Cardiovascular Disease, An Issue of Clinics in Perinatology

Shannon E. G. Hamrick, Nikhil K. Chanani

Description

The impact of cardiovascular disease on an infant extends from the fetal period to well beyond childhood. Perinatalogists and neonatologists can impact maternal and fetal health through wide range of diagnostic modalities and interventional techniques. For our edition focused on cardiovascular health, we sought to encompass the breadth of knowledge that would be the most relevant for the bed side clinician. Our goal was to assemble contents that would allow a clinician to quickly peruse the journal, and then be prepared to make a medical decision. The interaction between cardiology and perinatology/neonatology includes genetics, diagnostics, interventions, counseling, routine stabilization and day to day care. Ultimately, the goal is to establish the foundation for a healthy adult. For this reason, we have even included chapters on topics that are significant on a day to day basis (such as the proper environment for a newborn) and a long term basis (like the overall neurodevelopmental impact of our interventions). Hopefully, whether in the middle of the night as an emergency reference or during the day as a reliable guide, this edition of Clinics in perinatology will be an important bedside tool for anyone that participates in the care of a patient with perinatal heart disease.

Sujets

• Médecine
• Spécialités médicales
• Gynécologie et Obstétrique
• Médecine Générale
• Gynecology
• Medical
• Obstetrics

Informations

• Publié par: Elsevier
• Date de parution: 27 février 2016
• Nombre de lectures: 0
• EAN13: 9780323416580
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Cardiovascular Disease
Clinics in Perinatology
Editors
Nikhil K. Chanani, MD
Division of Cardiology, Sibley Heart Center Cardiology, Emory University and Childrens Healthcare of Atlanta, Atlanta, GA, USA
Shannon E.G. Hamrick, MD
Divisions of Neonatology and Cardiology, Emory University and Childrens Healthcare of Atlanta, Emory Childrens Center, Atlanta, GA, USA
Consulting Editor
Lucky Jain

Clinics Review Articles

www.perinatology.theclinics.com

March 2016 Volume 43 Number 1
Table of Contents
Cover image
Title page
Copyright
Contributors
Consulting Editor
Editors
Authors
CME Accreditation Page
Forthcoming Issues
Forthcoming Issues
Recent Issues
Erratum
Foreword. The Journey to Adult Congenital Heart Disease
References
Preface. Perinatal Cardiovascular Disease
Risk Assessment and Management of the Mother with Cardiovascular Disease
Key points
Maternal mortality: impact of cardiovascular disease
Congenital heart defects: repaired, not cured
Preconception counseling for the woman with cardiovascular disease
Determining maternal cardiovascular risk
Maternal cardiovascular complications of pregnancy
Specific cardiac conditions
Labor and delivery
Impact of maternal heart disease on the developing fetus
Summary
References
Fetal Diagnostics and Fetal Intervention
Key points
Introduction
Rates of fetal diagnosis
Obstetric screening
Fetal echocardiography
Complete fetal echocardiogram
Sequential segmental approach
Assessment of fetal cardiac rhythm
Limitations of fetal echocardiography
Fetal interventions
Summary
References
Genetic and Developmental Basis of Cardiovascular Malformations
Key points
Introduction
The genetic basis of cardiovascular malformations
Gene dosage as a mechanism for cardiovascular malformation
Understanding the genetic basis of syndromic cardiovascular malformation can identify important genes for isolated cardiovascular malformation
Blurring the boundaries: single-gene defects that can cause both syndromic and isolated cardiovascular malformations
The developmental basis for cardiovascular malformations: genes and pathways required for critical stages of heart formation
Phenotypic heterogeneity and locus heterogeneity
Mutations in developmental pathways may result in latent disease
Decreased penetrance, variable expressivity, and complex inheritance: lessons from mouse models
Epigenetic factors in cardiovascular malformation
Future developments
Summary
References
Perinatal and Delivery Management of Infants with Congenital Heart Disease
Key points
Introduction
Fetal echocardiography and risk of hemodynamic instability at birth
Antenatal fetal surveillance after a diagnosis of congenital heart disease
Delivery planning for neonates prenatally diagnosed with congenital heart disease
Summary
References
Screening for Critical Congenital Heart Disease
Key points
Introduction
What is critical congenital heart disease screening?
Technique for critical congenital heart disease screening
Interpretation of screening results
Special settings
Limitations of screening
Summary
References
Recognition of Undiagnosed Neonatal Heart Disease
Key points
Introduction
Congenital heart defects
References
Fetal and Neonatal Arrhythmias
Key points
Introduction
Normal impulse generation and propagation
Methods of perinatal cardiac rhythm assessment
Mechanisms of arrhythmias
Consequences of arrhythmias
Assessment of arrhythmias
Arrhythmias presenting with an irregular rhythm
Arrhythmias presenting with a slow heart rate
Arrhythmias presenting with a fast heart rate
Summary
References
Recent Advances in the Treatment of Preterm Newborn Infants with Patent Ductus Arteriosus
Key points
Introduction
Symptoms and hemodynamic significance of patent ductus arteriosus
Current treatment options for patent ductus arteriosus of preterm newborn infants
Intravenous indomethacin and ibuprofen
Oral ibuprofen
Paracetamol (acetaminophen)
Surgical ligation and catheter intervention of hemodynamically significant patent ductus arteriosus
Summary
References
Nutrition in the Cardiac Newborns: Evidence-based Nutrition Guidelines for Cardiac Newborns
Key points
Nutritional requirements in neonates with congenital heart disease
Protein studies in sick/preterm neonates
Necrotizing enterocolitis in cardiac newborns
Necrotizing enterocolitis in preterm neonates with congenital heart disease
Standardized feeding protocols
Breast milk studies
Intestinal microbiota and probiotics
Postdischarge nutrition and growth
Need for gavage feeding at discharge
References
Developmental Care Rounds: An Interdisciplinary Approach to Support Developmentally Appropriate Care of Infants Born with Complex Congenital Heart Disease
Key points
Introduction
Components of developmental care
Interdisciplinary developmental care rounds
Barriers to implementing developmental care
Case example
Summary
References
Management of the Preterm Infant with Congenital Heart Disease
Key points
Introduction
Timing of delivery and obstetric considerations
Preoperative considerations
Outcomes: mortality and common complications of prematurity
Summary
References
Neurodevelopmental Outcomes of the Child with Congenital Heart Disease
Key points
Introduction
Genetic comorbidity
Perioperative neurologic findings
Domains of neurodevelopmental impairments
Clinical implications
Summary/discussion
References
Pulmonary Hypertension and Pulmonary Vasodilators
Key points
Introduction
Definitions and criteria for diagnosis of pulmonary hypertension
Therapies for pulmonary hypertension: acute and chronic
Summary
References
Index
Copyright
ELSEVIER
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CLINICS IN PERINATOLOGY Volume 43, Number 1
March 2016 ISSN 0095-5108, ISBN-13: 978-0-323-41657-3
Editor: Kerry Holland
Developmental Editor: Casey Jackson
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