Investigation of novel process analytical technology (PAT) tools for use in freeze-drying processes [Elektronische Ressource] / vorgelegt von Stefan Christian Schneid
Investigation of Novel Process Analytical Technology (PAT) Tools for Use in Freeze-Drying Processes Der Naturwissenschaftlichen Fakultät der Friedrich-Alexander-Universität Erlangen-Nürnberg zur Erlangung des Doktorgrades vorgelegt von Stefan Christian Schneid aus München Als Dissertation genehmigt von der Naturwissen- schaftlichen Fakultät der Universität Erlangen-Nürnberg Tag der mündlichen Prüfung: 8. 12. 2009 Vorsitzender der Promotionskomission: Prof. Dr. Eberhard Bänsch Erstberichterstatter: Prof. Dr. Geoffrey Lee Zweitberichterstatter: Prof. Dr. Gerhard Winter Dedicated to my parents The important thing in science is not so much to obtain new facts as to discover new ways of thinking about them. Sir William Bragg (1862 - 1942) Science is facts; just as houses are made of stones, so is science made of facts; but a pile of stones is not a house and a collection of facts is not necessarily science. Henri Poincare (1854 - 1912) Acknowledgements The research work presented in this thesis has been performed between April 2006 and April 2007 at the Department of Pharmaceutical Sciences, University of Connecticut, Storrs, USA, and between April 2007 and July 2009 at the Division of Pharmaceutics, University of Erlangen-Nuremberg, Erlangen, Germany.