Hemodiafiltration - A New Era

Description

Hemodiafiltration (HDF) for the treatment of end-stage renal disease patients is predominantly performed in European countries and in Japan, with some differences in technique such as rate of blood flow and dialysis fluid delivery systems. The main focus of this book is on the clinical importance of online HDF, the techniques of which have been re-evaluated with the introduction of super high-flux membrane dialyzers. After a brief introduction into the history of HDF, recent advances and clinical experiences of HDF are summarized, including water quality control for dialysis fluid, equipped system for safe use, clinical advantages, and theoretical aspects of HDF. Moreover, at the end of each chapter researchers and scientists discuss problems into which further research is needed. Clinicians and scientists involved in the treatment of end-stage renal disease patients will find this publication an essential source of information. Moreover, it may also serve as a textbook for those who are planning to start HDF in their clinics or who are studying blood purification therapies in medical schools, nursing schools and even in engineering schools related to medical technologies.

Informations

• Publié par: S. Karger AG
• Date de parution: 06 octobre 2010
• Nombre de lectures: 0
• EAN13: 9783805595612
• Langue: English
• Poids de l'ouvrage: 3 Mo

Extrait

Hemodiafiltration - A New Era
Contributions to Nephrology
Vol. 168
Series Editor
Claudio Ronco     Vicenza
 
Hemodiafiltration – A New Era
Volume Editors
Hideki Kawanishi     Hiroshima
Akihiro C. Yamashita     Fujisawa
59 figures, 7 in color, and 21 tables, 2011
Contributions to Nephrology (Founded 1975 by Geoffrey M. Berlyne)
_________________________
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Hideki Kawanishi Tsuchiya General Hospital 3-30 Nakajima-cho, Naka-ku Hiroshima 730-8655 Japan
Akihiro C. Yamashita Department of Human and Environmental Science Shonan Institute of Technology 1-1-25 Tsujido-Nishikaigan Fujisawa, Kanagawa 251-8511 Japan
Library of Congress Cataloging-in-Publication Data
Hemodiafiltration:a new era/volume editors, Hideki Kawanishi, Akihiro C. Yamashita.
p.; cm. –– (Contributions to nephrology, ISSN 0302-5144; v. 168)
Includes bibliographical references and indexes.
ISBN 978-3-8055-9560-5 (hard cover: alk. paper) –– ISBN 978-3-8055-9561-2 (e-ISBN)
1. Hemodialysis. 2. Blood-Filtration. I. Kawanishi, Hideki. II. Yamashita, Akihiro C. III. Series: Contributions to nephrology; v. 168. 0302-5144
[DNLM: 1. Hemodiafiltration-methods. 2. Hemodiafiltration-instrumentation.3. Online Systems. W1 C0778UN v.168 2011/WJ378]
RC901.7.H446H46 2011
617.4'61059-dc22
2010033888
Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents® and Index Medicus.
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
© Copyright 2011 by S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland)
www.karger.com
Printed in Switzerland on acid-free and non-aging paper (ISO 9706) by Reinhardt Druck, Basel
ISSN 0302–5144
ISBN 978–3–8055–9560–5
e-ISBN 978–3–8055–9561–2
 
