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Publié par | ernst-moritz-arndt-universitat_greifswald |
Publié le | 01 janvier 2009 |
Nombre de lectures | 14 |
Langue | English |
Extrait
Aus dem Institut für Epidemiologie und Sozialmedizin
der Medizinischen Fakultät der Ernst-Moritz-Arndt-Universität Greifswald
Direktor: Prof. Dr. Ulrich John
Alcohol problem drinking among general hospital inpatients:
Proportions and subtypes in a northeastern area of Germany
Inaugural - Dissertation
zur
Erlangung des akademischen Grades
Doktor der Naturwissenschaften in der Medizin
(Dr. rer. med.)
der
Medizinischen Fakultät
der
Ernst-Moritz-Arndt-Universität
Greifswald
2009
vorgelegt von: Beate Coder
geboren am: 31.05.1978
in: Zwickau
Dekan: Prof. Dr. Heyo K. Kroemer
1. Gutachter: Prof. Dr. Ulrich John (Greifswald)
2. Gutachter: Prof. Dr. Alfons Hamm (Greifswald)
3. Gutachter: Prof. Dr. Harald J. Freyberger (Greifswald)
4. Gutachter: Prof. Dr. Gerhard Bühringer (Dresden)
Ort, Raum: Greifswald, Hörsaal der Klinik und Poliklinik für
Hautkrankheiten, Fleischmannstr. 42-44
Tag der Disputation: 10. Juni 20093
SUMMARY ....................................................................................................................... 5
ZUSAMMENFASSUNG .................................................................................................. 7
1 INTRODUCTION ................................................................................................. 10
1.1 Alcohol problem drinking: Definitions .......................................................................................... 10
1.2 Alcohol-related morbidity and mortality ....................................................................................... 11
1.3 Proportions of individuals with alcohol problem drinking .......................................................... 12
1.4 Reported beverage consumed and alcohol-related diseases ......................................................... 13
1.5 Three subtypes of drinking above recommended levels ............................................................... 14
1.6 Aims ................................................................................................................................................... 16
2 METHODS ............................................................................................................. 18
2.1 Sample ............................................................................................................................................... 18
2.2 Measures ........................................................................................................................................... 20
2.3 Data analysis ..................................................................................................................................... 22
2.3.1 Study 1: Proportions of alcohol problem drinking .................................................................... 22
2.3.2 Study 2: Reported beverage consumed and alcohol-related diseases ....................................... 23
2.3.3 Study 3: Three subtypes of drinking above recommended levels ............................................. 23
3 RESULTS ............................................................................................................... 24
3.1 Study 1: Proportions of alcohol problem drinking
(Coder, Freyer-Adam, Bischof et al., 2008) ..................................................................... 24
3.2 Study 2: Reported beverage consumed and alcohol-related diseases
(Coder et al., 2009) ............................................................................................................. 25
3.3 Study 3: Three subtypes of drinking above recommended levels
(Coder, Freyer-Adam, Lau et al., 2008), (Coder, Freyer-Adam, Rumpf, John &
Hapke, submitted) ............................................................................................................ 26
3.3.1 Baseline ..................................................................................................................................... 26
3.3.2 Follow-up .................................................................................................................................. 27
4 DISCUSSION ......................................................................................................... 28
4.1 General Discussion ........................................................................................................................... 28
4.1.1 Alcohol problem drinking among general hospital inpatients .................................................. 28 4
4.1.2 Alcohol-related diseases among men who drink spirits only .................................................... 29
4.1.3 At-risk and heavy episodic drinking among men: A subclinical diagnosis? ............................. 30
4.2 Limitations ........................................................................................................................................ 31
4.2.1 Sensitivity of screening instruments ......................................................................................... 31
4.2.2 Severity of alcohol dependence ................................................................................................ 32
4.2.3 Smoking co-occurrence and somatic multimorbidity ............................................................... 32
4.2.4 The transtheoretical model of intentional behavior change as theoretical framework .............. 32
4.2.5 Generalizability ......................................................................................................................... 33
4.2.6 Power ........................................................................................................................................ 33
4.3 Practical implications ...................................................................................................................... 33
4.4 Outlook ............................................................................................................................................. 34
5 REFERENCES ...................................................................................................... 36
6 SCIENTIFIC PAPERS ......................................................................................... 43
6.1 Coder, B., Freyer-Adam, J., Bischof, G., Pockrandt, C., Hartmann, B., Rumpf, H. J.,
John, U. & Hapke, U. (2008) ........................................................................................................... 45
6.2 Coder, B., Freyer-Adam, J., Lau, K., Riedel, J., Rumpf, H. J., Meyer, C., John, U. &
Hapke, U. (2009) .............................................................................................................................. 54
6.3 Coder, B., Freyer-Adam, J., Lau, K., Bischof, G., Riedel, J., Rumpf, H. J., John, U. &
Hapke, U. (2008) ................ 61
6.4 Coder, B., Freyer-Adam, J., Rumpf, H. J., John, U. & Hapke, U. (submitted) .......................... 76
APPENDICES ................................................................................................................. 87
Appendix A – Eidesstattliche Erklärung .................................................................................................. 88
Appendix B – Curriculum Vitae ............................................................................................................... 89
Appendix C – List of scientific papers ...................................................................................................... 90
ACKNOWLEDGEMENT/ DANKSAGUNG ............................................................... 94 5
Summary
Alcohol-related somatic disorders are highly prevalent among general hospital inpatients.
Alcohol problem drinking can be differentiated into alcohol use disorders (alcohol
dependence and alcohol abuse) and three subtypes of drinking above recommended levels (at-
risk drinking only, heavy episodic drinking only, at-risk and heavy episodic drinking).
Whereas alcohol use disorders are ascertained via different diagnostic criteria, drinking above
recommended levels is defined solely by the frequency and quantity of alcohol consumption.
According to the British Medical Association, at-risk drinkers are characterized by a daily
average consumption of 30g or more of pure alcohol for men and 20g or more for women.
Heavy episodic drinkers are individuals with irregular excessive alcohol consumption. The