New Treatments in Noninfectious Uveitis

Description

Uveitis is a potentially blinding inflammatory disease that presents one of the most serious and complicated therapeutic challenges in the field of ophthalmology. During the last decade, the therapeutic armamentarium of the uveitis specialist has enormously expanded. Novel biologic agents and intraocular therapy are becoming a valuable alternative treatment to control ocular inflammatory diseases and inflammatory macular edema -- the most important cause of visual loss in patients with uveitis. This publication is designed to bring together the principles of therapy of patients with noninfectious uveitis and the most recent therapeutic options available. General ophthalmologists, uveitis specialists as well as residents will find it a useful update on the latest innovative treatment options for patients with noninfectious uveitis.

Informations

• Publié par: S. Karger AG
• Date de parution: 20 avril 2012
• Nombre de lectures: 0
• EAN13: 9783805599870
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

New Treatments in Noninfectious Uveitis
Developments in Ophthalmology
Vol.51
Series Editor
F. Bandello     Milan
 
New Treatments in Noninfectious Uveitis
Volume Editors
Elisabetta Miserocchi     Milan
Giulio Modorati     Milan
C. Stephen Foster     Cambridge, Mass.
14 figures, 8 in color, and 24 tables, 2012
_________________________
__________________________
Elisabetta Miserocchi Ocular Immunology and Uveitis Service Department of Ophthalmology and Visual Sciences Scientific Institute San Raffaele University Vita-Salute Via Olgettina 60 IT-20132 Milan (Italy)
Giulio Modorati Ocular Immunology and Uveitis Service Department of Ophthalmology and Visual Sciences Scientific Institute San Raffaele University Vita-Salute Via Olgettina 60 IT-20132 Milan (Italy)
_________________________
C. Stephen Foster Massachusetts Eye Research and Surgery Institution Ocular Immunology and Uveitis Foundation 5 Cambridge Center, 8th Floor Cambridge, MA 02142 (USA)
This book was generously supported by
 
Library of Congress Cataloging-in-Publication Data
New treatments in noninfectious uveitis / volume editors, Elisabetta Miserocchi, Giulio Modorati, C. Stephen Foster.
p.; cm. - (Developments in ophthalmology, ISSN 0250-3751 ; v. 51)
Includes bibliographical references and index.
ISBN 978-3-8055-9986-3 (hard cover: alk. paper) - ISBN 978-3-8055-9987-0 (e-ISBN)
I. Miserocchi, Elisabetta. II. Modorati, Giulio. III. Foster, C. Stephen (Charles Stephen), 1942- IV. Series: Developments in ophthalmology; v. 51. 0250-3751
[DNLM: 1. Uveitis-drug therapy. W1 DE998NG v.51 2012 / WW 240]
617.7'2-dc23
2012004581
Bibliographic Indices. This publication is listed in bibliographic services, including Current Contents® and Index Medicus.
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
© Copyright 2012 by S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland)
www.karger.com
Printed in Germany on acid-free and non-aging paper (ISO 9706) by Kraft Druck GmbH, Ettlingen
ISSN 0250-3751
e-ISSN 1662-2790
ISBN 978-3-8055-9986-3
e-ISBN 978-3-8055-9987-0
 
Contents
List of Contributors
Preface
Miserocchi, E.; Modorati, G. (Milan); Foster, C.S. (Cambridge, Mass.)
The Philosophy of Treatment of Uveitis: Past, Present and Future
Kruh, J.; Foster, C.S. (Cambridge, Mass.)
The Gold Standard of Noninfectious Uveitis: Corticosteroids
LeHoang, P. (Paris)
Corticosteroid-Sparing Agents: Conventional Systemic Immunosuppressants
Kruh, J.; Foster, C.S. (Cambridge, Mass.)
Corticosteroid-Sparing Agents: New Treatment Options
Tomkins-Netzer, O.; Taylor, S.R.J.; Lightman, S. (Guildford/London)
Mycophenolate Mofetil Use in the Treatment of Noninfectious Uveitis
Klisovic, D.D. (Dublin, Ohio)
Anti-Tumor Necrosis Factor-a Agents in Noninfectious Uveitis
Gueudry, J. (Rouen); LeHoang, P.; Bodaghi, B. (Paris)
New Biologic Drugs: Anti-Interleukin Therapy
Tappeiner, C.; Möller, B. (Bern); Hennig, M.; Heiligenhaus, A. (Münster/Essen)
Interferon-a Therapy in Noninfectious Uveitis
Deuter, C. (Tübingen); Stübiger, N. (Berlin); Zierhut, M. (Tübingen)
Rituximab for Noninfectious Uveitis
Miserocchi, E.; Modorati, G. (Milan)
Intravitreal Injection Therapy in the Treatment of Noninfectious Uveitis
Modorati, G.; Miserocchi, E. (Milan)
Corticosteroid Intravitreal Implants
de Smet, M.D. (Lausanne/Amsterdam)
New Treatment Options for Noninfectious Uveitis
Gomes Bittencourt, M.; Sepah, Y.J.; Do, D.V.; Agbedia, O.; Akhtar, A.; Liu, H.; Akhlaq, A.; Annam, R.; Ibrahim, M.; Nguyen, Q.D. (Baltimore, Md.)
Subject Index
 
