Obstetric and Gynecologic Dermatology E-Book , livre ebook

OBSTETRIC AND GYNECOLOGIC DERMATOLOGY
Third Edition

Martin Black, MD FRCP FRCPATH
Emeritus Professor of Dermatological, Immunopathology and Honorary, Consultant Dermatologist, St. John's Institute of Dermatology, St. Thomas's Hospital, London, UK

Christina M. Ambros-Rudolph, MD
Associate Professor, Department of Dermatology, Medical University of Graz, Graz, Austria

Libby Edwards, MD
Associate Professor of Dermatology, University of North Carolina, Chapel Hill; Chief of Dermatology, Carolinas Medical Center Mid-Charlotte Dermatology and Research, Charlotte, North Carolina, USA

Peter J. Lynch, MD
Program Director and Frederick G. Novy, Jr., Professor of Dermatology, Department of Dermatology, University of California, Davis, Sacramento, California, USA
MOSBY
Front Matter

Obstetric and Gynecologic Dermatology
Third Edition
MARTIN BLACK, MD FRCP FRCPATH
Emeritus Professor of Dermatological, Immunopathology and Honorary, Consultant Dermatologist, St. John's Institute of Dermatology, St. Thomas's Hospital, London, UK
CHRISTINA M. AMBROS-RUDOLPH MD
Associate Professor, Department of Dermatology, Medical University of Graz, Graz, Austria
LIBBY EDWARDS MD
Associate Professor of Dermatology, University of North Carolina, Chapel Hill; Chief of Dermatology, Carolinas Medical Center Mid-Charlotte Dermatology and Research, Charlotte, North Carolina, USA
PETER J. LYNCH MD
Program Director and Frederick G. Novy, Jr., Professor of Dermatology, Department of Dermatology, University of California, Davis, Sacramento, California, USA
Copyright
MOSBY an imprint of Elsevier Limited
© 2008, Elsevier Limited. All rights reserved.
First published 2008
For revised editions, replace line above with publication years of previous editions e.g.:
First edition 1995
Second edition 2002
The right of Martin Black, Christina Ambros-Rudolph, Libby Edwards & Peter J. Lynch to be identified as authors of this work has been asserted by him/her/them in accordance with the Copyright, Designs and Patents Act 1988.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier's Rights Department: phone: (+1) 215 239 3804 (US) or (+44) 1865 843830 (UK); fax: (+44) 1865 853333; e-mail: healthpermissions@elsevier.com . You may also complete your request on-line via the Elsevier website at http://www.elsevier.com/permissions .
ISBN: 978-0-7234-3445-0
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
Library of Congress Cataloging in Publication Data
A catalog record for this book is available from the Library of Congress

Notice
Medical knowledge is constantly changing. Standard safety precautions must be followed, but as new research and clinical experience broaden our knowledge, changes in treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current product information provided by the manufacturer of each drug to be administered to verify the recommended dose, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on experience and knowledge of the patient, to determine dosages and the best treatment for each individual patient. Neither the Publisher nor the author_assume any liability for any injury and/or damage to persons or property arising from this publication.
The Publisher
Commissioning Editor: Thu Nguyen/Claire Bonnett
Development Editor: Sarah Penny
Project Manager: Kathryn Mason
Design: Stewart Larkin
Illustration Manager: Merlyn Harvey
Illustrator: Merlyn Harvey and Cactus
Marketing Managers (USA/UK): Todd Liebel/Clara Toombs


Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Preface
The first and second editions of this text, which we believe was the first ever to focus specifically on the full range of dermatologic problems encountered in obstetric and gynaecological practice, were very well received. For the third edition all chapters have been thoroughly updated and each presents a basic, sensible approach to a complex subject. We are particularly fortunate to have been able to recruit two eminent dermatologists who have long specialised in vulval dermatoses: Dr. Peter Lynch and
Dr. Libby Edwards have brought their considerable expertise together and have completely updated and largely re-written the sections on vulval dermatoses and tumours. All sections are profusely illustrated presenting numerous examples of common and unusual disorders or presentations. It is intended that the format of the illustrations and text will aid the user in comparing images of similar-appearing skin problems encountered in the clinic or office.
Further emphasis is also made in the text on practical suggestions for diagnostic approaches as well as outlining detailed and practical suggestions for therapy.
In addition I am grateful that my co-worker Dr. Christina Ambros-Rudolph has been able to join us as a co-editor and that Dr. Samantha Vaughan Jones has continued to work closely with us.
We believe that this atlas and detailed text will continue to be appreciated by consulting dermatologists and non-dermatologists alike. In particular we feel that this book will continue to be a useful reference for all clinicians who care about women's health.