Contents
Preface
Kawanishi, H. (Hiroshima); Yamashita, A.C. (Fujisawa)
History and Evolution of Hemodiafiltration
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Dawn of Hemodiafiltration
Ota, K. (Tokyo)
Hemodiafiltration - State of the Art
Locatelli, F.; Manzoni, C.; Viganò, S.; Cavalli, A.; Di Filippo, S. (Lecco)
Hemodiafiltration: Evolution of a Technique towards Better Dialysis Care
Ronco, C. (Vicenza)
Clinical Benefits of Hemodiafiltration
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Optimal Therapeutic Conditions for Online Hemodiafiltration
Canaud, B.; Chenine, L.; Renaud, S.; Leray, H. (Montpellier)
Effect of Hemodiafiltration on Mortality, Inflammation and Quality of Life
den Hoedt, C.H. (Utrecht/Rotterdam); Mazairac, A.H.A. (Utrecht); van den Dorpel, M.A. (Rotterdam); Grooteman, M.P.C. (Amsterdam); Blankestijn, P.J. (Utrecht)
How to Prescribe Hemodialysis or Hemodiafiltration in Order to Ameliorate Dialysis-Related Symptoms and Complications
Masakane, I. (Yamagata)
Optimizing Home Dialysis: Role of Hemodiafiltration
Vilar, E.; Farrington, K. (Stevenage/Hatfield); Bates, C.; Mumford, C.; Greenwood, R. (Stevenage)
Management of Dialysis Fluid and Dialysis System
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Quality Management of Dialysis Fluid for Online Convective Therapies
Ward, R.A. (Louisville, Ky.)
Biocompatibility of Dialysis Fluid for Online HDF
Tomo, T. (Oita); Shinoda, T. (Tokyo)
Characteristics of Central Dialysis Fluid Delivery System and Single Patient Dialysis Machine for HDF
Aoike, I. (Niigata)
Fully Automated Dialysis System for Online Hemodiafiltration Built into the Central Dialysis Fluid Delivery System
Kawanishi, H.; Moriishi, M. (Hiroshima)
Uremic Toxins
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New Uremic Toxins-Which Solutes Should Be Removed?
Glorieux, G.; Vanholder, R. (Gent)
Beta-2-Microglobulin as a Uremic Toxin: the Japanese Experience
Fujimori, A. (Kobe)
Markers and Possible Uremic Toxins: Japanese Experiences
Kinugasa, E. (Yokohama)
Dialysis Membranes for Hemodiafiltration
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Biocompatibility of the Dialysis Membrane
Takemoto, Y.; Naganuma, T.; Yoshimura, R. (Osaka)
Choice of Dialyzers for HDF
Yamashita, A.C. (Fujisawa); Sakurai, K. (Sagamihara)
Estimation of Internal Filtration Flow Rate in High-Flux Dialyzers by Doppler Ultrasonography
Mineshima, M. (Tokyo)
Clinical Aspects of Hemodiafiltration
______________________
Management of Anemia by Convective Treatments
Locatelli, F.; Manzoni, C.; Del Vecchio, L.; Di Filippo, S.; Pontoriero, G.; Cavalli, A. (Lecco)
Clinical Evaluation Indices for Hemodialysis/Hemodiafiltration in Japan
Shinoda T. (Tokyo); Koda, Y. (Niigata)
Effect of Large-Size Dialysis Membrane and Hemofiltration/ Hemodiafiltration Methods on Long-Term Dialysis Patients
Tsuchida, K.; Minakuchi, J. (Tokushima City)
Who Needs Acetate-Free Biofiltration?
Kuno, T. (Tokyo)
Improvement of Autonomic Nervous Regulation by Blood Purification Therapy Using Acetate-Free Dialysis Fluid - Clinical Evaluation by Laser Doppler Flowmetry
Sato, T.;Taoka, M. (Nagoya); Miyahara, T. (Tokyo)
Preservation of Residual Renal Function with HDF
Hyodo, T. (Yokohama/Sagamihara); Koutoku, N. (Houfu)
Author Index
Subject Index
 
Preface
In Japan, the history of online hemodiafiltration (HDF) began in 1982 when it was first performed. However, its use has become widespread since 1990 following the development of an online HDF built-in central dialysis fluid delivery system. The Japanese Society for Hemodiafiltration (JSHDF) was established in 1995. Recently, a JSHDF meeting was held jointly with the Korean Society for Hemodiafiltration, and many clinicians from Asian countries participated.
The 55th Annual Meeting of the Japanese Society for Dialysis Therapy (55th JSDT) was held in Kobe, Japan, June 19-20, 2010, with over 16,000 participants. Both technological and clinical aspects of dialysis therapy for ESRD patients were discussed at the meeting. Two international symposia on HDF of the 55th JSDT were carried out with the titles ‘Clinical aspects of HDF - Who to apply HDF?’ and ‘Technical aspects of HDF - How to apply HDF?’ following the keynote lecture by Dr. Francesco Locatelli. The authors of this new book are either the speakers of these international symposia or key members of the JSHDF.
Currently the most commonly used dialyzers in Japanese hospitals are so-called ‘super’ high-flux dialyzers. In Japan, the definition super high-flux membrane dialyzer refers to a clearance of ß 2 -microglobulin ≥50 ml/min under a blood flow rate of 200 ml/min and a dialysis fluid flow rate of 500 ml/min. The present share of the market of such dialyzers is over 90%. The main focus of this book is the clinical importance of online HDF that has been re-evaluated on the commonly prescribed conditions with super high-flux membrane dialyzers. Moreover, although HDF has been carried out throughout the world, its clinical benefit has not yet been confirmed sufficiently enough. Therefore, evaluations of the clinical benefits of HDF are another focus as well as new technological developments.
In memory of the late Dr. Kazuo Ota, who served as the first President of the Japanese Society of Hemodiafiltration (1995-2009).
We would like to thank the authors and all the contributors for the enormous effort and the quality of their scientific chapters. We would also like to thank all those who made this publication possible and Karger Publishers for the outstanding editorial assistance.
Hideki Kawanishi , Hiroshima, Japan Akihiro C. Yamashita , Fujisawa, Japan
History and Evolution of Hemodiafiltration
Kawanishi H, Yamashita AC (eds): Hemodiafiltration – A New Era. Contrib Nephrol. Basel, Karger, 2011, vol 168, pp 1-4
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Dawn of Hemodiafiltration
Kazuo Ota
Tokyo Women's Medical University, Tokyo, Japan
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Abstract
A brief history of hemodialysis, hemofiltration and hemodiafiltration (HDF) is reviewed with special interest on the