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Swaiman’s Pediatric Neurology, by Drs. Kenneth Swaiman, Stephen Ashwal, Donna Ferriero, and Nina Schor, is a trusted resource in clinical pediatric neurology with comprehensive, authoritative, and clearly-written guidance. Extensively updated to reflect advancements in the field, this fifth edition covers new imaging modalities such as pediatric neuroimaging, spinal fluid examination, neurophysiology, as well as the treatment and management of epilepsy, ADHD, infections of the nervous system, and more. The fully searchable text is now available online at www.expertconsult.com, along with downloadable images and procedural videos demonstrating intraventricular hemorrhage and white matter injury, making this an indispensable multimedia resource in pediatric neurology.

  • Gain a clear visual understanding from the numerous illustrations, informative line drawings, and summary tables.
  • Tap into the expertise of an authoritative and respected team of editors and contributors.
  • Get comprehensive coverage of all aspects of pediatric neurology with a clinical focus useful for both the experienced clinician and the physician-in-training.
  • Access the fully searchable text online at www.expertconsult.com, along with 16 additional online-only chapters, downloadable images, videos demonstrating intraventricular hemorrhage and white matter injury, and links to PubMed.
  • Stay current on recent developments through extensive revisions: a new chapter on paraneoplastic syndromes in children; a new section on congenital brain malformations written by leading international authorities; and another one on cutting-edge pediatric neuroscience concepts relating to plasticity, neurodegeneration of the developing brain, and neuroinflammation.
  • Apply the latest information on diagnostic modalities, including pediatric neuroimaging, spinal fluid examination, and neurophysiology


Brain Death
Miastenia gravis
Genoma mitocondrial
Epilepsy in children
Metabolic myopathy
Mental retardation
Viral disease
Organic acidemia
Guillain?Barré syndrome
Paraneoplastic syndrome
Tonic?clonic seizure
Dihydrolipoamide dehydrogenase
Generalised epilepsy
Chromosome abnormality
Peroxisomal disorder
Anterior horn of spinal cord
Neurological examination
West syndrome
Temporal lobe epilepsy
Neurodevelopmental disorder
Arachnoid cyst
Partial seizure
Tic disorder
Neurofibromatosis type II
Agenesis of the corpus callosum
Visual impairment
Gait abnormality
Status epilepticus
Medical history
Sensorineural hearing loss
Traumatic brain injury
Spinal cord injury
Hyperkalemic periodic paralysis
Degenerative disease
Duchenne muscular dystrophy
Congenital heart defect
Ketogenic diet
Subdural hematoma
Subarachnoid hemorrhage
Neuromuscular junction
Prenatal diagnosis
Peripheral neuropathy
Tuberous sclerosis
Lysosomal storage disease
Intracranial pressure
Pain management
Carbohydrate metabolism
Absence seizure
Lumbar puncture
Congenital disorder
Palliative care
Cerebrovascular disease
Neural tube
Neural development
Physical exercise
Glycogen storage disease
Mitochondrial disease
Motor neuron
Febrile seizure
Medical ultrasonography
Heart disease
Cardiopulmonary resuscitation
Attention deficit hyperactivity disorder
Cardiac arrest
Tourette syndrome
Rett syndrome
Ménière's disease
Clinical neurophysiology
Mood disorder
X-ray computed tomography
Cerebral palsy
Multiple sclerosis
Hearing impairment
Sleep disorder
Brain tumor
White matter
Epileptic seizure
Nervous system
Magnetic resonance imaging
Muscular dystrophy
Genetic disorder
Major depressive disorder
Down syndrome
Cerebrospinal fluid
Bipolar disorder


Publié par
Date de parution 11 novembre 2011
Nombre de lectures 0
EAN13 9780323089111
Langue English
Poids de l'ouvrage 36 Mo

Informations légales : prix de location à la page 0,1612€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.


Swaiman’s Pediatric Neurology
Principles and Practice Volume 1
Fifth Edition

Kenneth F. Swaiman, MD
Director Emeritus, Division of Pediatric Neurology
Professor Emeritus of Neurology and Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA

Stephen Ashwal, MD
Distinguished Professor of Pediatrics, Chief of the Division of Child Neurology and Pediatrics, Loma Linda University School of Medicine, Loma Linda, CA, USA

Donna M. Ferriero, MD MS
W.H. and Marie Wattis Distinguished Professor and Chair Department of Pediatrics Physician-in-Chief UCSF Benioff Children’s Hospital University of California San Francisco San Francisco, CA, USA

Nina F. Schor, MD
William H. Eilinger Chair of Pediatrics, Professor, Departments of Pediatrics, Neurology, and Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA
Front matter
Swaiman’s Pediatric Neurology
Commissioning Editor: Lotta Kryhl
Development Editor: Janice Gaillard
Editorial Assistant: Emma Cole
Project Manager: Frances Affleck
Design: Kirsteen Wright
Illustration Manager: Karen Giacomucci
Illustrator: Dartmouth Publishing and Joe Chovan
Marketing Manager (UK/USA): Gaynor Jones/Helena Mutak

