Generation of genetically modified mice with conditional alleles of Dyrk1a [Elektronische Ressource] : a minimal animal model of Down syndrome / presented by Claus Beck

Claus.Beck

Description

Dissertation submitted to the Combined Faculties for the Natural Sciences and for Mathematics of the Ruperto-Carola University of Heidelberg, Germany for the degree of Doctor of Natural Sciences Presented by Diplom-Biologe Claus Beck born in: Mannheim, Germany Oral-examination: _________ Title Generation of genetically modified mice with conditional alleles of Dyrk1a A minimal animal model of Down syndrome Referees: Prof. Dr. Peter H. Seeburg Prof. Dr. Dusan Bartsch 2 Meinem Vater und meiner Familie 3The following work was performed at the Central Institute for Mental Health Mann-heim (ZI), from May 2002 to July 2006, in thea tloabryo rand under supervision of Prof. Dr. Dusan Bartsch. I would like to thank Prof. Dr. Dusan Bartsch ifvoirn gg me the opportunity to work for my Ph.D. thesis in the Department of MoleculaBri ology. I deeply appreciate his excellent supervision, constant encouragement and uspport throughout my work. Furthermore I am very grateful to Prof. Dr. Pete.r HSeeburg for being my other supervisor. I am deeply thankful to my colleagues Brigitte Peslod, Uwe Leimer and Tillmann Weber for their support, beneficial discussions, gsgeustions and motivation espe-cially in the beginning of my work and during theu ibldup of the laboratory.

Sujets

• Gesundheit

Informations

• Publié par: ruprecht-karls-universitat_heidelberg
• Publié le: 01 janvier 2006
• Nombre de lectures: 46
• Langue: English
• Poids de l'ouvrage: 4 Mo

Extrait