Pediatric Infectious Disease: Part I, An Issue of Infectious Disease Clinics of North America

Mary Anne Jackson

Description

This issue of Infectious Disease Clinics of North America, Guest Edited by Mary Anne Jackson, MD and Angela Myers, MD, is Part I of a 2-part issue devoted to Pediatric Infectious Diseases. Drs. Jackson and Myers have assembled a group of expert authors to review the following topics: Diagnosis and Management of Kawasaki Disease; Neonatal HSV Infection; Use of Newer Diagnostics for Pediatric Tuberculosis; Recognition and Prompt Treatment for Tick Borne Infections; Prevention of Recurrent Staphylococcal Skin Infections; Evaluation and Management of the Febrile Young Infant; New Horizons for Pediatric Antimicrobial Stewardship; Pitfalls in Diagnosis of Pediatric Clostridium Difficile Diarrhea; The Changing Epidemiology of Pediatric Endocarditis; Neonatal Parechovirus Infection; Osteoarticular infections in Children; and Pediatric CMV Disease.

Sujets

• Médecine
• Médecine Générale
• Infectious Diseases
• Medical

Informations

• Publié par: Elsevier
• Date de parution: 07 septembre 2015
• Nombre de lectures: 1
• EAN13: 9780323395687
• Langue: English
• Poids de l'ouvrage: 1 Mo

Extrait

Clinics Review Articles Infectious Disease Clinics of North America
Pediatric Infectious Disease: Part I

Mary Anne Jackson, MD, FAAP, FIDSA
Infectious Diseases, Children’s Mercy Hospital, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA

Angela L. Myers, MD, MPH, FAAP, FPIDS
Pediatric Infectious Diseases, Children’s Mercy Hospital, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA
ISSN  0891-5520 Volume 29 • Number 3 • September 2015
Elsevier
Table of Contents
Cover image
Title page
Copyright
Contributors
Consulting Editor
Editors
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Preface
Neonatal Herpes Simplex Virus Infection
Key points
Introduction
Pathogen description
Risk factors
Seroprevalence of herpes simplex virus infection and incidence of neonatal disease
Geographic distribution of disease burden
Clinical correlation
Patient history and physical examination
Diagnostic testing
Treatment
Clinical outcomes and complications
Summary
Strain Variation and Disease Severity in Congenital Cytomegalovirus Infection
Key points
Introduction
Genetic definitions
General information—the cytomegalovirus genome and cytomegalovirus strains
What is the best source for genotypic studies?
Genetic variability in the tumor necrosis factor receptor–like gene, UL144
Genetic variability in UL146 and UL147
US28
Glycoprotein N (UL73)
Glycoprotein O (UL74)
Glycoprotein H (UL75)
Glycoprotein B (UL55)
Mixed infection with multiple cytomegalovirus strains
The era of next-generation sequencing
Summary
Human Parechovirus 3
Key points
Introduction
Virology
Tropism
Epidemiology
Clinical presentation, differential diagnosis, and empiric approach
Clinical differentiation from enterovirus
Useful routine laboratory tools
The key is cerebrospinal fluid testing
MRI changes with human parechovirus 3
Diagnosis
Management
Outcome
Prevention of Recurrent Staphylococcal Skin Infections
Key points
Introduction
The emergence of community-associated methicillin-resistant Staphylococcus aureus
Epidemiology of pediatric Staphylococcus aureus skin and soft tissue infections
Pathogenesis of Staphylococcus aureus skin and soft tissue infections
Skin and soft tissue infection characteristics and initial management
Epidemiology of recurrent skin and soft tissue infection
Prevention strategies: decolonization
A potential undesirable repercussion of decolonization: antimicrobial resistance
Future directions
Summary
Pitfalls in Diagnosis of Pediatric Clostridium difficile Infection
Key points
Changing epidemiology of C difficile infection
Available C difficile diagnostic tests and their characteristics in adults and children
Challenges to accurate diagnosis of pediatric C difficile infection
Summary
New Diagnostics for Childhood Tuberculosis
Key points
Introduction
From conceptualization to large-scale implementation
Approaches to testing
Assays for detecting infection
Assays for detecting the organism and drug resistance
Additional assays for detecting the organism
Additional assays for detecting drug resistance
Summary
New Horizons for Pediatric Antibiotic Stewardship
Key points
Introduction
Antimicrobial stewardship guidelines and strategies
Trends in emergence of pediatric antimicrobial stewardship programs
Targets for pediatric stewardship
Expansion of pediatric antimicrobial stewardship programs outside the hospital setting
The future of pediatric antimicrobial stewardship programs
Summary
The Changing Epidemiology of Pediatric Endocarditis
Key points
Introduction
Incidence
Reports on microbiology of infective endocarditis
Improvement in diagnosis
Summary
The Complexities of the Diagnosis and Management of Kawasaki Disease
Key points
Introduction
Incidence and mortality rates
Patient history
Physical examination
Other clinical manifestations of Kawasaki disease
Imaging and additional testing
Diagnosis of incomplete (atypical) Kawasaki disease
Primary therapy
Research studies on adjunctive primary therapy
Refractory Kawasaki disease
Clinical outcomes and complications
Recognition of and Prompt Treatment for Tick-Borne Infections in Children
Key points
Introduction
Etiologic agents and vectors
Epidemiology
Clinical features
Diagnosis
Antibiotic therapy
Clinical outcomes
Prevention
Summary
Osteoarticular Infections in Children
Key points
Introduction
Imaging and additional testing
Surgical treatment
Medical treatment
Summary
Evaluation and Management of Febrile, Well-appearing Young Infants
Key points
Introduction
Prevalence/incidence
Clinical correlation, patient history, and physical examination
Additional testing
Therapeutic options
Clinical outcomes
Complications and concerns
Summary/discussion
Index
Copyright
Elsevier
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INFECTIOUS DISEASE CLINICS OF NORTH AMERICA Volume 29, Number 3
September 2015 ISSN 0891–5520, ISBN-13: 978-0-323-39567-0
Editor: Kerry HollandDevelopmental Editor: Donald Mumford
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Contributors

Consulting Editor
HELEN W. BOUCHER, MD, FIDSA, FACP
Director, Infectious Diseases Fellowship Program, Division of Geographic Medicine and Infectious Disea