M1 Nanosciences

Guy Royal

Description

Niveau: Supérieur, Master, Bac+4
104/03/2008 M1-Nanosciences Supramolecular Chemistry for Nanosciences Guy Royal & L. P. Lévy

• ion-dipole


• stacking interactions ?


• equilibrium can


• nobel prize


• der walls


• bonding ? pi?pi


• host-guest complex


• coordination bonds

Sujets

• Nobel Prize
• Host-guest chemistry

Informations

• Publié par: larec
• Publié le: 01 mars 2008
• Nombre de lectures: 7
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Supramolecular C hemi s try for Nanosci e nces

04/03/2008

Guy Royal & L. P. Lévy

M 1 -Nanos ci en c e s

1

           

Jean-Marie Lehn

04/03/2008

1987 Nobel prize to:

Donald J. Cram Jean-Marie Lehn Charles J. Pedersen

For their development of the field of supramolecular chemistry

M 1 -Nanos ci en c e s

2

                    

 H o st-Guest c h e m i stry

+

Selective

Host-Guest complex (Supramolecule)

molecular recognition

Non-Covalent interactions are involved

Host molecule (Receptor) Guest molecules (Substrate)  Hydrogen bonding  ϑ%ϑ Stacking interactions  Electrostactic interactions (ion-ion, ion-dipole, dipole-dipole)  Van der Walls forces  Hydrophobic/solvatophobic interactions  Coordination bonds (Metal-donor bonds) M 1 -Nanos ci en c e s

04/03/2008

3

                 

 H o st-Guest c h e m i stry

+

Host molecule (Receptor) Guest molecules (Substrate)

04/03/2008

O O O O O O [18]Crown-6

K +

Selective

M 1 -Nanos ci en c e s

Host-Guest complex (Supramolecule) molecular recognition

O O O K + O O O

4

                 

 H o st-Guest c h e m i stry

+

Host molecule (Receptor) Guest molecules (Substrate)

Selective

Reversibility

Host-Guest complex (Supramolecule)

molecular recognition

 Reversibility:  - The thermodynamic equilibrium can be reached - Dynamic architectures - Change in constitution, shape, properties… - Capacity of error correction (not available for fully covalent systems)

04/03/2008

M 1 -Nanos ci en c e s

5

    

               

Shape, size, proper ti e s (chemical, photochemical, redox, …)

04/03/2008

 

M 1 -Nanos ci en c e s



 

       



6

  

 

Fe

04/03/

O O O O O O N N

    



"Building blocks": -Complexing molecules -Redox units -Photosensitive molecules -Conjugated or saturated molecules -Carbon nanotubes, fullerenes… R -Molecules that can be attached onto a surface -…

From very simple to very complex… Only limited by imagination and… organic synthesis !!

M 1 -Nanos ci en c e s

7

    

Fe

04/03/

O O O O O O

    

N N 

Light absorbed O O O N O O

No Light emitted

Self R assembly  

O Light absorbed O   O O

Light emitted M 1 -Nanos ci en c e s

P h o t o ch emi ca l sensing a nd   dete c t i on

A. P. De Silva, S. A. De Silva, J. Chem. Soc, Chem. Commun ., 1986 , 1709

8

N N Zn N N

               

R

  

R

N N Zn F N N e G R'NH R HNR' R Gues ecies N N e (neutral ts m p olecule) R F R Zn N N

N N Zn N N

Fe

NH

G R N N Zn N N

self-assembly

Fe

N H

R Dynamic system R Supramolecular structure Application: electrochemical detection of guest molecules 04/03/2008 (dimer) C. Buche M r 1 , - C N . a   n H o . s c D i e n v c il e l s ers, J.-C. Moutet, G. Royal, E. Saint-Aman. 9 Chem. Commun., 2003 , 888-889.

       

Cyclodextrins HO O O OH  O HO  OH  O  HO HO HO O O HO Lipophilic O O H HO cavity OH O OH OH OH O  HO  OH  O  HO  O O OH  Hydrophilic periphery

=

H 3 C O S O N H N OOH

NH O O NH 2 N N H 2 N N  N O O H N N HN N O O H 2 N

Solubilization of R. Breslow, Acc. Chem. Res. 1995 , 28 , 146 organic compounds Y. Fukazawa et al ., Tetrahedron. Lett., 2001 , 42 , 3203 (drugs…) in w M a 1 t - e N r anos ci e J n . c T e . s Rademacher, C. Czarnick, JACS , 1993 , 3 1 0 0 18

04/03/2008

   

 



R

Ordered Self-Assembled Monolayer (SAM)

Modification of surfaces

New materials

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