Metabolic Syndrome and Obesity in Childhood and Adolescence
186 pages
English

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186 pages
English

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Description

Despite the fact that the prevalence of obesity in early childhood has been stable and is no longer increasing in many developed and industrialized countries, the incidence of both obesity and full-blown metabolic syndrome in children and adolescents is still very high. Obesity is a major disease burden in all societies and needs to be prevented early in life. New approaches are eagerly sought and absolutely necessary. This book presents a comprehensive and state-of-the-art summary of current and new knowledge in this critical field. Crucial issues such as nutrition and genetics are described in detail. In addition, new ideas such as e-health and the consequences of urban living conditions are explored. Last but not least, modern treatment concepts and prevention even at an early age are competently discussed. Offering a valuable update on new developments in obesity research and the treatment in children and adolescents, this book is essential reading for all pediatricians and health-care professionals who look after young patients on a regular basis.

Informations

Publié par
Date de parution 27 janvier 2015
Nombre de lectures 0
EAN13 9783318027990
Langue English
Poids de l'ouvrage 2 Mo

Informations légales : prix de location à la page 0,0570€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

Extrait

Metabolic Syndrome and Obesity in Childhood and Adolescence
Pediatric and Adolescent Medicine
Vol.19
Series Editor
Wieland Kiess Leipzig
Metabolic Syndrome and Obesity in Childhood and Adolescence
Volume Editors
Wieland Kiess Leipzig
Martin Wabitsch Ulm
Claudio Maffeis Verona
Arya M. Sharma Edmonton, Alta.
28 figures, 18 in color, 9 tables, 2015
Pediatric and Adolescent Medicine Founded 1991 by D. Branski, Jerusalem
_______________________ Prof. Wieland Kiess, MD Department of Women and Child Health Hospital for Children and Adolescents University of Leipzig, Leipzig, Germany
_______________________ Prof. Martin Wabitsch, MD, PhD Interdisciplinary Obesity Unit Division of Pediatric Endocrinology and Diabetes Department of Pediatrics and Adolescent Medicine University Medical Center Ulm University of Ulm, Ulm, Germany
_______________________ Prof. Claudio Maffeis, MD Pediatric Diabetes, Clinical Nutrition and Obesity Department of Life and Reproduction Science School of Medicine and Surgery University of Verona, Verona, Italy
_______________________ Prof. Arya M. Sharma, MD, PhD, DSc. (h.c.), FRCPC Obesity Research and Management Division of Endocrinology Department of Medicine Faculty of Medicine and Dentistry University of Alberta, Edmonton, Alta., Canada
Library of Congress Cataloging-in-Publication Data
Metabolic syndrome and obesity in childhood and adolescence / volume editors, Wieland Kiess, Martin Wabitsch, Claudio Maffeis, Arya M. Sharma.
p.; cm. –– (Pediatric and adolescent medicine, ISSN 1017-5989; vol. 19)
Includes bibliographical references and indexes.
ISBN 978-3-318-02798-3 (hard cover: alk. paper) –– ISBN 978-3-318-02799-0 (electronic version)
I. Kiess, W. (Wieland), editor. II. Wabitsch, Martin, editor. III. Maffeis, Claudio, editor. IV. Sharma, Arya M., editor. V. Series: Pediatric and adolescent medicine; v. 19.1017-5989
[DNLM: 1. Pediatric Obesity. 2. Adolescent. 3. Child. 4. Metabolic Syndrome X. W1 PE163HL v. 19 2015/WS 115]
RJ399.C6
618.92'39––dc23
2014044095
Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents ® .
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
© Copyright 2015 by S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland)
www.karger.com
Printed in Germany on acid-free and non-aging paper (ISO 9706) by Kraft Druck GmbH, Ettlingen
ISSN 1017-5989
e-ISSN 1662-3886
ISBN 978-3-318-02798-3
e-ISBN 978-3-318-02799-0
Contents
Preface
Kiess, W. (Leipzig); Wabitsch, M. (Ulm); Maffeis, C. (Verona); Sharma, A.M. (Edmonton, Alta.)
Definitions and Clinical Aspects
Definitions
Wabitsch, M. (Ulm); Körner, A. (Leipzig)
Hypothalamic Obesity in Children
Bereket, A. (Istanbul); Kiess, W. (Leipzig); Lustig, R.H. (San Francisco, Calif.); Muller, H.L. (Oldenburg); Goldstone, A.P. (London); Weiss, R. (Jerusalem); Yavuz, Y. (Istanbul); Hochberg, Z. (Haifa)
Causes
Genetics of Obesity in Childhood and Adolescence
Böttcher, Y.; Kovacs, P. (Leipzig)
Nutrition
Kalhoff, H. (Dortmund); Kersting, M. (Bonn)
Sedentary Lifestyle
Raupp, A.; Jouret, B.;Tauber, M. (Toulouse)
Socio-Economic Aspects
Plachta-Danielzik, S.; Müller, M.J. (Kiel)
Consequences
Carbohydrate Metabolism
Wabitsch, M.; Denzer, C. (Ulm)
