Intracranial Gliomas Part III - Innovative Treatment Modalities

Description

At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology for management of gliomas are highlighted as well. Many of these methods have already demonstrated antitumor efficacy in clinical testing, whereas others are still under development. The materials presented in this book are mainly directed at clinicians treating patients with brain tumors, as well as clinical and basic researchers working in the field of neuro-oncology.

Informations

• Publié par: S. Karger AG
• Date de parution: 10 juillet 2018
• Nombre de lectures: 0
• EAN13: 9783318060638
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Intracranial Gliomas
Part III - Innovative Treatment Modalities
Progress in Neurological Surgery
Vol. 30
Intracranial Gliomas
Part I - Surgery
Vol. 31
Intracranial Gliomas
Part II - Adjuvant Therapy
Vol. 32
Intracranial Gliomas
Part III - Innovative Treatment Modalities
Series Editor
L. Dade Lunsford Pittsburgh, PA
 
Intracranial Gliomas
Part III - Innovative Treatment Modalities
Volume Editors
Mikhail F. Chernov Tokyo
Yoshihiro Muragaki Tokyo
Santosh Kesari Santa Monica, CA
Ian E. McCutcheon Houston, TX
33 figures, 22 in color, and 16 tables, 2018
_________________________ Mikhail F. Chernov, MD, DMedSci Faculty of Advanced Techno-Surgery and Department of Neurosurgery Tokyo Women s Medical University Tokyo, Japan
_________________________ Yoshihiro Muragaki, MD, PhD Faculty of Advanced Techno-Surgery and Department of Neurosurgery Tokyo Women s Medical University Tokyo, Japan
_________________________ Santosh Kesari, MD, PhD, FANA, FAAN John Wayne Cancer Institute Pacific Neuroscience Institute at Providence Saint John s Health Center Santa Monica, CA, USA
_________________________ Ian E. McCutcheon, MD, CM, FRCS(C), FACS Department of Neurosurgery The University of Texas MD Anderson Cancer Center Houston, TX, USA
Library of Congress Cataloging-in-Publication Data
Names: Chernov, Mikhail F., editor. | Muragaki, Yoshihiro, editor. | Kesari, Santosh, editor. | McCutcheon, Ian E., editor.
Title: Intracranial gliomas. Part I, Surgery / volume editors, Mikhail F. Chernov, Yoshihiro Muragaki, Santosh Kesari, Ian E. McCutcheon.
Other titles: Surgery | Progress in neurological surgery ; v. 30. 0079-6492
Description: Basel ; New York : Karger, 2018. | Series: Progress in neurological surgery, ISSN 0079-6492 ; vol. 30 | Includes bibliographical references and indexes.
Identifiers: LCCN 2017020659| ISBN 9783318060560 (hard cover : alk. paper) | ISBN 9783318060577 (electronic version)
Subjects: | MESH: Glioma--surgery
Classification: LCC RD662.5 | NLM QZ 380 | DDC 616.99/481059--dc23 LC record available at
https://lccn.loc.gov/2017020659
Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents and PubMed/MEDLINE.
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Copyright 2018 by S. Karger AG, P.O. Box, CH–4009 Basel (Switzerland)
www.karger.com
Printed on acid-free and non-aging paper (ISO 9706)
ISSN 0079–6492
e-ISSN 1662–3924
ISBN 978–3–318–06062–1
e-ISBN 978–3–318–06063–8
To my friends; with special thanks to Ms. Maria Tikhonova for her constant support and encouragement during my work with this book.
M.F. Chernov
To my colleagues, my mentors, and my family.
Y. Muragaki
To my family for supporting me in my academic endeavors and to my patients for providing hope.
S. Kesari
To my wife Melly, with love; and in memory of Samuel Hassenbusch, MD, neurosurgeon, scientist, and friend, who died too soon of the disease this book covers.
I.E. McCutcheon
 
