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Chronic Total Occlusions

256 pages
Chronic total occlusions (CTO) are common, and found in approximately one third of patients with significant coronary artery disease who undergo angiography. Over the past 20 years, CTO lesions have represented the most difficult anatomy for treatment — with lower success rates and higher complication rates.

Chronic Total Occlusions provides interventionalists insight into the world of CTOs with introductory chapters that describe the pathology and indications of CTOs along with a review of clinical trials. Imaging modalities including CT angiography, magnetic navigation wire, and IVUS guided recanalization of CTO are also introduced, together with information on new wires technology and devices for CTOs.

With numerous illustrations of these devices, technologies, and strategies to improve the CTO success rate, this clinical guide, headed up by Ron Waksman, will prove to be the ideal companion for interventional cardiologists and cardiac surgeons who are required to perform angioplasty and coronary stenting.

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Contributors, vii Preface, ix Foreword, x
Part I Pathology and Indications: Clinical Trials, 1
1 3The Pathobiology of CTO, Ronen Jaffe, MD, Brian Courtney, MD, & Bradley H. Strauss, MD, PhD
2 8Indication and Outcome of PCI for CTO, Ron Waksman, MD, FACC
3 4CTO – Review of Trials, 1 Tina L. Pinto Slottow, MD & Ron Waksman, MD, FACC
Part II Imaging, 23 4 CT Angiography: Application in Chronic Total Occlusions, 25 Hidehiko Hara, MD, John R. Lesser, MD, Nicholas Burke, MD, & Robert S. Schwartz, MD 5 2Magnetic Navigation Wire, 3 Steve Ramcharitar, BMBCh, DPhil & Patrick Serruys, MD, PhD 6 8IVUS-Guided Recanalization of CTO, 3 Etsuo Tsuchikane, MD, PhD
Part III Wires Technology, 43
7 5Deflecting Tip Wires, 4 Mirko Schiemann, MD
8 0ASAHI Wires, 5 Shigeru Saito, MD, FACC, FSCAI, FJCC
9 7Tornus Catheter, 5 Hideaki Kaneda, MD, PhD 10 Introduction of a New 0.014-inch CiTop™ Guidewire for CTO: Preclinical Safety and Feasibility Studies, 62 Mickey Scheinowitz, PhD 11 0Frontrunner CTO Technology, 7 Chad Kliger, MD, Steven P. Sedlis, MD, FACC, FSCAI, & Jeffrey D. Lorin, MD, FACC
Part IV Wires Technique, 75 12 Use of Two Wires in the Treatment of CTO, 77 Thierry Lefèvre, MD, FESC, FSCAI, Yves Louvard, MD, FSCAI, & Marie-Claude Morice, MD, FACC, FESC 13 3Parallel-Wire Techniques, 8 Jean-François Surmely, MD & Takahiko Suzuki, MD 14 7Wire Control Handling Technique, 8 Shigeru Saito, MD, FACC, FSCAI, FJCC
15 3Subintimal Angioplasty, 9 Masashi Kimura, MD, PhD, Antonio Colombo, MD, Eugenia Nikolsky, MD, PhD, Etsuo Tsuchikane, MD, PhD, & George Dangas, MD, PhD
16 4Re-entry Technique – Pioneer Catheter, 10 Nicolaus Reifart, MD, PhD, FESC, FACC, RANS
17 7Bilateral Approach, 10 Jean-François Surmely, MD & Osamu Katoh, MD
18 3Tips and Tricks of the CART Technique, 11 Osamu Katoh, MD
Part V Devices Technology, 121
19 3Radio Frequency, 12 Richard Heuser, MD, FACC, FACP, FESC
20 High-Frequency Mechanical Revascularization, 136 Eberhard Grube, MD & Lutz Buellesfeld, MD
21 0Debulking of CTO, 14 Etsuo Tsuchikane, MD, PhD
22 5Vibrational Angioplasty, 14 Lampros K. Michalis, MD, MRCP, FESC
23 0Drug-Eluting Stents, 15 David E. Kandzari, MD
24 9Laser for CTO Recanalization, 15 On Topaz, MD
Part VI Complications, 165
25 7How to Handle Complications, 16 Axel de Labriolle, MD & Ron Waksman, MD
26 8How to Minimize Contrast Nephropathy, 17 Robin Mathews, MD & Luis Gruberg, MD, FACC
Part VII Interesting Cases, 187
27 9Interesting Cases I, II, 18 Takafumi Tsuji, MD & Hideo Tamai, MD Index, 195 Colour plates appear between p. 86 and p. 87