Synthesis of conformationally restricted amino acids and their use in the preparation of biologically active peptides and peptidomimetics [Elektronische Ressource] / vorgelegt von Cattaneo Cristian
Synthesis of conformationally restricted amino acids and their use in the preparation of biologically active peptides and peptidomimetics Dissertation Zur Erlangung des Doktorgrades der Naturwissenschaften Dr. rer. nat. der Fakultät für Chemie und Pharmazie der Universität Regensburg und der Università degli studi di Mlano (Italia ) vorgelegt von Cattaneo Cristian aus Comun Nuovo (Italy) Regensburg 2008 1 UNIVERSITA’ DEGLI STUDI DI MILANO Facoltà di Farmacia Dottorato di ricerca in Chimica del Farmaco (Ciclo XXI) SYNTHESIS OF CONFORMATIONAL RESTRICTED AMINO ACIDS AND THEIR USE IN THE PREPARATION OF BIOLOGICALLY ACTIVE PEPTIDES AND PEPTIDOMIMETICS Tesi del Dottor Cristian CATTANEO Matr. Nr. R06578 CHIM 06 Relatori: Prof.ssa M. Luisa GELMI Prof. Oliver REISER Coordinatore : Prof.ssa Marina CARINI Anno Accademico 2007-2008 2 To raise new questions, new possibilities, to regard old problems from a new angle, requires creative imagination and marks real advance in science.