Translational Medicine - What, Why and How: An International Perspective

Description

This book is the first to provide an aerial view, as well as detailed information, on ‘how’ activities in translational medicine are under development in countries such as the USA, China, the UK, and Taiwan. Institutions in each country are training investigators to work as sophisticated interdisciplinary teams. Investigators from 11 US academic health centers explain how they are incentivizing collaborations through pilot project programs, forming partnerships with business schools to promote efficient management of basic and clinical research, creating ethical, high-value public-private (industry) partnerships, improving efficiency with utilization of informatics, and engaging the community in research. The essential role of evaluation is explained in a clear and concise manner. The readers will also learn about the role of private funding in Taiwan and the vision of the government in China in developing multiple translational research centers. The UK is developing methodical approaches to patient needs across their lifespans; ongoing innovation is encouraged through incubator programs. With the emphasis on open innovation and sharing, the concepts and practice of translational medicine are spreading rapidly on an international scale.

Informations

• Publié par: S. Karger AG
• Date de parution: 21 décembre 2012
• Nombre de lectures: 0
• EAN13: 9783318022858
• Langue: English
• Poids de l'ouvrage: 1 Mo

Extrait

Translational Medicine – What, Why and How: An International Perspective
Translational Research in Biomedicine
Vol.3
Series Editor
Samuel H.H. Chan Kaohsiung
Associate Editor
Julie Y.H.Chan Kaohsiung
Translational Medicine – What, Why and How: An International Perspective
Volume Editors
Barbara Alving Bethesda, Md.
Kerong Dai Shanghai
Samuel H.H.Chan Kaohsiung
14 figures, 7 in color, and 14 tables, 2013
___________________________
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Barbara Alving, MD Uniformed Services University of the Health Sciences 7118 Glenbrook Road Bethesda, MD 20814 (USA)
Kerong Dai, MD Clinical Translational Center of Stem Cell and Regenerative Medicine Ninth People's Hospital Shanghai Jiao Tong University School of Medicine Shanghai (China)
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Samuel H.H. Chan, PhD Center for Translational Research in Biomedical Sciences Kaohsiung Chang Gung Memorial Hospital 123, Taipei Road Kaohsiung 83801(Taiwan)


The Chang Gung Medical Foundation is the patron of this book series.
Library of Congress Cataloging-in-Publication Data
Translational medicine: what, why, and how: an international perspective / volume editors, Barbara Alving, Kerong Dai, Samuel H.H. Chan.
p.; cm. –– (Translational research in biomedicine, ISSN 1662-405X ; v. 3)
Includes bibliographical references and indexes.
ISBN 978-3-318-02284-1 (hard cover: alk. paper) –– ISBN 978-3-318-02285-8 (electronic version)
I. Alving, Barbara M. II. Dai, Kerong. III. Chan, Samuel H. H. IV. Series: Translational research in biomedicine ; v. 3. 1662-405X
[DNLM: 1. Translational Medical Research. 2. Academic Medical Centers––trends. W 20.55.T7]

610.72––dc23
2012041085
Disclaimer. The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publisher and the editor(s). The appearance of advertisements in the book is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Drug Dosage. The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
© Copyright 2013 by S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland)
www.karger.com
Printed in Switzerland on acid-free and non-aging paper (ISO 9706) by Reinhardt Druck, Basel
ISSN 1662–405X
e-ISSN 1662–4068
ISBN 978–3–318–02284–1
e-ISBN 978–3–318–02285–8
Contents
Foreword
Chan, S.H.H. (Kaohsiung)
Preface
Alving, B. (Bethesda, Md.); Dai, K. (Shanghai); Chan, S.H.H. (Kaohsiung)

