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Intracranial Atherosclerosis

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272 pages
Intracranial atherosclerosis is the dominant cause of stroke in over 70% of the world’s population. Globalization is leading to an increasingly heterogeneous society everywhere. Advances in imaging techinology allow this previously inaccessible pathology to be clinically studied.



Edited by internationally renowned clinicians, Intracranial Atherosclerosis is the first book to examine intracranial causes of stroke. Clinical practice is allied with basic science to guide all those with an interest in stroke on the diagnosis and management of intracranial atherosclerosis.

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Contents
List of contributors, vii Preface, xi Foreward, xiii
Epidemiology and risk factors 1 Anatomy of intracranial arteries, 3 David S Liebeskind and Louis R Caplan 2 Pathologic characteristics, 19 XiangYan Chen and Mark Fisher 3 Epidemiology, 33 Philip Gorelick, Jinghao Han, Yining Huang and KS Lawrence Wong 4 Risk factors, 45 Kazuo Minematsu, Oh Young Bang and Toshiyuki Uehara
Stroke mechanism and clinical consequence 5 Stroke mechanisms, 57 KS Lawrence Wong, Louis R Caplan and Jong S Kim 6 Anterior circulation disorders, 69 Jong S Kim 7 Posterior circulation disorders, 83 Louis R Caplan, Pierre Amarenco and Jong S. Kim 8 Cognitive dysfunction, dementia and emotional disturbances, 100 JaeHong Lee, Alex E Roher, Thomas G Beach and Jong S Kim 9 Natural course and prognosis, 113 Juan F Arenillas, Louis R Caplan and KS Lawrence Wong
Diagnostic imaging studies 10 Vascular imaging, 127 Edward Feldman, Harry J Cloft, Mai NguyenHuynh and Avean McLaughlin 11 Application of magnetic resonance imaging, 135 DongWha Kang and Jong S Kim 12 Transcranial doppler, 147 Qing Hao, KS Lawrence Wong and Andrei V Alexandrov
v
C O N T E N T S
vi
Treatment 13 Antiplatelet therapy, 163 Sun U Kwon and Jong S Kim 14 Anticoagulation, 173 Fadi B Nahab and Marc I Chimowitz 15 Angioplasty and stenting, 181 WeiJian Jiang, Dae Chul Suh, Yongjun Wang and Thomas W Leung 16 Surgical therapy, 194 Chang Wan Oh and Jeong Eun Kim 17 Other miscellaneous treatments, 206 Christopher Chen, Jinghao Han and KS Lawrence Wong
Uncommon causes of intracranial arterial disease 18 Immunologic and vasoconstrictive disorders, 217 Min Lou and Louis R. Caplan 19 Arterial dissection, CNS infection and other miscellaneous diseases, 229 JiannShing Jeng and Jong S Kim 20 Moyamoya disease, 246 Susumu Miyamoto, Jun C. Takahashi and Jong S. Kim
Index, 259 Colour plates, 160