis, Valrie

DIRECT COSTS

87,600

983,126

330,268

1,313,394

2,529,798

DOLLAR AMOUNT REQUESTED(omit cents)

INST.BASE SALARY

FRINGE BENEFITS

TOTAL

Conlon, Michael

Summer Mnths

Acad. Mnths

THROUGH 08/31/2010

Jesano, Rae

ROLE ON PROJECT

PD/PI

TOTAL

FRINGE BENEFITS

6

Russell, Sara G.

UF Team Librarian

UF Team HSC

UF Team Lead

UF Team HSC

1.2

1.2

1.2

2.4

INST.BASE SALARY

SALARY REQUESTED

1,313,394

Acad. Mnths

Summer Mnths

Cal. Mnths

UF Team HSC Lead

SUBTOTALS

3

DIRECT COSTS

CONSORTIUM/CONTRACTUAL COSTS

PHS 398 (Rev. 11/07)

CONSORTIUM/CONTRACTUAL COSTS

983,126

OTHER EXPENSES(Itemize by category)

330,268

Page 8

SUBTOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD (Item 7a, Face Page)

4,001,591 1,356,805

FACILITIES AND ADMINISTRATIVE COSTS

Johnson, Margeaux

Ed Tech Team Lead

Hack, George

DOLLAR AMOUNT REQUESTED(omit cents)

NAME

Program Director/Principal Investigator (Last, First, Middle):

Schaefer, Nancy

PERSONNEL(Applicant organization only)

Tennant, Michele

SUPPLIES(Itemize by category)

TRAVEL PATIENT CARE COSTS INPATIENT OUTPATIENT ALTERATIONS AND RENOVATIONS(Itemize by category)

TOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD

FROM 09/1/2009

Months Devoted to Project

DETAILED BUDGET FOR INITIAL BUDGET PERIOD DIRECT COSTS ONLY

Conlon, Michael

$

5,358,396 Form Page 4

$

CONSULTANT COSTS EQUIPMENT(Itemize)

2,529,798

Turner, Alicia

TOTAL

FRINGE BENEFITS

THROUGH 08/31/2010

112,430

Conlon, Michael

59,187

CONSORTIUM/CONTRACTUAL COSTS

SUBTOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD (Item 7a, Face Page)

TOTAL DIRECT COSTS FOR INITIAL BUDGET PERIOD

85,000

TBA

TBA

FROM 09/1/2009

2,529,798

5,358,396 Form Page 4

$

4,001,591 1,356,805

$

FACILITIES AND ADMINISTRATIVE COSTS

330,268

Page 9

TBA

CONSULTANT COSTS EQUIPMENT(Itemize)

Site Support Tech

12

Team Lead

6

Developer

PD/PI

ROLE ON PROJECT

Program Director/Principal Investigator (Last, First, Middle):

Cal. Mnths

Months Devoted to Project

OTHER EXPENSES(Itemize by category)

PHS 398 (Rev. 11/07)

CONSORTIUM/CONTRACTUAL COSTS

Team Lead

12

6

6

DETAILED BUDGET FOR INITIAL BUDGET PERIOD DIRECT COSTS ONLY

90,000

Williams, Stephen V.

Research Asst

NAME

PERSONNEL(Applicant organization only)

SUPPLIES(Itemize by category)

TBA

TRAVEL PATIENT CARE COSTS INPATIENT OUTPATIENT ALTERATIONS AND RENOVATIONS(Itemize by category)

85,000

SUBTOTALS

Developer

12

45,000

14,187

85,000

59,187

27,430

45,000

INST.BASE SALARY

SALARY REQUESTED

Acad. Mnths

Summer Mnths

90,000

14,187

DOLLAR AMOUNT REQUESTED(omit cents)

983,126

85,000

DIRECT COSTS

27,430

112,430

1,313,394