Slow viruses in sheep, goats and cattle (In particular maedi visna, jaagsiekte, and in caprines, arthritis, encephalitis and pneumonitis)
380 pages
English
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380 pages
English
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Agricultural and fisheries research
Veterinary sector and animal health

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Nombre de lectures 65
Langue English
Poids de l'ouvrage 6 Mo

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Commission of the European Communities
AGRICULTURE
Slow viruses in sheep, goats and cattle
(In particular maedi visna, jaagsiekte, and in caprines,
arthritis, encephalitis and pneumonitis)
Report
EUR 8076 EN Commission of the European Communities
AGRICULTURE
Slow viruses in sheep, goats and cattle
(In particular maedi visna, jaagsiekte, and in caprines,
arthritis, encephalitis and pneumonitis)
Proceedings of two workshops, one held in Reykjavik (Iceland) on 13 and 14 July 1982,
the other in Edinburgh (Scotland) on 13 and 14 September 1983, sponsored by the
Commission of the European Communities, Directorate-General for Agriculture, as
part of the research programme on animal pathology
Edited by
J.M. Sharp
Animal Diseases Research Association
Moredun Institute
Edinburgh, United Kingdom
and
R. Hoff-Jørgensen
State Veterinary Serum Laboratory
Copenhagen, Denmark
Directorate-General for Agriculture f^H^kS^SÌSN
Coordination of Agricultural Research
1985 EUR 8076 EN Published by the
COMMISSION OF THE EUROPEAN COMMUNITIES
Directorate-General
Information Market and Innovation
Bâtiment Jean Monnet
LUXEMBOURG
LEGAL NOTICE
Neither the Commission of the European Communities nor any person acting on
' behalf of then is responsible for the use which might be made of the
following information
Cataloguing data can be found at the end of this publication
Luxembourg: Office for Official Publications of the European Communities, 1985
ISBN 92-825-5715-4
Catalogue number :^)-NK:85njl4:5tJ-B
© ECSC-EEC-EAEC, Brussels · Luxembourg, 1985
Printed in Luxembourg Preface
The concept of slow virus diseases originated from the work of Björn
Sigurdsson and his colleagues in the 1930's and they constitute an important
group of diseases of both veterinary and medical interest. The slow virus
diseases of sheep, maedi-visna and pulmonary adenomatasis, were two of the
originals which lead to the concept. Today, they continue to play an
important role in the sheep industrv by reducing the performance of affected
animals and creating barriers to international trade of animals. In addition,
together with caprine arthritis-encephalitis, they offer valuable animal
models of human diseases, the relevance of which is underlined by the recent
demonstration of the genetic relationship of maedi-visna virus and HTLV-III,
the causal agent of human acquired immune deficiency syndrome.
This publication has drawn together papers presented at two workshops on slow
virus diseases of sheep and goats held in Reykjavik, Iceland in July, 1982
and Edinburgh, Scotland in September, 1983. It is not the intention of this
publication to provide general reviews of these diseases, but rather to high­
light the current and future areas of interest and research. Over twenty
research groups attended the two meetings and their papers represent an up-
to-date compilation of current work on these diseases, ranging from studies
of the epidemiology and control strategies to molecular analysis of the
viruses.
It is the organizers hope that these workshops and this publication will
stimulate future work that will lead to a better understanding of the
patogenesis of slow virus infections and hereby enable us to create a
strategy for control and eradication of the infections.
J.M. SHARP. R- HOFF-JÍRGENSEN
- Ill -PART I
REYKJAVIK, 13-14 JULY 1982 CONTENTS
Page
Introduction ­ "aedi/visna of Sheep in Iceland, 3
Palsson, " . ¡\..
MAEDI­VISNA ­ STUDIES OF THE VIRUS
Antigenic variation of visna virus in relation to virus 2\
persistence and disease progression
Pétursson, Π.
Molecular Dioloqy of Maedi/visna Viruses 27
Vigne, P. et al.
strains of visna virus with increasedneurovirulence 45
Lutley, P. et al.
Comparative study of several strains ofMaedi/visna viruses ?1
Vigne, P.. et al .
Use of bacterial Plasmids containing the 'ÎSV­I tk gene 69
and c.'7 4Γ) early gene for cloning of Visna "irus Ρ?ΤΛ
Recher, Y.
MAEDI­VISNA ­ PATHOGENESIS ­IMMUNOLOGY
Interaction of American strains of Lentiviruses of Sheep 77
and goats with macrophages
Mara/an, 0.
experimental intra­articular maedi virus infection in Sheep S3
T.arsen, M.T.
MAEDI­VISNA TRANSMISSION AND DETECTION
transmission studies of Maedi/visna in Sheep 17
Straub, o.e.
A comparison of an indirect enzymze linkedimmunosorbent°3
assay, an indirect immunofluorescence testandanagar
gel immunodiffusion test for the detection of antibodies
to "laedi/visna virus in ovine sera
Dawson, '1. et al .
MAEDI­VISNA CONTROL AND ERADICATION
Slow virus diseases of the Sheep in Greece IOS
Soiraenis, Λ. et al.
Observations of the presence of visna/'"aediinfection 111
in Italy
Foglini, Λ. et al .
experimental Maedi/visna control in the Netherlands IIS
'Ouwers, P.T. et al.
­ VI ­page
Control programme for "aedi/Visna in Pelgiun 1?3
P.iront, ?. et al .
Maedi/visna infection in Prance
results of serological examinations and trialof 1">~l
erad leation
P.emond , M. et al .
Control programme For Lenti­virus infections in nanisn 133
sheep and goats
"of f—T(¿rgenson , Ρ .
Control of Maedi in Morway 1 so
Krogsrud, J.
CAPRINEARTHRITIS­ENCEPHALITIS VIPUS
Is CAS" a goat variant of ovine Maedi/"isna virus lis
Park, K. et al.
Comparison of Maedi/visna virus, caprine arthritis­\i.r>
encephalitis virus and goat retrovirus by blotting
technique
Pouwers, P. et al.
The presence of T.entivirus infections in Swiss goat herds 153
"wail len, P.
SHEEP PULMONARY ADENOMATOSIS
Sheep pulmonary adenomatosis in the Mnited States: 1 so
Tncidence and pathology
Cutlip, P.C.
Recent studies on the retrovirus etiology of sheep 1 (S3
pulmonary adenomatosis
Perk, X. et al.
Studies on the epidemioloay, aetiology and transmission 1G7
of jaagsiekte in Scotland
Sharp, J.M. et al .
­ VII

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