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Publié par | technische_universitat_berlin |
Publié le | 01 janvier 2011 |
Nombre de lectures | 38 |
Langue | English |
Poids de l'ouvrage | 3 Mo |
Extrait
Comparing the costeffectiveness of a new hospitalbased
health technology in a lowmiddleincome country
(Vietnam) with a highincome country (Germany)
Vorgelegt von
MD. MBA
Duong Anh Vuong
aus Phutho
Von der Fakultät VII - Wirtschaft und Management
der Technischen Universität Berlin
zur Erlangung des akademischen Grades
Doktor der Gesundheitswissenschaften / Public Health
Dr. P.H.
Genehmigte Dissertation
Promotionsausschuss:ionsauschuss:ProVorsitzender:
Vorsitzender: Prof. Dr. Jacqueline Müller-Nordhorn
Gutachter: Prof. Dr. Reinhard Busse
Gutachter: Prof. Dr. Jonas Schreyögg
Gutachter: Prof. Dr. Dirk Rades
Tag der wissenschaftlichen Aussprache: 28.06.2011
Berlin 2011
D83
i
TABLE OF CONTENT
List of figures .............................................................................................................................. v
List of tables ...................................................................................................... vi
Acknowledgement .................................................................................................................. viii
Summary ............................................................................................................. x
Zusammenfassung .................................................................................................................. xiii
Abbreviation ......................................................................... xvii
Part I. Introduction ................ ......................... ........................ ........................ ....................... ... 1
Explosion of new health technology ................................................................... 1
Health technology assessment ........................................................................... 3
Diffusion of new health technology in high- and low-middle-income countries ....................... 6
Aims of this thesis ....................................................................................................................... 8
Outline of this thesis ............................................................................ 9
Part II. Epidemiology and therapeutic management of brain metastasis .......... 10
Chapter 1. Temporal trends of cancer incidence in Vietnam, 1993-2007 ..................... 10
Abstract ..................................................................................................................................... 11
Introduction .............................................................................. 12
Methods ............................................................................................................ 13
Results ............................................................... 14
Discussion ......................................................................................................... 18
Conclusion ................................................................................................................................ 21
Chapter 2. Brain Metastases: Epidemiology and therapeutic management ................ . 22
Epidemiology ............................................................................................................................ 22
Signs and symptoms ......................................................................................... 23
Prognostic factors ..................................................................................................................... 25
Diagnosis and treatment .................................................................................... 33
Appendix: Primary brain tumors .............................................................................................. 49
Chapter 3. Extracranial metastatic patterns at the occurrence of brain metastases ... 53
Introduction ............................................................................................................................... 55
Material and methods ......................................................................................... 55
Results .............................................................................................................. 57
Discussion .......................................................... 61
ii
Conclusion ................................................................................................................................ 63
Part III. Health care services and Hospital finance ...................................... 65
Chapter 4. Mental health in Vietnam: Burden of disease and availability of services 65
Abstract ..................................................................................................................................... 66
Introduction .............................................................................. 67
Methods ............................................................................................................ 67
Results ............................................................... 68
Discussion ......................................................................................................... 74
Conclusion ................................................................................................................................ 76
Chapter 5. Determining the impacts of hospital cost-sharing on the uninsured in
Vietnam ........................................................................................................................... 77
Abstract ............................................................................................................. 78
Introduction .............................................................................. 79
Background ................................................................................ 79
Methods .................................................................................................................................... 82
Results ....................................... 86
Discussion ................................................................................................................................. 89
Conclusion ........................................................................................................ 91
Chapter 6. Health care system in Germany ..................................................................... 92
Introduction ....................................................................................................... 92
Demography and health status ......................................................................... 93
Organizational structure and personnel resources .................................................................... 94
Health care personnel resources ....................................................................... 98
Patient empowerment ............................................................................................................. 101
Health care financing ...................................................................................... 102
Health care service provision ......................................................................... 112
Quality management ............................................................................................................... 121
Conclusion ............................................................................. 124
Part IV. Cost-effectiveness of a new hospital-based health technology in a low-middle-
income country and a high-income country ....................................................................... 126
Chapter 7. The cost-effectiveness of stereotactic radiosurgery versus surgical
resection in the treatment of brain metastasis in Vietnam from the perspective of
patients and families ............................................................................................................. 126
iii
Abstract ................................................................................................................................... 127
Introduction ............................................................................ 128
Material and methods ....................................................................................... 128
Results ............................................................................................................ 133
Discussion ........................................................ 137
Conclusion .............................................................................................................................. 140
Appendix: Cost-effectiveness of SRS versus SR in the treatment of brain metastasis in
Vietnam adjusted to the Health Insurance perspective ........................................................... 141
Chapter 8. Cost-effectiveness of stereotactic radiosurgery versus surgical resection
in the treatment of brain metastasis with German statutory health insurance
perspective .............................................................................................................