The What and Why of Translational Medicine
Alving, B. (Bethesda, Md.); Dai, K. (Shanghai); Chan, S.H.H. (Kaohsiung)
Partnership Model for Academic Health Science Systems to Address the Continuum from Discovery to Care, at Scale
Fish, D.; Chantler, C.; Kakkar, A.K.; Trembath, R.; Tooke, J. (London); on behalf of UCLPartners
The US Initiative: Clinical and Translational Science Awards - The UC Davis Perspective
Tarantal, A.F.; Rainwater, J.; Wun, T.; Berglund, L. (Sacramento, Calif.)
National Agenda and Strategies for the Development and Implementation of Translational Medicine
Zhao, Y. (Beijing)
Developing a Translational Research Workforce in the USA
Pearson, T.A. (Rochester, N.Y.); Kapoor,W.N. (Pittsburgh, Pa.); Holloway, R.G. (Rochester, N.Y.)
Training Translational Investigators in China
Shi, T.Z. (Catonsville, Md.); Dai, K. (Shanghai)
Translational Medicine in Taiwan: The Role of Private Foundation Funding
Chan, S.H.H. (Kaohsiung)
Utilizing Pilot Funding and Other Incentives to Stimulate Interdisciplinary Research
Denne, S.C.; Sajdyk,T. (Indianapolis, Ind.);Sorkness, C.A.; Drezner, M.K. (Madison, Wisc.); Shekhar, A. (Indianapolis, Ind.)
Building Expertise in Translational Processes through Partnerships with Schools of Business
Cheng, S.K.; Dilts, D.M. (Portland, Oreg.)
Creating Ethical, High-Value Industry-Academic Partnerships
Steele, S. (Rochester, N.Y.); Holroyd, K.J. (Nashville, Tenn.); Fadem, T.J. (Philadelphia, Pa.)
Increasing the Efficiency and Quality of Clinical Research with Innovative Services and Informatics Tools
Disis, M.L.; Tarczy-Hornoch, P.; Ramsey, B.W. (Seattle, Wash.)
Engaging the Community in Research with the HealthStreet Model: National and International Perspectives
Cottler, L.B.; Striley, C.W. (Gainesville, Fla.); O'Leary, C.C. (St. Louis, Mo.); Ruktanonchai, C.W. (Gainesville, Fla.); Wilhelm, K.A. (Darlinghurst, New South Wales)
Evaluating Translational Research
Kane, C. (Ithaca, N.Y.); Rubio, D. (Pittsburg, Pa.);Trochim, W. (Ithaca, N.Y.)
Envisioning the Future of Translational Medicine: A Snapshot of 2016
Alving, B. (Bethesda, Md.); Dai, K. (Shanghai); Chan, S.H.H. (Kaohsiung)

Author Index
Subject Index
Foreword
Welcome to volume 3 of Translational Research in Biomedicine, a monograph series dedicated to the dissemination of seminal information in contemporary biomedicine with a translational orientation. This volume marks a new milestone of this series. Beginning with this volume, Translational Research in Biomedicine will be published under the generous patronage of Chang Gung Medical Foundation, Taiwan. This patronage will reduce substantially the increasing financial constraints on scientific publication, and allow us to concentrate on publishing timely and crucial themes in translational medicine.
This volume is designed to be a key reference for translational medicine. During the last decade, translational medicine has become a household word in the arena of medical research and beyond. Closer scrutiny, however, has revealed that the term ‘translational medicine’ has been interpreted and presented widely, ranging from pure rhetoric in political orations, golden geese to entrepreneurs or shareholders, to conscientious solutions to health issues. My personal view is that this multiplicity arises from the lack of a comprehensive overview on the ‘what’, ‘why’, and ‘how’ aspects of translational medicine. This volume is designed to fill this void based on an international perspective.
I wish to express my deepest appreciation to Drs. Barbara Alving and Kerong Dai, whose patience and sustaining efforts have made this timely volume, Translational Medicine - What, Why and How: An International Perspective, a reality. Last but not least, the publication of Translational Research in Biomedicine would not have been possible without the foresight, enthusiasm, and whole-hearted support of my dear friend, Dr. Thomas Karger.
Samuel H.H. Chan, Kaohsiung
Series Editor
Preface
Although translational medicine is now a common term throughout the scientific world, a comprehensive monograph that addresses the ‘what’, ‘why’, and ‘how’ aspects of translational medicine, particularly from an international perspective, has not been forthcoming. This volume will fill this void. Fourteen chapters written by eminent experts with diversified experience will address three general themes: ‘What is translational medicine?’, ‘Why do governments, research institutions, and other organizations invest in translational medicine?’, and ‘How is translational medicine carried out internationally?’. In so doing, it is our intention to make this volume a key reference of translational medicine.
Our sincere thanks go to the authors who have kindly consented to contribute their expert opinion to this volume and to Chang Gung Medical Foundation in Taiwan for sponsoring the Translational Research in Biomedicine series.
Barbara Alving, Bethesda, Md.
Kerong Dai, Shanghai
Samuel H.H. Chan, Kaohsiung
Volume Editors
 
Alving B, Dai K, Chan SHH (eds): Translational Medicine - What, Why and How: An International Perspective. Transl Res Biomed. Basel, Karger, 2013, vol 3, pp 1-5 (DOI: 10.1159/000343146)
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The What and Why of Translational Medicine
Barbara Alving a Kerong Dai b Samuel H.H. Chan c
a Uniformed Services, University of the Health Sciences, Bethesda, Md., USA; b Clinical Translational Center of Stem Cell and Regenerative Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; c Center for Translational Research in Biomedical Sciences, Chang Gung M