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Acute Coronary Syndromes

320 pages
The management of non-ST segment elevation acute coronary syndromes (NSTE-ACS) has rapidly evolved over the last few years and many guidelines have been provided and already updated. This book is based on the latest ESC Guidelines and reports the current knowledge in NSTE-ACS, together with the most recent therapeutic options and the different strategies that can be applied according to the clinical status of patients.

International experts address the different aspects of NSTE-ACS and bring useful information to clinicians, interventionalists and surgeons involved in the difficult management of these patients.

The ESC Education Series
This book is part of the ESC Education Series. The series is designed to provide medical professionals with the latest information about the understanding, diagnosis and management of cardiovascular diseases. Where available, management recommendations are based on the established European Guidelines, which encompass the best techniques to use with each cardiac disease. Throughout the series, the leading international opinion leaders have been chosen to edit and contribute to the books. The information is presented in a succinct and accessible format with a clinical focus.

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List of contributors, viii
Preface, x
Section one: Epidemiology
Chapter 1Epidemiology of non-ST-segment elevation acute coronary syndromes, 3 David Hasdai and Alexander Battler
Section two: Pathophysiology
Chapter 2 Erling Falk
Pathologic findings in acute coronary syndromes, 11
Chapter 3Vascular biology of acute coronary syndromes, 24 Lina Badimon
Section three: Clinical aspects of ACS
Chapter 4Clinical aspects of acute coronary syndromes, 43 Eugene McFadden
Chapter 5Circulating biomarkers for risk stratification, 52 Christopher Heeschen
Section four: Investigation in ACS
Chapter 6Coronary angiography, angioscopy, and intravascular ultrasound in non-ST-segment elevation acute coronary syndromes, 65 Eric Van Belle, Christophe Bauters, François Schiele, and Michel E. Bertrand
Chapter 7New coronary imaging in acute coronary syndrome, 78 Pim J. de Feyter, Evelyne Regar, and Nico R.A. Mollet
Section five: Special groups of patients
Chapter 8Acute coronary syndromes in specialgroups of patients, 97 Piero O. Bonetti, Michael J. Zellweger, Christoph Kaiser, and Matthias E. Pfisterer
Section six: Pharmacological treatment
Chapter 9Antiischemic treatment (nitrates,β-blockers, calcium antagonists), 109 David McCarty, Colum G. Owens, and A.A. Jennifer Adgey
Chapter 10Antiplatelet therapies: aspirin, thienopyridines, and glycoprotein IIb/IIIa receptor inhibitors, 116 Jaydeep Sarma and Keith A.A. Fox
Chapter 11Antithrombin drugs: LMWH, unfractionated heparin, direct thrombin inhibitors, 139 Raphaelle Dumaine and Gilles Montalescot
Chapter 12Statin therapy in ACS, 152 François Schiele
Section seven: Myocardial revascularization
Chapter 13Percutaneous coronary interventions and stenting/CABG in non-ST-segment elevation acute coronary syndromes, 165 Nicolas Meneveau and Jean-Pierre Bassand
Section eight: Therapeutic strategy
Chapter 14Risk stratification and therapeutic strategy, 187 Christian W. Hamm
Chapter 15Indication for revascularization in non-ST-elevation acute coronary syndrome, 199 Lars Wallentin
Chapter 16Management of patients with nonamenable lesions for myocardialrevascularization,211 Victor Legrand
Chapter 17Non-ST-segment elevation coronary syndromes: European Society of Cardiology guidelines, 225 Michel E. Bertrand
Chapter 18Non-ST-segment elevation acute coronary syndromes: ACC/AHA guidelines, 236 Pierre Théroux
Chapter 19From guidelines to registries, 248 Luigi Tavazzi
Section nine: Secondary prevention Chapter 20Secondary prevention after acute episode of patients presenting with nonpersistent ST-segment elevation, 261 Michel E. Bertrand
Chapter 21How to detect vulnerable plaque, 270 Dirk Boese and Raimund Erbel
Chapter 22Localversus systemic prevention treatment, 281 Mario Togni and Bernhard Meier
Conclusions, 294
Index, 295