Resistance/Susceptibility to malaria ! Denis Deli"!# "$ %&% ' !(( !)*' ++,-*'++),.!'!*InhaltsverzeichnisInhaltsverzeichnis Vorwort I-I 1. Introduction 1-6 1.1 Malaria-key facts 1-4 1.2 Resistance/Susceptibility to Plasmodium chabaudi malaria 5-6 1.3 Project objectives 62. Results 7-102 2.1 Loss of ability to self-heal malaria upon taurine transporter deletion 7-15 2.2 Testosterone-induced upregulation of miRNAs in the female mouse liver 16-23 2.3 Testosterone-induced permanent changes of hepatic gene expression in female mice sustained during Plasmodium chabaudi malaria infection 24-36 2.4 Hepatic miRNA expression reprogrammed by Plasmodium chabaudi malaria 37-48 2.