Nuclear Cardiology and Multimodal Cardiovascular Imaging

Marcelo Fernando Di Carli

Description

Recent years have seen numerous advances in cardiovascular nuclear medicine technology, leading to more precise diagnoses and treatment and an expanded understanding of the molecular basis for cardiac disease. Nuclear Cardiology and Multimodal Cardiovascular Imaging is a one-stop, comprehensive guide to the diagnostic and clinical implications of this complex and increasingly important technology. Part of the Braunwald family of renowned cardiology references, it provides cutting-edge coverage of multimodal cardiac imaging along with case vignettes and integrated teaching content—ideal for cardiologists, cardiology fellows, radiologists, and nuclear medicine physicians.

• Features all the latest cardiovascular nuclear medicine studies with practical, evidence-based implications for personalized patient evaluation and treatment.

• Presents a consistent, patient-centered approach using integrated case vignettes correlated with specific nuclear medicine imaging findings. Discusses patient assessment criteria, risk factor criteria, pathology, evaluation criteria, outcomes, and other clinical implications.

• Covers a full range of imaging technologies, including SPECT/CT, PET/CT, and CT/MR hybrid radionuclide cardiovascular imaging studies.

• Addresses emerging clinical applications of nuclear imaging techniques for precision-based medicine, including targeted molecular imaging and cell therapies.

• Includes sections on instrumentation/principles of imaging; protocols and interpretation; applications in coronary artery disease, special populations, and heart failure; artificial intelligence, and more.

• Contains guidelines and appropriate use documents to provide appropriate context for clinicians.

• Features hundreds of high-quality figures including multimodal cardiac imaging studies, anatomic illustrations, and graphs.

• Provides Key Point summaries, 50 procedural videos, and 100 multiple-choice questions and answers to reinforce understanding and facilitate review.

Sujets

• Médecine
• Spécialités médicales
• Medical
• Cardiology

Informations

• Publié par: Elsevier
• Date de parution: 17 novembre 2021
• Nombre de lectures: 0
• EAN13: 9780323763042
• Langue: English
• Poids de l'ouvrage: 5 Mo

