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Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma [Elektronische Ressource] / presented by Hui Wu

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DISSERTATION submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma presented by Hui Wu born in Fu‘an, P. R. China Heidelberg 2010 Accepted by the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany: September 14th, 2010 Referees: Priv.-Doz. Dr. Karsten Rippe Prof. Dr. Peter Lichter Day of the oral examination: October 26th, 2010 The investigations of this dissertation were performed from April 2006 to August 2010 under the supervision of Prof. Dr. Peter Lichter, Prof. Dr. Stefan Joos, Dr. Armin Pscherer and PD. Dr. Michael A. Rogers in the Division of Molecular Genetics at the German Cancer Research Center (DKFZ), Heidelberg, Germany. Publication Wu H, Haag D, Muley T, Warth A, Zapatka M, Toedt G, Roger MA, Pscherer A, Joos S, Müller-Decker K, Hahn M, Rieke RJ, Miester M, Schnabel P, Hoffmann H, Lichter P.
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DISSERTATION
submitted to the
Combined Faculties for the Natural Sciences and for Mathematics
of the Ruperto-Carola University of Heidelberg, Germany
for the degree of
Doctor of Natural Sciences




Tumor-microenvironment interactions studied by zonal
transcriptional profiling of squamous cell lung carcinoma






presented by
Hui Wu
born in Fu‘an, P. R. China
Heidelberg 2010
































Accepted by the Combined Faculties for the Natural Sciences and for Mathematics of the
Ruperto-Carola University of Heidelberg, Germany: September 14th, 2010
Referees:
Priv.-Doz. Dr. Karsten Rippe
Prof. Dr. Peter Lichter
Day of the oral examination: October 26th, 2010






















































The investigations of this dissertation were performed from April 2006 to August 2010
under the supervision of Prof. Dr. Peter Lichter, Prof. Dr. Stefan Joos, Dr. Armin Pscherer
and PD. Dr. Michael A. Rogers in the Division of Molecular Genetics at the German Cancer
Research Center (DKFZ), Heidelberg, Germany.

































Publication
Wu H, Haag D, Muley T, Warth A, Zapatka M, Toedt G, Roger MA, Pscherer A, Joos S,
Müller-Decker K, Hahn M, Rieke RJ, Miester M, Schnabel P, Hoffmann H, Lichter P.
Tumor-microenvironment interactions studied by zonal transcriptional profiling of
squamous cell lung carcinoma
In preparation...






















































Declarations
I hereby declare that I have written the submitted dissertation ‗Tumor-microenvironment
interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma‘
myself and in this process have used no other sources or materials than those expressly
indicated. I hereby declare that I have not applied to be examined at any other institution,
nor have I used the dissertation in this or any other form at any other institution as an
examination paper, nor submitted it to any other faculty as a dissertation.

_____________________________ _____________________________
(Place, Date) Hui Wu









































































































To A.W.
& my family




















































































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