Occurrence, distribution and fate of pharmaceuticals and further polar contaminants in the marine environment [Elektronische Ressource] / vorgelegt von Stefan Weigel

Occurrence, distribution and fate of pharmaceuticals and further polar contaminants in the marine environment DISSERTATION zur Erlangung des Doktorgrades des Fachbereichs Chemie der Universit t Hamburg vorgelegt von Stefan Weigel aus Hamburg Hamburg 2003 The present thesis was carried out between August 1998 and October 2003 at the University of Hamburg, Institute of Organic Chemistry, in the research group of Prof. Dr. H. H hnerfuss. University of Hamburg Institute of Organic Chemistry Martin-Luther-King-Platz 6 20146 Hamburg Germany http://www.chemie.uni-hamburg.de/oc/hfuss/ 1. Reviewer: Prof. Dr. H. H hnerfuss 2. Reviewer: Dr. h.c. W. Francke Examen rigorosum: 12 December 2003Table of contents 1 INTRODUCTION............................................................................................................ 1 1.1 Contamination of the marine environment.......................................................... 1 1.2 Pharmaceuticals and personal care products (PPCPs) in the environment..... 4 1.2.1 Background...................................................................................................... 4 1.2.2 Relevance........................................................................................................ 7 1.2.3 Metabolism......................................................................................