Orthopaedic Aspects of Obesity in Children and Adults
Thielemann, F.; Guenther, K.-P.; Stiehler, M. (Dresden)
Urogenital Complications: Renal Disease, Urolithiasis and Lower Urinary Tract Symptoms
Morandi, A.; Maffeis, C. (Verona)
Influences of Childhood Obesity on Pubertal Development
Wagner, I.V. (Leipzig); Sabin, M. (Parkville, Vic.); Kiess, W. (Leipzig)
Societal Aspects and Prevention
Urban Living Conditions: The Relation between Neighborhood Characteristics and Obesity in Children and Adolescents
Igel, U.; Grande, G. (Leipzig)
Metabolic Syndrome and the ‘Western Diet’: Science and Politics
Lustig, R.H. (San Francisco, Calif.)
An Economic Perspective on Childhood Obesity
Teuner, C.M.; John, J.; Wolfenstetter, S.B.; Holle, R. (Munich)
Prevention of Childhood and Adolescent Obesity and its Barriers
Markert, J. (Leipzig)
E-Health in Overweight and Obesity Prevention
Herget, S. (Leipzig)
Obesity Management
Obesity Treatment Programmes
Reinehr, T. (Datteln)
Adolescent Bariatric Surgery: Current Status in an Evolving Field
Luca, P. (Calgary, Alb.); Dettmer, E.; Langer, J.C.; Hamilton, J.K. (Toronto, Ont.)
Beyond Weight Loss: Experiences and Insights Related to Working Effectively with Families and Operating within the Health Care System to Manage Pediatric Obesity
Ball, G.D.C.; Avis, J.L.S. (Edmonton, Alta.); Buchholz, A. (Ottawa, Ont.); Bridger, T. (St. John's, Nfld.);Chanoine, J.-P. (Vancouver, B.C.); Hadjiyannakis, S. (Ottawa, Ont.); Hamilton, J.K. (Toronto, Ont.); Legault, L. (Montreal, Que.); Morrison, K.M. (Hamilton, Ont.); Wareham, A. (St. John's, Nfld.); Jetha, M.M. (Edmonton, Alta.)
Author Index
Subject Index
Preface
In this volume in our series ‘Pediatric and Adolescent Medicine,’ probably the most common and most urgent clinical problem in pediatrics and adolescent medicine is being covered by experts from around the world. The volume discusses pertinent and prevalent topics such as the definition and clinical aspects of obesity. Additionally, novel viewpoints and ideas for the future are presented; these will facilitate both interaction with obese children and adolescents in a fair and appropriate way and collaboration with the individuals affected to seek appropriate and effective prevention and treatment measures.
In section number one, definitions and clinical aspects are covered. Martin Wabitsch from the University of Ulm, Germany, and Antje Körner from the University of Leipzig, Germany, discuss different definitions and the basic clinical aspects of obesity in childhood and adolescence. They describe obesity as part of metabolic syndrome and indeed as one of the causes leading to the full-blown clinical picture of metabolic syndrome. Abdullah Bereket from Istanbul, Turkey, and his co-workers report on the following in their chapter on the clinical entity of hypothalamic obesity: obesity caused by injury or trauma to or surgery on the hypothalamus as well as the fact that inborn genetic diseases affecting nuclei and regions of the hypothalamus can cause obesity in a very severe and extreme way. Abdullah Bereket and his colleagues emphasize that hypothalamic obesity is still resistant to traditional therapeutic measures, that prevention should be mandatory but is also difficult, and that new clinical trials with new treatment protocols are urgently required.
In section two, Yvonne Böttcher and Peter Kovacs from the University of Leipzig, Germany, first present a very nicely written chapter on the genetics of obesity in childhood and adolescence. They focus on DNA and methylation and the biology of the disease. Second, Hermann Kalhoff and Mathilde Kersting from Dortmund and Bonn, Germany, outline all aspects of nutrition in relation to metabolic syndrome and obesity in childhood and adolescence. Third, sedentary behavior has been identified as a public health issue for the last 10 years. This is being pointed out in the excellent chapter from France, in which Maïthé Tauber and her colleagues from Toulouse rightly argue that preventive interventions should focus on changing the sedentary lifestyle, even and especially at a young age. In this fine contribution they also report on why people adopt a sedentary lifestyle. Fourth, Sandra Plachta-Danielzik and Manfred James Müller from the University of Kiel, Germany, review their own data and perform a meta-analysis of all available information on socio-economic aspects as causes of metabolic syndrome and obesity. It is actually their contribution via the ‘KOPS’ study in Kiel that has drawn our attention to the socio-economic aspects of metabolic syndrome during the last decade.
In section three, the consequences of

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