Massachusetts General Hospital Psychopharmacology and Neurotherapeutics E-Book

Jerrold F. Rosenbaum, Timothy E. Wilens, Maurizio Fava, Theodore A. Stern

Description

Put today's best approaches to work for your patients with this practical guide to cutting-edge psychopharmacologic and somatic treatments for psychiatric and neurologic conditions. Comprised of key chapters from the second edition of Stern et al.’s Massachusetts General Hospital Comprehensive Clinical Psychiatry, this user-friendly resource focuses on current psychotropic treatments, electroconvulsive therapy, and neurotherapeutics, making it an ideal quick reference for psychiatrists, psychologists, internists, and nurse practitioners.

• Stay current with hot topics in the field, including the use of antiepileptic drugs in psychiatry, ADHD medications, and often-overlooked areas such as treatment of pain.
• Benefit from the authoritative content of the parent text, MGH Comprehensive Clinical Psychiatry, 2nd Edition, now featuring new art, new tables, and key points, and updated to DSM-5 where relevant.
• Get detailed coverage of antidepressants, antipsychotics, and antianxiety medications, as well as drug interactions, side effects, and treatment adherence.
• Quickly find the information you need with a user-friendly, highly templated format that features abundant boxed summaries, bulleted points, case histories, algorithms, references, and suggested readings.
• Test your knowledge of psychopharmacology and neurotherapeutics with interactive, downloadable multiple-choice questions with detailed answers for each chapter.

Sujets

• Medical
• Médecine
• Psychiatry

Informations

• Publié par: Elsevier
• Date de parution: 27 avril 2015
• Nombre de lectures: 0
• EAN13: 9780323413237
• Langue: English
• Poids de l'ouvrage: 4 Mo

Extrait

Massachusetts General Hospital Psychopharmacology and Neurotherapeutics
First Edition
Created with content from:
Massachusetts General Hospital Comprehensive Clinical Psychiatry, Second Edition
ISBN: 978-0-323-29507-9
Editors
THEODORE A. STERN MD
Chief, Avery D. Weisman Psychiatry Consultation Service
Massachusetts General Hospital
Director, Office for Clinical Careers Massachusetts General Hospital
Ned H. Cassem Professor of Psychiatry in the field of Psychosomatic Medicine/Consultation
Harvard Medical School
Boston, MA, USA
MAURIZIO FAVA MD
Director, Clinical Research Program
Executive Vice-Chair, Department of Psychiatry
Executive Director, Clinical Trials Network and Institute, Massachusetts General Hospital
Slater Family Professor of Psychiatry, Harvard Medical School
Boston, MA, USA
TIMOTHY E. WILENS MD
Senior Staff, Child Psychiatry and Pediatric Psychopharmacology
Director of the Center for Addiction Medicine
Massachusetts General Hospital
Associate Professor of Psychiatry
Harvard Medical School
Boston, MA, USA
JERROLD F. ROSENBAUM MD
Psychiatrist-in-Chief, Massachusetts General Hospital
Chair, Executive Committee on Research
Massachusetts General Hospital
Stanley Cobb Professor of Psychiatry
Harvard Medical School
Boston, MA, USA

