Identification of growth suppressive genes as cyclin A1 targets in acute myeloid leukemia by microarray analysis [Elektronische Ressource] / by Amber Yasmeen
University of Münster Department of Medicine Hematology and Oncology - Director: Univ.-Prof. Dr. W. E. Berdel - Identification of Growth Suppressive Genes as Cyclin A1 Targets in Acute Myeloid Leukemia by Microarray Analysis A dissertation submitted to the Department of Medicine University of Münster (WWU) for the degree of doctor rerum medicinalium (Dr. rer. medic) by Amber Yasmeen 2004 Printed with permission from the Department of Medicine, University of Münster (WWU) Dean: Univ.-Prof. Dr. Heribert Jürgens 1. Examiner: Univ.-Prof. Dr. Hubert Serve 2. Examiner: Prof. Dr. O. M. Koch Day of Oral Examination: 23-01-2004 University Hospital Münster Clinic and Polyclinic for Inner Medicine A -Director: Univ. Prof. Dr. W. E. Berdel- 1. Examiner: Univ. Prof. Dr. Hubert Serve 2. Examiner: Prof. Dr. O. M. Koch Summary Identification of growth suppressive genes as cyclin A1 targets in acute myeloid leukemia by microarray analysis Amber Yasmeen Cyclin A1 is a tissue specific A-type cyclin, which is essential for spermatogenesis. Cyclin A1 is also highly expressed in blasts of acute myeloid leukemia.