Martin M. Black

Christina Ambros-Rudolph

Peter Lynch

Libby Edwards
List of Contributors

Christina M. Ambros-Rudolph, MD, Associate Professor of Dermatology and Venereology, Department of Dermatology, Medical University of Graz, Graz, Austria

Martin M. Black, MD FRCP FRCPath, Emeritus Professor of Dermatological Immunopathology, Honorary Consultant Dermatologist, St. John's Institute of Dermatology, St. Thomas's Hospital, London, UK

Peter R. Braude, PhD FRCOG F Medsci, Professor of Obstetrics & Gynecology, Chairman & Head of Department, United Medical & Dental Schools of Guy's & St. Thomas's Hospital, London, UK

Libby Edwards, MD, Associate Professor of Dermatology University of North Carolina, Chapel Hill; Chief of Dermatology, Carolinas Medical Center, Mid-Charlotte Dermatology and Research, Charlotte, NC, USA

Emma Fox, FRCP, Consultant Virologist, Department of Infection, Guy's and St. Thomas’ NHS Foundation Trust, Guy's Hospital, London, UK

Hope K. Haefner, MD, Professor, Department of Obstetrics and Gynecology, The University of Michigan Hospitals, Ann Arbor, MI, USA

Diana Hamilton-Fairley, MD FRCOG, Joint Head of Women's Health Services Delivery Unit, Guy's and St. Thomas’ NHS Foundation Trust, St. Thomas’ Hospital, London, UK

Rachel E. Jenkins, BSc MD FRCP, Consultant Dermatologist, Dermatology Department, West Suffolk Hospital, Bury St Edmonds, Suffolk, UK

Diana N.J. Lockwood, BSc MD FRCP, Consultant Physician & Leprologist, Hospital for Tropical Diseases, Copper Street, London, UK

Peter J. Lynch, MD, Program Director and Frederick G. Novy, Jr. Professor of Dermatology, Department of Dermatology, University of California, Davis, Sacramento, CA, USA

Eithne MacMahon, MD FRCPI MRCPath, Consultant in Infectious Diseases and Virology, Department of Infectious Diseases and Virology, St. Thomas’ Hospital, London, UK

Lynette Margesson, MD, Assistant Professor, Division of Dermatology, Queens University, Kingston, ON, Canada

Catherine Nelson-Piercy, MA FRCP MB BSc FRCOG, Consultant Obstetric Physician, Women's Health Services Directorate, St. Thomas' Hospital, London, UK

Daghni Rajasingham, MBBS MRCOG, Consultant Obstetrician, Women's Health Services Directorate, St. Thomas’ Hospital, London, UK

Jeff K. Shornick, MD MHA, Private Practice, Groton, CT, USA

Catherine J.M. Stephens, MBBS FRCP, Consultant Dermatologist, Poole Hospital NHS Trust, Poole, Dorset, UK

Samantha Vaughan-Jones, MD FRCP, Consultant Dermatologist, Department of Dermatology, Ashford and St. Peter's NHS Trust, Chertsey, Surrey, UK
Dedications
To my wife, Aniko.
M.B.
To my family for encouraging me to go into medicine and to my husband, Johannes, for his love and continuing support.
C.A.-R.
To my wonderful niece, Amanda Coombs.
L.E.
I would like to express my gratitude to Eduard G. Friederich, Jr., Raymond W. Kaufman, and Donald J. Woodruff. Their role in helping me to understand genital disease in women cannot be overestimated. They have in addition served as valued colleagues, important mentors, and warm friends.
P.L.
Table of Contents
Front Matter
Copyright
Preface
List of Contributors
Dedication
Part 1: Obstetrics
Chapter 1: Hormonal Changes during Puberty, Pregnancy, and the Menopause
Chapter 2: Perimenstrual Skin Eruptions, Autoimmune Progesterone Dermatitis, Autoimmune Estrogen Dermatitis
Chapter 3: Physiologic Skin Changes of Pregnancy
Chapter 4: A Systematic Approach to the Dermatoses of Pregnancy
Chapter 5: Pemphigoid (Herpes) Gestationis
Chapter 6: Polymorphic Eruption of Pregnancy
Chapter 7: Intrahepatic Cholestasis of Pregnancy
Chapter 8: Atopic Eruption of Pregnancy