London, New York, Oxford, Philadelphia, St Louis, Sydney, Toronto
Table of Contents
Cover image
Title page
Copyright
Preface
List of Contributors
1 Psychiatric Neuroscience: Incorporating Pathophysiology into Clinical Case Formulation
Overview
History of Psychiatric Neuroscience
Psychiatric Diagnosis: Biomarkers and Biological Validity
Methods in Psychiatric Neuroscience
Biological Case Formulation: Neuroscientific Content and Process
Overview of the Structure of the Central Nervous System
Cellular Diversity in the Brain: Neurons and Glia
The Structure of the Synapse
A Review of Clinically Relevant Neurotransmitter Systems
Genes, Environment, and Epigenetics
Conclusion
Acknowledgments
References
Multiple Choice Questions
Multiple Choice Answers
2 Treatment Adherence
Overview
Epidemiology of Adherence
Clinical and Economic Impact of Non-Adherence
Risk Factors for Non-Adherence
Assessing Adherence
Integrating Adherence Into the Treatment Course
Problem-Solving Barriers to Adherence
Future Directions
Conclusion
References
Multiple Choice Questions
Multiple Choice Answers
3 Antidepressants
Overview
Mechanism of Action
Clinical Uses of Antidepressants
Choice of an Antidepressant
References
Multiple Choice Questions
Multiple Choice Answers
4 Pharmacological Approaches to Treatment-Resistant Depression
Overview
Definition of Treatment-Resistant Depression
Staging Models of Treatment-Resistant Depression
Clinical Features Associated with Treatment-Resistant Depression
Clinical Approach to Treatment-Resistant Depression
Common Treatment Strategies for Treatment-Resistant Depression
Research Challenges
Conclusions
References
Multiple Choice Questions
Multiple Choice Answers
5 Bipolar Disorder
Overview
Epidemiology and Risk Factors
Historical Context
Clinical Features and Phenomenology
Associated Illness Features
Features of Longitudinal Course
Neurobiology and Pathophysiology
Evaluation, Tests, and Laboratory Work-Up
Consequences of Misdiagnosis
Role of Diagnostic Testing (Including Neuroimaging and Other Biomarkers)
Tools for Screening, Diagnosis, and Symptom Monitoring
Treatment
Special Considerations in Treatment
Prognosis
Medical Co-Morbidity among Bipolar Patients
Controversies
References
Multiple Choice Questions
Multiple Choice Answers
6 The Pharmacotherapy of Anxiety Disorders
Overview
Panic Disorder and Agoraphobia
Generalized Anxiety Disorder
Social Anxiety Disorder
Conclusions and Future Directions
References
Multiple Choice Questions
Multiple Choice Answers
7 Antipsychotic Drugs
Introduction
History
Currently Available Antipsychotic Agents
General Clinical Considerations
Drug Selection
First-Generation ( Typical ) Antipsychotics
Extrapyramidal Symptoms and Tardive Dyskinesia
Neuroleptic Malignant Syndrome
Second-Generation ( Atypical ) Antipsychotics
Drug Interactions with Antipsychotic Agents
Ongoing Challenges
References
Multiple Choice Questions
Multiple Choice Answers
8 Lithium and Its Role in Psychiatry
Historical Context
Lithium's Mechanism of Action
Pharmacokinetics and Pharmacodynamics
Evidence for Lithium's Efficacy
Principles of Lithium Treatment
Current Controversies and Future Directions
References
Multiple Choice Questions
Multiple Choice Answers
9 The Use of Antiepileptic Drugs in Psychiatry
Overview: Historical Context
Pharmacokinetics, Pharmacodynamics, Adverse Effects, and Monitoring
Other Anticonvulsants
Conclusion
References
Multiple Choice Questions
Multiple Choice Answers
10 Stimulants and Other Medications for ADHD
Overview
Stimulants
Atomoxetine
Suggested Management Strategies Across the Life span
Safety of Medications Used to Treat Attention-Deficit/Hyperactivity Disorder
Alternative (Not FDA-Approved) Treatments for Attention-Deficit/Hyperactivity Disorder
Novel Treatments for Attention-Deficit/Hyperactivity Disorder
Pharmacotherapy of Attention-Deficit/Hyperactivity Disorder and Common Co-Morbid Psychiatric Disorders
Managing Sub-Optimal Responses
Conclusion
References
Multiple Choice Questions
Multiple Choice Answers
11 Drug-Drug Interactions in Psychopharmacology
Overview
Classification
Pharmacokinetics
Antipsychotics
Mood Stabilizers
Antidepressants
Benzodiazepines
Psychostimulants and Modafinil
References
Multiple Choice Questions
Multiple Choice Answers
12 Side Effects of Psychotropic Medications
Overview
Antidepressants
Mood Stabilizers
Antipsychotics
Antianxiety and Sleep Agents
Other Agents Used in the Treatment of Psychiatric Conditions
References
Multiple Choice Questions
Select the appropriate answer
13 Natural Medications in Psychiatry
Overview
Efficacy and Safety
Mood Disorders
Anxiety and Insomnia
Premenstrual and Menopausal Symptoms
Cognition and Dementia
Conclusion
References
Multiple Choice Questions
Multiple Choice Answers
14 Dementia
Overview
Epidemiology of Dementia
The Role of Age of Onset
Evaluation of the Patient with Suspected Dementia
Alzheimer's Disease
Dementia with Lewy Bodies
Frontotemporal Dementias
Vascular Dementia
Corticobasal Degeneration
Progressive Supranuclear Palsy
Normal Pressure Hydrocephalus
Creutzfeldt-Jakob Disease
Conclusions
References
Suggested Reading
Multiple Choice Questions
Multiple Choice Answers
15 Alcohol-Related Disorders
Overview
Description and Definition
Alcohol-Induced Disorders
Alcohol Use Disorders
Etiology AND Epidemiology
Alcohol Use Disorders and Co-occurring Psychiatric Illness
Pathophysiology and Imaging
Screening and Assessment
Treatment for Alcohol Use Disorders
Conclusions
References
Multiple Choice Questions
Multiple Choice Answers
16 Drug Addiction
Overview
The Neurobiology of Addiction
Cocaine
Amphetamines
Club Drugs
Opioids
Benzodiazepines
Sedative-Hypnotics
Mixed-Drug Addiction
References
Suggested Reading
Multiple Choice Questions
Multiple Choice Answers
17 Pathophysiology, Psychiatric Co-morbidity, and Treatment of Pain
Overview
Epidemiology
Pathophysiology of Pain Transmission
Cortical Substrates for Pain and Affect
Interactions between Pain and Psychopathology
Pain Terminology
Assessment of Pain
Core Psychopathology and Pain-Related Psychological Symptoms
Pain and Co-Morbid Psychiatric Conditions
General Principals of Multimodal Analgesia
Treatment of Pain Behavior and the Use of Multidisciplinary Pain Clinics
Rehabilitation
Conclusions
References
Multiple Choice Questions
Multiple Choice Answers
18 Neurotherapeutics
Overview
Ablative Limbic System Surgery
Deep Brain Stimulation
Vagus Nerve Stimulation
Electroconvulsive Therapy
Transcranial Magnetic Stimulation
Conclusion
References
Multiple Choice Questions
Multiple Choice Answers
19 Electroconvulsive Therapy
Overview
Indications for Electroconvulsive Therapy
Risk Factors Associated with Electroconvulsive Therapy
Technique for Conducting Electroconvulsive Therapy
Adverse Effects of Electroconvulsive Therapy
Maintenance E