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Diagnostic Atlas of Renal Pathology, by Agnes B. Fogo, MD and Michael Kashgarian, MD, delivers practical, highly visual guidance for effectively and accurately diagnosing a wide range of pathologic entities. More than 700 high-quality illustrations help you to recognize the pathologic features and clinical manifestations of both common and rare renal disorders and to formulate confident and accurate diagnoses. Thoroughly updated throughout, this companion to Brenner & Rector’s The Kidney, 9th Edition provides the newest information regarding categorizing and classification of diseases and describes how this relates to the various morphological lesions illustrated and their clinical significance.

  • See more than 700 high quality representative images of light, immunofluorescence, and electron microscopy for each diagnostic entity with correlations to clinical presentation and pathogenesis.
  • Easily locate in-depth information on any disease's clinical course and treatment by cross-referring companion text, Brenner & Rector’s The Kidney.
  • Grasp key characteristic pathologic findings and prognostic, pathogenetic, and etiologic information through focused, detailed discussions.
  • Make accurate, complete reports by fully understanding clinical correlations.
  • Get an in-depth examination of pathophysiology, clinical presentations, and comprehensive references
  • Keep current with the latest knowledge and evidence-based practices. Comprehensive updates throughout include a brand-new chapter on "Approaches to Chronic Kidney Disease" that includes coverage of Chronic Kidney Disease; Age-Related Sclerosis; Glomerular vs. Tubulointerstitial vs. Vascular Disease; and the differential diagnostic approach to Segmental Glomerulosclerosis lesions. Extensive updates to all previous chapters include new classifications of various diseases such as igA nephropathy, diabetic nephropathy, crescentic GN, and renal transplant rejection.
  • Stay well informed about hot topics including acute phosphate nephropathy; new concepts in the pathogenesis of thrombotic microangiopathies and eclampsia; and new information relative to etiology and pathogenesis of podocytopathies.
  • Quickly access the information you need thanks to a user-friendly format, tables and sidebars with key points and differential diagnoses, and chapters that include concise, templated discussions regarding the etiology and pathogenesis of the disorder.



Publié par
Date de parution 29 septembre 2011
Nombre de lectures 1
EAN13 9781437737691
Langue English
Poids de l'ouvrage 18 Mo

Informations légales : prix de location à la page 0,0611€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.


Diagnostic Atlas of Renal Pathology
A Companion to Brenner & Rector’s The Kidney , 9th edition
Second Edition

Agnes B. Fogo, MD
John L. Shapiro Professor of Pathology, Professor of Medicine and Pediatrics, Director, Renal/Electron Microscopy Laboratory, Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee

Michael Kashgarian, MD
Professor Emeritus of Pathology and Molecular, Cellular, and Developmental Biology, Department of Pathology, Yale University, New Haven, Connecticut
Front Matter

Diagnostic Atlas of Renal Pathology, Second Edition
A Companion to Brenner & Rector’s The Kidney , 9th edition
Agnes B. Fogo , MD
John L. Shapiro Professor of Pathology
Professor of Medicine and Pediatrics
Director, Renal/Electron Microscopy Laboratory
Department of Pathology
Vanderbilt University Medical Center
Nashville, Tennessee
Michael Kashgarian , MD
Professor Emeritus of Pathology and
Molecular, Cellular, and Developmental Biology
Department of Pathology
Yale University
New Haven, Connecticut