Swaiman’s Pediatric Neurology

Principles and Practice
Volume 1
Kenneth F. Swaiman MD , Director Emeritus, Division of Pediatric Neurology Professor Emeritus of Neurology and Pediatrics University of Minnesota Medical School Minneapolis, MN, USA
Stephen Ashwal MD , Distinguished Professor of Pediatrics Chief of the Division of Child Neurology and Pediatrics Loma Linda University School of Medicine Loma Linda, CA, USA
Donna M. Ferriero MD MS , W.H. and Marie Wattis Distinguished Professor and Chair Department of Pediatrics Physician-in-Chief UCSF Benioff Children's Hospital University of California San Francisco San Francisco, CA, USA
Nina F. Schor MD PhD , William H. Eilinger Chair of Pediatrics Professor, Departments of Pediatrics, Neurology, and Neurobiology and Anatomy University of Rochester School of Medicine and Dentistry Rochester, NY, USA
With pleasure and appreciation we dedicate this book to our spouses, Phyllis Sher, Eileen Ashwal, Thomas Rando, and Robert Schor, who made it possible for us to spend the enormous amount of time planning, reading, and editing that was necessary to bring this text to fruition. It is impossible to describe the value of their encouragement and support adequately.
Furthermore, no dedication of a book embracing this field would be meaningful without a tribute to the courage and perseverance of neurologically impaired children and their caretakers.

SAUNDERS is an imprint of Elsevier Inc.
© 2012, Elsevier Inc. All rights reserved.
First edition 1989
Second edition 1994
Third edition 1999
Fourth edition 2006
Fifth edition 2012
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher's permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions .
This book and the individual contributions contained in it are protected under copyright by the Publisher.

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
British Library Cataloguing in Publication Data
Swaiman's pediatric neurology. -- 5th ed.
1. Pediatric neurology.
I. Ashwal, Stephen, 1945- II. Swaiman, Kenneth F., 1931-
III. Pediatric neurology.
ISBN-13: 9781437704358
Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Preface to the First Edition
It is concurrently tiring, humiliating, and intellectually revitalizing to compile a book containing the essence of the information that embraces one’s life work and professional preoccupation. For me, there is a certain moth-to-the-flame phenomenon that cannot be resisted; therefore this new book has been produced.
Pediatric neurology has come of age since my initial interest and subsequent immersion in the field. Concentrated attention to the details of brain development and function has brought much progress and understanding. Studies of disease processes by dedicated and intelligent individuals accompanied by a cascade of new technology (e.g., neuroimaging techniques, positron emission tomography, DNA probes, synthesis of gene products, sophisticated lipid chemistry) have propelled the field forward. The simultaneous increase of knowledge and capability of pediatric neurologists and others who diagnose and treat children with nervous system dysfunction has been extremely gratifying.
Although once within the realm of honest delusion of a seemingly sane (but unrealistic) devotee of the field, it is no longer possible to believe that a single individual can fathom, much less explore, the innumerable rivulets that coalesce to form the river of knowledge that currently is pediatric neurology. Streams of information in certain areas sometimes peacefully meander for years; suddenly, when knowledge of previously obscure areas is advanced and the newly gained information becomes central to understanding basic pathophysiologic entities, a once small stream gains momentum and abruptly flows with torrential force.
This text is an attempt to gather the most important aspects of current pediatric neurology and display them in a comprehensible manner. The task, although consuming great energies and concentration, cannot be accomplished completely because new conditions are described daily.
The advancement of the field necessitated that preparation of this text keep pace with current knowledge and present new and valuable techniques. My colleagues and I have made every effort to discharge this responsibility. Because of continuous scientific progress, controversies are extant in some areas for varying periods; wherever possible, these areas of conflict are indicated.
This book is divided into four unequal parts. Part I contains a discussion of the historic and clinical examination. Part II contains information concerning laboratory examination. Chapters relating to the symptom complexes that often reflect the chief complaints of neurologically impaired children compose Part III. Part IV provides detailed discussion of various neurologic diseases that afflict children.
Although every precaution has been taken to avoid error, bias, and prejudice, inevitably some of these demons have become embedded in the text. The editor assumes full responsibility for these indiscretions.
It is my fervent hope that the reader will find this book informative and stimulating and that the contents will provide an introduction to the understanding of many of the conditions that remain mysterious and poorly explained.

Kenneth F. Swaiman, MD
Autumn 1988
Preface to the Fifth Edition
Since publication in 2006 of the fourth edition of Pediatric Neurology: Principles & Practice , the discipline of child neurology has progressed and reached new levels of complexity. Advances in molecular biology and neuroimaging have fueled an explosion of knowledge that has translated into a richer understanding of nervous system development and function. Researchers and clinicians alike believe that, during the next decade, novel and targeted treatments will be the product of such fundamental advances in knowledge. Successful treatment of children with both common and rare neurologic disorders is becoming a reality.
This fifth edition reflects the enormous growth and intricacy of the basic and clinical neurosciences. The entire text has been revised and reorganized. Many chapters have undergone extensive updating, as they reflect clinical areas of child neurology that are bec

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