Extrait

Nuclear Cardiology and Multimodal Cardiovascular Imaging
A Companion to Braunwald’s Heart Disease
Marcelo Fernando Di Carli, MD
Executive Director, Cardiovascular Imaging, Departments of Medicine and Radiology, Chief, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women’s Hospital, Seltzer Family Professor of Radiology and Medicine, Harvard Medical School, Boston, Massachusetts
Table of Contents
Cover image
Title page
Copyright
Dedication
Contributors
Preface
Video contents
Braunwald’s heart disease family of books
Section I. Instrumentation and Principles of Imaging
1.  Single photon emission computed tomography
Introduction
Detectors
Collimators
System designs for cardiac SPECT imaging
Factors affecting image quality
Reconstruction
Cardiac gating
Future developments
Questions
References
2.  Positron emission tomography
Introduction
PET physics fundamentals
PET imaging technology
PET data acquisition
PET image reconstruction
PET image quality
Emerging technologies
Questions
References
3.  Principles of myocardial blood flow quantification with SPECT and PET imaging
Introduction
Myocardial blood flow measurements with PET and SPECT
Myocardial blood flow assessment with SPECT
Questions
References
Section II. Imaging Protocols and Interpretation
4.  Radiopharmaceuticals for clinical SPECT and PET and imaging protocols
Introduction
Current radiotracers for cardiac imaging
Imaging protocols for cardiac SPECT and PET
Radiation exposure
Guidelines
Questions
References
5.  Recognizing and preventing artifacts with SPECT and PET imaging
Introduction
SPECT imaging
PET imaging
Conclusion
Questions
References
6.  Approaches to minimize patient dose in nuclear cardiology
Introduction
New technology to limit patient dose
Best practices to limit patient dose
Conclusions
Questions
References
Section III. Applications of Nuclear Cardiology in Coronary Artery Disease
7.  Patients with new-onset stable chest pain syndromes
Introduction
Initial assessment of patients with new-onset chest pain
Incremental value of imaging tests
Diagnostic value of radionuclide imaging
Added value of coronary artery calcium score
Applications of radionuclide imaging in patients with new-onset stable chest pain syndrome
Questions
References
8.  Applications of nuclear cardiology in known stable coronary artery disease
Introduction
Role of non-invasive imaging in patients with stable coronary artery disease
Patient-centered applications of radionuclide MPI in patients with known coronary artery disease: Case-based discussion
New developments for radionuclide myocardial perfusion imaging
Questions
References
9.  Patient with prior revascularization
Introduction
Approach to patient evaluation and test selection
Patient-centered clinical applications
Future directions and emerging applications
Questions
References
10.  Preoperative risk evaluation: When and how?
Introduction
Risk assessment
Noninvasive testing for preoperative risk assessment
Patient-centered approach to preoperative risk assessment
Questions
References
11.  Imaging in patients with acute chest pain in the emergency department
Scope of the problem
Evaluation of patients with chest pain in the emergency department
The ischemic cascade and the rationale for use of noninvasive imaging
Patient-centered applications of noninvasive imaging in patients with suspected acute cardiac ischemia
Conclusion
Questions
References
12.  Assessing the biology of high-risk plaque features with molecular imaging
Introduction
Rationale for high-risk plaque imaging
18 F-FDG PET imaging of vascular inflammation
18 F-NaF imaging of active calcification
Other radionuclide probes for plaque imaging
Imaging plaque biology and composition using pet/mri
Summary
Questions
References
Section IV. Applications of Nuclear Cardiology in Select Populations
13.  Patients with suspected coronary microvascular dysfunction
Introduction
Evaluation of suspected coronary microvascular dysfunction
Patient-centered clinical applications
Emerging applications
Questions
References
14.  Patient with cardiometabolic disease
Introduction
Technical considerations
Patient-centered clinical applications
Questions
References
15.  Patient with chronic kidney disease
Introduction
Patient-centered clinical applications of radionuclide and multimodality imaging in patients with CKD
Questions
References
16.  Women with suspected ischemic heart disease
Introduction
Sex differences in ischemic heart disease
Moving beyond obstructive coronary artery disease
Patient-centered clinical applications of imaging in women
Patient selection for testing
Extended algorithm of diagnostic testing strategies
Questions
References
17.  Key concepts in risk stratification and cost-effectiveness using nuclear scintigraphy in stable coronary artery disease
Introduction
Risk stratification and incremental prognostic value
Principles of prognostication and risk stratification
Post-MPI resource utilization and implications for risk assessment
Radionuclide MPI and patient management
Cost effectiveness of radionuclide MPI and its relationship to alternative strategies and modalities
Questions
References
Section V. Applications of Nuclear Cardiology in Heart Failure
18.  The patient with new-onset heart failure
Introduction
Patient-centered applications of multimodality imaging in patients with new-onset heart failure
Questions
References
19.  Metabolic remodeling in heart failure
Introduction
Basic concepts on myocardial metabolism
Methods for measuring substrate metabolism in the human heart
Assessing key myocardial metabolic pathways
Risk factors for heart failure
Myocardial metabolic phenotypes in cardiomyopathy and heart failure
Myocardial metabolic effects of standard heart failure therapies
Myocardial metabolic modulation in heart failure
Future directions
Questions
References
20.  Patient with ischemic heart failure: Ischemia and viability assessment and management
Introduction
Ischemic heart failure
Imaging techniques for the evaluation of ischemia and viability
Patient-centered imaging applications in ischemic heart failure
Critical appraisal of the evidence regarding the use of myocardial ischemia and viability testing to guide patient management
Questions
References
21.  Novel approaches for the evaluation of arrhythmic risk
Introduction
Risk stratification of arrhythmic risk
Patient-centered applications of radionuclide and multimodality imaging for the evaluation of arrhythmic risk
Potential role for radionuclide imaging to guide arrhythmia ablation
Questions
References
22.  Screening for transplant vasculopathy
Introduction
Clinical aspects of cardiac allograft vasculopathy
Noninvasive imaging approaches for screening of cardiac allograft vasculopathy
Patient-centered applications of radionuclide imaging and multimodality imaging in patients after heart transplantation
Questions
References
23.  Patient with known or suspected cardiac sarcoidosis
Introduction
Diagnosis of cardiac sarcoidosis
Role of imaging in cardiac sarcoidodis
Patient-centered evaluation of suspected or known cardiac sarcoidosis
Questions
References
24.  Patients with known or suspected amyloidosis
Introduction
Epidemiology
Clinical presentation
Radionuclide imaging
99m Technetium imaging protocols
Patient-centered applications of imaging in cardiac amyloidosis
Future directions
Questions
References
25.  Patients undergoing cancer treatment
Introduction
Patient-centered applications of multimodality imaging in cardio-oncology
Questions
References
26.  Molecular imaging of myocardial infarction and remodeling
Introduction
Molecular repair mechanisms after acute myocardial infarction: Inflammation, fibrosis, and angiogenesis
Multimodality imaging after acute myocardial infarction
Future challenges
Questions
References
27.  Patient with mechanical dyssynchrony
Introduction
Imaging methods to assess mechanical dyssynchrony
Clinical applications
Questions
References
Section VI. Emerging Clinical Applications
28.  Aortic stenosis and bioprosthetic valve degeneration
Introduction
Computed tomography
Positron emission tomography
Left ventricular remodeling and the role of positron emission tomography imaging
Image optimization and current state of the art
Applications of 18 F-Fluoride positron emission tomography
End point in clinical trials
Patient management
Bioprosthetic valve degeneration
Patient-centered clinical applications
Acknowledgments
Questions
References
29.  Infective endocarditis
Introduction
Technical considerations
Image interpretation
Clinical applications of 18 F-FDG-PET/CCTA
Additional benefits of whole-body positron emission tomography/computed tomography
Diagnostic challenges
Other nuclear imaging techniques
Role of nuclear imaging in the multimodality evaluation of infective endocarditis
Future directions
Summary
Questions
References
30.  Large-vessel vasculitis
Introduction
Classification and diagnosis of large-vessel vasculitides
Multimodality imaging of large-vessel vasculitides
Patient-centered clinical applications
Emerging applications of large-vessel vasculitis imaging
Questions
References
31.  Peripheral arterial disease
Epidemiology and the natural history of peripheral arterial disease
Compartments of peripheral arterial disease: Macrovasculature, microvasculature, angiosomes, and collateral vessels
Standard noninvasive evaluation of peripheral arterial disease
Questions
References
Section VII. Artific