Management of Medication-related Osteonecrosis of the Jaw, An Issue of Oral and Maxillofacial Clinics of North America 27-4
112 pages
English

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Management of Medication-related Osteonecrosis of the Jaw, An Issue of Oral and Maxillofacial Clinics of North America 27-4 , livre ebook

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112 pages
English

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Description

Editor Salvatore Ruggiero, DMD, MD and authors review the Diagnosis, Management and Prevention of Medication-related Osteonecrosis of the Jaw. Articles will include: Osteoporosis and bone modulation therapies: indications and outcomes; Antiresorptive therapies for the treatment of malignant osteolytic bone disease; Clinical presentation and staging of antiresorptive agent-induced osteonecrosis of the jaw; Epidemiology and risk factors of antiresorptive agent-induced osteonecrosis of the jaw; Basic science research of antiresorptive agent-induced osteonecrosis of the jaw: an update; Pathophysiology of antiresorptive agent-induced osteonecrosis of the jaw: what we know and what we don’t know; The genetics of osteonecrosis of the jaw; Preventive strategies for patients at risk of antiresorptive agent-induced osteonecrosis of the jaw; Non-operative and operative therapies for treatment of antiresorptive agent-induced osteonecrosis of the jaw; The role of anti-angiogenic therapy in the development of osteonecrosis of the jaw; Antiresorptive therapies: what they are and how do they work, and more!

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Publié par
Date de parution 07 janvier 2016
Nombre de lectures 0
EAN13 9780323413473
Langue English
Poids de l'ouvrage 2 Mo

Informations légales : prix de location à la page 0,5242€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

Extrait

Management of Medication-related Osteonecrosis of the Jaw
Oral and Maxillofacial Surgery Clinics of North America
Editor
Salvatore L. Ruggiero, DMD, MD, FACS
New York Center for Orthognathic and Maxillofacial Surgery, Lake Success, NY, USA
Consulting Editor
Richard H. Haug

Clinics Review Articles

www.oralmaxsurgery.theclinics.com

November 2015 Volume 27 Number 4
Table of Contents
Cover image
Title page
Copyright
Contributors
Consulting Editor
Editor
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Preface
Diagnosis and Staging of Medication-Related Osteonecrosis of the Jaw
Key points
Introduction
Nomenclature and diagnostic criteria
Clinical presentation
Imaging
Histopathology
Clinical staging
Summary
References
Pathophysiology of Osteonecrosis of the Jaws
Key points
Introduction
Proposed hypotheses of medication-related osteonecrosis of the jaw pathophysiology
Summary
References
Medication-Related Osteonecrosis of the Jaw: Basic and Translational Science Updates
Key points
Introduction
Medication-related osteonecrosis of the jaw at the cell level-bisphosphonate action on cells and tissue accumulation
Animal models of medication-related osteonecrosis of the jaw: the toolbox is full and ready to be put to work
Where do we go from here?
References
The Frequency of Medication-related Osteonecrosis of the Jaw and its Associated Risk Factors
Key points
Introduction
Summary of findings
Risk factors for medication-related osteonecrosis of the jaws
Summary
References
Management of Medication-Related Osteonecrosis of the Jaw
Key points
Introduction
Medical management
Surgical management
Summary
References
Preventive Strategies for Patients at Risk of Medication-related Osteonecrosis of the Jaw
Key points
Introduction
Patients at risk
Preventive strategies before commencement of antiresorptives
Preventive strategies after commencement of antiresorptives
Summary
References
Pharmacogenetics of Bisphosphonate-associated Osteonecrosis of the Jaw
Key points
Introduction
Pharmacogenetics and adverse drug reactions
Genome-wide association studies on osteonecrosis of the jaw
Candidate gene studies on osteonecrosis of the jaw
Summary
References
The Role of Antiangiogenic Therapy in the Development of Osteonecrosis of the Jaw
Key points
Introduction
Medication-related osteonecrosis of the jaws in patients receiving the vascular endothelial growth factor inhibitor bevacizumab, with and without antiresorptive exposure
Medication-related osteonecrosis of the jaws in patients receiving tyrosine kinase inhibitors, with and without antiresorptive exposure
Medication-related osteonecrosis of the jaws in patients receiving mammalian target of rapamycin inhibitors with or without antiresorptive medications
Medication-related osteonecrosis of the jaws and immunomodulatory agents with an antiangiogenic profile
Summary
References
Antiresorptive Therapies for Osteoporosis
Key points
References
Antiresorptive Therapies for the Treatment of Malignant Osteolytic Bone Disease
Key points
Introduction
Pamidronate
Zoledronic acid (zoledronate)
Denosumab
Summary
References
Indications and Outcomes of Osteoporosis and Bone Modulation Therapies
Key points
References
Index
Copyright
ELSEVIER
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ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA Volume 27, Number 4
November 2015 ISSN 1042-3699, ISBN-13: 978-0-323-41346-6
Editor: John Vassallo; j.vassallo@elsevier.com
Developmental Editor: Colleen Viola
2015 Elsevier Inc. All rights reserved.
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Printed in the United States of America.
Contributors
Consulting Editor
RICHARD H. HAUG, DDS , Professor and Chief, Oral Maxillofacial Surgery, Carolinas Medical Center, Charlotte, North Carolina
Editor
SALVATORE L. RUGGIERO, DMD, MD, FACS , New York Center for Orthognathic and Maxillofacial Surgery, Lake Success; Clinical Professor, Department of Oral and Maxillofacial Surgery, Stony Brook University, Stony Brook; Clinical Professor, Department of Dental Medicine, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, New York
Authors
TARA AGHALOO, DDS, MD, PhD , Professor and Assistant Dean for Clinical Research, Section of Oral and Maxillofacial Surgery, Division of Diagnostic and Surgical Sciences, UCLA School of Dentistry, Los Angeles, California
MATTHEW R. ALLEN, PhD , Associate Professor, Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana
THOMAS B. DODSON, DMD, MPH , Professor and Chair; Associate Dean for Hospital Affairs, Department of Oral and Maxillofacial Surgery, University of Washington School of Dentistry, Seattle, Washington
JOHN E. FANTASIA, DDS , Professor, Division of Oral and Maxillofacial Pathology, Department of Dental Medicine, Hofstra North Shore-LIJ School of Medicine, New Hyde Park, New York
S. FEDELE, DDS, PhD , UCL Eastman Dental Institute, University College London; Biomedical NIHR Research Centre, University College London Hospitals, London, United Kingdom
P.L. FUNG, BDS, MSc, PhD , UCL Eastman Dental Institute, University College London, London, United Kingdom
REGINALD H. GOODDAY, DDS, MSc, FRCD(C), FICD, FACD , Professor, Department of Oral and Maxillofacial Sciences, Faculty of Dentistry, Dalhousie University

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