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979 pages
English

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Description

Tumors and Tumor-like Conditions of the Lung and Pleura is a superb visual resource that brings the state-of-the-art in thoracic diagnosis straight to the lab bench. Cesar A. Moran and Saul Suster are internationally recognized experts in pulmonary pathology who present a coherent and consistent approach to interpretation and diagnosis. Through more than 900 stunning photographs and a consistent, user-friendly format, this resource provides quality guidance on the diagnostic problems you face in everyday practice. You’ll get a host of innovative, practice-oriented features unavailable in any other text that streamline and facilitate diagnostic decision-making. Written by practitioners for practitioners, this visual resource is designed for quick and easy use. You can’t afford to be without it.

  • Features over 900 high-quality full-color illustrations so you can recognize and diagnose any tissue sample under the microscope.
  • Presents immunohistochemical and genetic features wherever relevant for comprehensive information on all of the investigative contexts important to formulating an accurate diagnosis.
  • Includes summary tables throughout the text to simplify and clarify complex discussions and enable "at a glance" comparisons between entities.
  • Provides practical advice from experts on pitfalls in differential diagnosis to help you avoid diagnostic errors.

Sujets

Informations

Publié par
Date de parution 22 mars 2010
Nombre de lectures 0
EAN13 9781455705504
Langue English
Poids de l'ouvrage 4 Mo

Informations légales : prix de location à la page 0,0514€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

Extrait

Tumors and Tumor-like Conditions of the Lung and Pleura

Cesar A. Moran, MD
Professor and Deputy Chair, Director of Thoracic Pathology, Department of Pathology, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas

Saul Suster, MD
Professor and Chairman, Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin
Elsevier Inc., 2010
Saunders
Front matter
Tumors and Tumor-like Conditions of the Lung and Pleura

Tumors and Tumor-like Conditions of the Lung and Pleura
CESAR A. MORAN, MD , Professor and Deputy Chair, Director of Thoracic Pathology, Department of Pathology, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas
SAUL SUSTER, MD , Professor and Chairman, Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin
Copyright

TUMORS AND TUMOR-LIKE CONDITIONS OF THE LUNG AND PLEURA
ISBN: 978-1-4160-3624-1
Copyright © 2010 by Elsevier Inc.
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier’s Rights Department: phone: (+1) 215 239 3804 (U.S.) or (+44) 1865 843830 (U.K.); fax: (+44) 1865 853333; e-mail: healthpermissions@elsevier.com You may also complete your request on-line via the Elsevier Web site at http://www.elsevier.com/permissions .


Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Library of Congress Cataloging-in-Publication Data
Moran, Cesar.
Tumors and tumor-like conditions of the lung and pleura / Cesar A. Moran, Saul Suster.—1st ed.
p. ; cm.
Includes bibliographical references.
ISBN 978-1-4160-3624-1
1. Lungs—Tumors. 2. Lungs—Pleura. I. Suster, Saul. II. Title.
[DNLM: 1. Lung Neoplasms—diagnosis. 2. Diagnostic Imaging—methods. 3. Pleural Neoplasms—diagnosis. WF 658 M829t 2010]
RC280.L8M625 2010
616.99’424—dc22
2010001329
Publishing Director: Bill Schmitt
Developmental Editor: Katie DeFrancesco
Project Manager: David Saltzberg
Design Direction: Lou Forgione
Printed in the United States
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Dedication
To our families Susan, Jenny, Elisa Jean, Dana, Kate, and David for their continuous support
Contributors

Edith M. Marom, MD, Professor of Diagnostic Radiology, Department of Diagnostic Imaging, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Chapter 1 : Imaging Tumors of the Lung and Pleura

David J. Stewart, MD, Professor and Deputy Chair, Department of Thoracic and Head and Neck Oncology, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Chapter 14 : Clinical Management of Lung Cancer

Garrett L. Walsh, MD, Professor of Surgery, Department of Thoracic Surgery, The University of Texas, M. D. Anderson Cancer Center, Houston, Texas
Chapter 2 : Staging of Thoracic Malignancies: A Surgeon’s Perspective
Preface