List of Contributors
Owhofasa Agbedia
Retinal Imaging Research and Reading Center
Wilmer Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee 745
Baltimore, MD 21287 (USA)
E-mail [e-mail]
Anam Akhlaq
Retinal Imaging Research and Reading Center Wilmer
Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee 745
Baltimore, MD 21287 (USA)
E-mail [e-mail]
Abeer Akhtar
Retinal Imaging Research and Reading Center Wilmer
Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee 745
Baltimore, MD 21287 (USA)
E-mail [e-mail]
Rachel Annam
Retinal Imaging Research and Reading Center Wilmer
Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee 745
Baltimore, MD 21287 (USA)
E-mail [e-mail]
Millena Gomes Bittencourt
Retinal Imaging Research and Reading Center Wilmer
Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee 745
Baltimore, MD 21287 (USA)
E-mail [e-mail]
Bahram Bodaghi
Department of Ophthalmology
University of Paris VI
Pitié-Salpêtrière Hospital
47 Boulevard de L'Hôpital
FR-75013 Paris (France)
E-mail [e-mail]
Marc D. de Smet
Chemin des Allinges 10
CH-1001 Lausanne (Switzerland)
E-mail [e-mail]
Christoph Deuter
Centre for Ophthalmology
University of Tübingen
Schleichstrasse 12-16
DE-72076 Tübingen (Germany)
E-mail [e-mail]
Diana V. Do
Retinal Imaging Research and Reading Center
Wilmer Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee 745
Baltimore, MD 21287 (USA)
E-mail [e-mail]
C. Stephen Foster
Massachusetts Eye Research and Surgery Institution
Ocular Immunology and Uveitis Foundation
5 Cambridge Center, 8th Floor
Cambridge, MA 02142 (USA)
E-mail [e-mail]
Julie Gueudry
Department of Ophthalmology
Charles Nicolle University Hospital
1 rue de Germont
FR-76031 Rouen (France)
E-mail [e-mail]
Arnd Heiligenhaus
Department of Ophthalmology
St. Franziskus Hospital Hohenzollernring 74 DE-48145 Münster (Germany)
E-mail [e-mail]
Maren Hennig
Department of Ophthalmology
St. Franziskus Hospital
Hohenzollernring 74
DE-48145 Münster (Germany)
E-mail [e-mail]
Mohamed Ibrahim
Retinal Imaging Research and Reading Center
Wilmer Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee
745 Baltimore, MD 21287 (USA)
E-mail [e-mail]
Dino D. Klisovic
Midwest Retina
6655 Post Road
Dublin, OH 43016 (USA)
E-mail [e-mail]
Jonathan Kruh
Massachusetts Eye Research and Surgery Institution
Ocular Immunology and Uveitis Foundation
5 Cambridge Center, 8th Floor
Cambridge, MA 02142 (USA)
E-mail [e-mail]
Phuc LeHoang
Department of Ophthalmology
University of Paris VI
Pitié-Salpêtrière Hospital
83 Boulevard de L'Hôspital
FR-75013 Paris (France)
E-mail [e-mail]
Sue Lightman
UCL Institute of Ophthalmology
Moorfields Eye Hospital
162 City Road
London EC1V 2PD (UK)
E-mail [e-mail]
Hongting Liu
Retinal Imaging Research and Reading Center
Wilmer Eye Institute
Johns Hopkins University School of Medicine
600 North Wolfe Street, Maumenee
745 Baltimore, MD 21287 (USA)
E-mail [e-mail]
Elisabetta Miserocchi
Ocular Immunology and Uveitis Service
Department of Ophthalmology and Visual Sciences
Scientific Institute San Raffaele
University Vita-Salute
Via Olgettina 60
IT-20132 Milan (Italy)
E-mail [e-mail]
Giulio