1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
Diagnostic Atlas of Renal Pathology, Second Edition 978-1-4377-0427-3
Copyright © 2012, 2005 by Saunders, an imprint of Elsevier Inc.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions .
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Editors assumes any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book.
The Publisher
Library of Congress Cataloging-in-Publication Data
Fogo, Agnes B.
Diagnostic atlas of renal pathology : a companion to Brenner & Rector’s the Kidney / Agnes B. Fogo, Michael Kashgarian. – 2nd ed.
p. ; cm.
Companion v. to Brenner & Rector’s the kidney / edited by Barry M. Brenner. 8th ed. c2008.
Includes bibliographical references and index.
ISBN 978-1-4377-0427-3 (hardcover : alk. paper) 1.  Kidneys–Diseases–Atlases. I.  Kashgarian, Michael. II.  Brenner & Rector’s the kidney. III.  Title.
[DNLM: 1.  Kidney Diseases–diagnosis–Atlases. 2.  Kidney Diseases–pathology–Atlases. WJ 17]
RC903.F64 2012
Acquisitions Editor: Kate Dimock
Developmental Editor: Ann Ruzycka Anderson
Publishing Services Manager: Jeff Patterson
Project Manager: Tracey Schriefer
Design Direction: Lou Forgione
Printed in China
Last digit is the print number: 9  8  7  6  5  4  3  2  1
In the 5 years since our first edition was published, there have been many advances in the genetics, etiology, pathogenesis, and treatment of medical renal diseases. These advances have led to a therapeutic focus on a more specific and personalized approach and, in turn, further emphasized the importance and central role of the renal biopsy in patient management. We have taken these factors into consideration in organizing material for the second edition of this renal pathology companion book to the newest edition of Brenner and Rector’s The Kidney , edited by Taal et al. The organization of this edition follows that of the first, with each of the sections being expanded and updated to include new classifications of various kidney diseases, both native and transplant related. In addition, we have added a new chapter focusing on an approach to end-stage kidney disease as the prevention of progression of chronic renal disease has become an increasingly important goal in nephrology. Sections on genetics, etiology, and pathogenesis have also been expanded. References have been updated, and continue to be focused, rather than encyclopedic and comprehensive. These selected reading suggestions can act as a key to the greater detail present in the larger comprehensive text, The Kidney .
Because this is primarily an atlas, we have added numerous new images. These include illustrations of additional entities and expanded illustrations of the spectrum of lesions present in diseases already included in the previous edition. Two new features are tables of key diagnostic features of each of the entities and summaries of differential diagnoses. Together with the numerous images and focused text, this atlas thus provides in-depth and detailed illustrations of a large spectrum of morphologic lesions encountered in the renal biopsy and an approach to differential diagnosis and key prognostic, pathogenetic, and etiologic information.
Renal pathology is an exciting process of integrating complex information, relying on a team of nephrologists, pathologists, and highly skilled laboratory personnel. Similar teamwork has gone into the preparation of this book. The deep satisfaction derived from the first edition of our atlas, along with ongoing advances and realizations that we could further update and enhance our presentation of renal pathology in a usable and concise format, have led to this second edition. The ongoing dedication and partnership with Dr. Michael Kashgarian have been essential to the success of our project. I would also like to thank my renal pathology laboratory team, my fellows and colleagues, who have been essential for both the first edition and this second edition. I continue to be grateful to my past fellows, Drs. Paisit Paueksakon, Xochi Geiger, Patricia Revelo, and Michele Rossini, and my more recent fellows, Drs. Aruna Dash and Huma Fatima, who have searched and hunted for the most instructive and beautiful examples of lesions to expand this atlas. I am also indebted to the expert help of Brent Weedman for imaging and photography assistance.
Lastly, I would like to thank my husband, Byron, and my children, Katherine, Michelle, and Kristin, for their enthusiastic support and encouragement for all of my endeavors.

Agnes B. Fogo
This second edition follows our commitment to present medical renal pathology in a form that is accessible to a wide audience. We have used the lessons learned from the residents, fellows, and colleagues who have commented on our previous work in presenting the expansion of knowledge in this field. As such, it reflects a maturation of our discipline over the past 50 years that began with the contributions of the early pioneers of renal pathology, Robert Heptinstall, Conrad Pirani, Jacob Churg, Ben Spargo, and Robert McCluskey. I am indebted to the many clinical and pathology colleagues that I have had the pleasure of working with during these formative years of renal pathology. I would also like to dedicate this work to those who initially started me on the path of studying the kidney. Franklin Epstein was the first to introduce me to the wonders and complexity of the physiology of the kidney. Karl Ullrich taught me the scientific methods and tools necessary to investigate them. Averill Liebow inspired me to pursue pathology as a career. The field of renal pathology was in its infancy when I began my career, and it was the encouragement of these mentors and early pioneers in the field that kept me focused on this discipline. The expert help of my administrative assistant and the staffs of the Yale Pathology Graphics and Imaging and Histology sections was essential to the preparation of the images and the manuscript. Finally, I would like to thank my wife Jean for her patience and encouragement as I prepared this work.

Michael Kashgarian
Table of Contents
Front Matter
Chapter 1: Glomerular Diseases
Chapter 2: Vascular Diseases
Chapter 3: Tubulointerstitial Diseases
Chapter 4: Chronic Kidney Disease
Chapter 5: Renal Transplantation
Chapter 6: Cystic Diseases of the Kidney
Chapter 7: Renal Neoplasia
chapter 1 Glomerular Diseases

References to Brenner & Rector’s The Kidney 9th edition are given in parentheses below.
NORMAL GROWTH AND MATURATION 2 ( B&R ch. 1, p. 2-6; ch. 2, p. 31-84)

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