Cesar A. Moran, MD, Saul Suster, MD
This textbook gives surgical pathologists a practical approach to the diagnosis of the different tumors and tumor-like conditions that may affect the lung and pleura. The book has been arranged and subdivided based on the different families of tumors that may seed those structures. When important, historical background is provided so that the surgical pathologist becomes more familiar with the different terminologies used over the years. Current concepts and definitions are also presented so that their importance and the difficulties they may pose to the surgical pathologist are apparent. The text focuses on the morphologic approach to the different tumoral conditions and the use of ancillary methods to corroborate the morphologic diagnosis. When appropriate, important advanced studies, such as molecular pathology information, are also provided.
Additionally, the text provides important radiologic, surgical, and oncologic information that must be considered when dealing with the different conditions presented. In presenting these components, which are essential to understanding the pathology of the lung and pleura, we are indebted to Edith Marom, MD, for her contribution on diagnostic imaging; Garrett L. Walsh, MD, for his contribution on surgical staging, and to David J. Stewart, MD, for his contribution on the clinical management of lung cancer. They provide important information that is of great benefit to all involved in the diagnosis and treatment of patients with lung and/or pleural lesions.
This textbook will be useful not only to surgical pathologists but also to oncologists, surgeons, and radiologists who want to get better acquainted with the diverse histologies that may be present in the lung and pleura. Additionally, we hope this text enhances communication among all the different specialties involved in the treatment of patients with tumors of the lung and pleura.
Table of Contents
Front matter
Copyright
Dedication
Contributors
Preface
Chapter 1: Imaging Tumors of the Lung and Pleura
Chapter 2: Staging of Thoracic Malignancies: A Surgeon’s Perspective
Chapter 3: Non–Small Cell Carcinomas of the Lung
Chapter 4: Salivary Gland–Type Tumors of the Lung
Chapter 5: Neuroendocrine Tumors of the Lung
Chapter 6: Biphasic Tumors of the Lung
Chapter 7: Mesenchymal Tumors of the Lung
Chapter 8: Vascular Tumors of the Lung
Chapter 9: Lung Tumors Derived from Presumed Ectopic Tissues
Chapter 10: Lymphoproliferative Tumors of the Lung
Chapter 11: Lung Tumors of Uncertain Histogenesis
Chapter 12: Benign Tumors and Tumor-like Lesions of the Lung
Chapter 13: Tumors of the Pleura
Chapter 14: Clinical Management of Lung Cancer
Chapter 15: Handling and Grossing of Larger Cases
Index
1 Imaging Tumors of the Lung and Pleura

Edith M. Marom

Primary Malignant Lung Tumors
Screening
Early Detection: Solitary Pulmonary Nodule
Imaging of Lung Cancer Subtypes
Staging
Follow-up Evaluation
Uncommon Primary Pulmonary Malignancies
Secondary Malignant Lung Tumors
Primary Malignant Pleural Tumors
Mesothelioma
Localized Fibrous Tumor of the Pleura
Secondary Malignant Pleural Tumors
Conclusions
In the past few decades, the use of computers has revolutionized imaging, with the introduction of technologies such as computed tomography (CT), magnetic resonance imaging (MRI), ultrasonography, positron emission tomography (PET), and, more recently, PET-CT, which integrates anatomic (morphologic) and physiologic aspects of imaging. With the ever-greater subspecialization of the different areas of practice within medical oncology—surgical oncology, radiation oncology, and diagnostic radiology—and the expanding use of picture archiving systems, radiologist and clinician may encounter each other only rarely, if at all. Optimal patient outcomes, however, require careful planning of imaging for diagnosis, staging, and follow-up, best achieved through direct communication between the clinician and the radiologist. This chapter presents a general overview of lung and pleural tumor imaging, with an emphasis on the strengths and weaknesses of specific techniques in evaluating different tumor types, to help in selection of the ideal imaging modality for each patient.

PRIMARY MALIGNANT LUNG TUMORS

Screening
Despite new diagnostic techniques, the overall 5-year survival rate for patients with lung cancer, the leading cause of cancer death, remains approximately 15%, and most patients still present with advanced disease. 1 This high death rate is presumed to reflect a combination of difficulty in detecting early-stage disease and lack of significant curative treatment. Abrogating cigarette smoking would be highly effective in reducing the prevalence of lung cancer but would not abolish it altogether, because effecting

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