Antimicrobial and antioxidant activities of Cortex Magnoliae Officinalisand some other medicinal plants commonly used in South-East Asia

Chan Lai, Cheah, Saw, Weng Wanyu, Heng

Description

Eight medicinal plants were tested for their antimicrobial and antioxidant activities. Different extraction methods were also tested for their effects on the bioactivities of the medicinal plants. Methods Eight plants, namely Herba Polygonis Hydropiperis ( Laliaocao ), Folium Murraya Koenigii ( Jialiye ), Rhizoma Arachis Hypogea ( Huashenggen ), Herba Houttuyniae ( Yuxingcao ), Epipremnum pinnatum ( Pashulong ), Rhizoma Typhonium Flagelliforme ( Laoshuyu ), Cortex Magnoliae Officinalis ( Houpo ) and Rhizoma Imperatae ( Baimaogen ) were investigated for their potential antimicrobial and antioxidant properties. Results Extracts of Cortex Magnoliae Officinalis had the strongest activities against M. Smegmatis , C. albicans , B. subtilis and S. aureus . Boiled extracts of Cortex Magnoliae Officinalis , Folium Murraya Koenigii, Herba Polygonis Hydropiperis and Herba Houttuyniae demonstrated greater antioxidant activities than other tested medicinal plants. Conclusion Among the eight tested medicinal plants, Cortex Magnoliae Officinalis showed the highest antimicrobial and antioxidant activities. Different methods of extraction yield different spectra of bioactivities.

Informations

• Publié par: biomed
• Publié le: 01 janvier 2008
• Nombre de lectures: 12
• Langue: English

Extrait

Chinese Medicine

BioMedCentral

Open Access Research Antimicrobial and antioxidant activities ofCortex Magnoliae Officinalisand some other medicinal plants commonly used in South-East Asia 1 12 1 Lai Wah Chan, Emily LC Cheah, Constance LL Saw, Wanyu Wengand 1 Paul WS Heng*

1 2 Address: Departmentof Pharmacy, Faculty of Science, National University of Singapore, 18 Science Drive 4, Singapore 117543 andCenter for Cancer Prevention Research, Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, State University of New Jersey, 160 Frelinghuysen Road, Piscataway, New Jersey 08854, USA Email: Lai Wah Chan  [e-mail]; Emily LC Cheah  [e-mail]; Constance LL Saw  [e-mail]; Wanyu Weng  [e-mail]; Paul WS Heng*  [e-mail] * Corresponding author

Published: 28 November 2008Received: 4 February 2008 Accepted: 28 November 2008 Chinese Medicine2008,3:15 doi:10.1186/1749-8546-3-15 This article is available from: http://www.cmjournal.org/content/3/1/15 © 2008 Chan et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract Background:Eight medicinal plants were tested for their antimicrobial and antioxidant activities. Different extraction methods were also tested for their effects on the bioactivities of the medicinal plants.

Methods:Eight plants, namelyHerba Polygonis Hydropiperis(Laliaocao),Folium Murraya Koenigii (Jialiye),Rhizoma Arachis Hypogea(Huashenggen),Herba Houttuyniae(Yuxingcao),Epipremnum pinnatum(Pashulong),Rhizoma Typhonium Flagelliforme(Laoshuyu),Cortex Magnoliae Officinalis (Houpo) andRhizoma Imperatae(Baimaogen) were investigated for their potential antimicrobial and antioxidant properties.

Results:Extracts ofCortex Magnoliae Officinalishad the strongest activities againstM. Smegmatis, C. albicans,B. subtilisandS. aureus. Boiled extracts ofCortex Magnoliae Officinalis,Folium Murraya Koenigii, Herba Polygonis HydropiperisandHerba Houttuyniaedemonstrated greater antioxidant activities than other tested medicinal plants.

Conclusion:Among the eight tested medicinal plants,Cortex Magnoliae Officinalisshowed the highest antimicrobial and antioxidant activities. Different methods of extraction yield different spectra of bioactivities.

Background Some medicinal plants used in traditional Chinese medi cine are effective in treating various ailments caused by bacterial and oxidative stress. As new drugresistant bacte ria strains emerge, especially methicillinresistantStaphy lococcus aureusand vancomycinresistant enterococci, new drugs or adjuvants have been actively searched in medici

nal plants [13]. New antioxidants such as plant phenolics [47] are sought for general health maintenance, anti aging and chemoprevention.

Eight medicinal plants, namelyHerba Polygonis Hydropi peris(Laliaocao),Folium Murraya Koenigii(Jialiye),Rhizoma Arachis Hypogea(Huashenggen),Herba Houttuyniae(Yux

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