Contents
Series Editor s Note
Lunsford, L.D. (Pittsburgh, PA)
Preface
Chernov, M.F., Muragaki, Y. (Tokyo); Kesari, S. (Santa Monica, CA); McCutcheon, I.E. (Houston, TX)
Photodynamic Therapy of Malignant Gliomas
Kaneko, S.; Fujimoto, S.; Yamaguchi, H.; Yamauchi, T.; Yoshimoto, T.; Tokuda, K. (Sapporo)
Laser-Induced Interstitial Thermotherapy of Gliomas
Karampelas, I.; Sloan, A.E. (Cleveland, OH)
Stereotactic Cryodestruction of Gliomas
Martynov, B.V.; Kholyavin, A.I.; Nizkovolos, V.B.; Parfenov, V.E.; Trufanov, G.E.; Svistov, D.V. (Saint Petersburg)
High-Intensity Focused Ultrasound Ablation Therapy of Gliomas
Alkins, R.D.; Mainprize, T.G. (Toronto, ON)
Boron Neutron Capture Therapy of Malignant Gliomas
Miyatake, S.-I.; Kawabata, S.; Hiramatsu, R.; Kuroiwa, T. (Osaka); Suzuki, M.; Ono, K. (Kyoto)
Proton and Carbon Ion Therapy of Intracranial Gliomas
Combs, S.E. (Munich)
Novel and Prospective Molecular Targets for Therapy of Intracranial Gliomas
Butowski, N. (San Francisco, CA)
Cytokine Therapy of Gliomas
Iwami, K. (Nagakute); Natsume, A.; Wakabayashi, T. (Nagoya)
Cell-Based Immunotherapy of Gliomas
Everson, R.G.; Antonios, J.P.; Liau, L.M. (Los Angeles, CA)
Vaccine Therapy of High-Grade Gliomas
Ishikawa, E. (Tsukuba); Muragaki, Y. (Tokyo); Yamamoto, T.; Ohno, T.; Matsumura, A. (Tsukuba)
Gene Therapy and Virotherapy of Gliomas
Kim, J.W.; Chang, A.L.; Kane, J.R.; Young, J.S.; Qiao, J.; Lesniak, M.S. (Chicago, IL)
Stem Cell Therapy of Gliomas
Parker Kerrigan, B.C.; Hossain, A.; Yamashita, S.; Lang, F.F. (Houston, TX)
Convection-Enhanced Delivery for Management of Malignant Gliomas
Prabhu, S.S. (Houston, TX)
Targeted Local Therapy for Management of Intracranial High-Grade Gliomas
Paldor, I.; Chaichana, K.L.; Brem, H.; Tyler, B.M. (Baltimore, MD)
Extracellular Vesicles as a Platform for Glioma Therapeutic Development
Santiago-Dieppa, D.R.; Gonda, D.D.; Cheung, V.J.; Steinberg, J.A.; Carter, B.S.; Chen, C.C. (La Jolla, CA)
Alternating Electric Fields Therapy for Malignant Gliomas: From Bench Observation to Clinical Reality
Wong, E.T. (Boston, MA/Lowell, MA); Lok, E.; Swanson, K.D. (Boston, MA)
Perspectives of Nanotechnology in the Management of Gliomas
Yoon, J.W. (Jacksonville, FL); Jiang, W. (Houston, TX); Rutka, J.T. (Toronto, ON); Huang, Y.; Kim, B.Y.S. (Jacksonville, FL)
Author Index
Subject Index
To learn more about Vols. 30 and 31 go to http://www.karger.com/BookSeries/Home/223949
Series Editor s Note
Intracranial Gliomas Part III - Innovative Treatment Modalities represents the final book of three-part series focused on the diagnosis, management, and options for additional treatment of a still perplexing problem. The two prior volumes have highlighted international opinions reflecting on the past and current strategies for gliomas-including surgery and adjuvant radiation and chemotherapy approaches. The keys to future successful care of our patients with these tumors lies in many directions. First, comes increasing vigilance and early detection. Pioneering neurosurgeon Patrick Kelly, prior chair of neurosurgery at New York University, once stated that every young adult in the world should have a 10 minute whole head T2-weighted MRI as a baseline view of their brain. Early detection may be a crucial element-but then we have to have the courage to act on our suspicions, get a diagnosis, and intervene immediately. Second, surgery will remain an important way to confirm the histology until we have better brain mapping tools that can reliably define the type and grade of the tumor. Third, the practical application of our still emerging molecular knowledge may open doors that can significantly improve prognosis using specific targeted agents that get to the tumor without damaging the brain or the body. My colleague Steve Haines, Chair Emeritus at Minnesota, once told me some years ago A difference to be a difference must make a difference. As we continue to develop new strategies, we must make sure that any innovation has merit. The future of glioma care will require further innovation and a willingness to prove each innovation has scientific value.
L. Dade Lunsford , MD, FACS, FAANS, Pittsburgh, PA
Preface
With this, the third of three consecutive volumes of Progress in Neurological Surgery devoted to current management of intracranial gliomas, we present to the medical community Part III, dedicated to innovative treatment modalities. At present most intracranial gliomas are considered incurable with current therapeutic strategies. As a result, ongoing investigations continue the search for new methods that may more effectively control tumor growth.
In the opening chapter Kaneko et al. discuss clinical applications of photodynamic therapy in the management of malignant brain tumors and share their extensive clinical experience with this technique. Thermotherapy of intracranial gliomas performed by means of hypert