Cet ouvrage fait partie de la bibliothèque YouScribe
Obtenez un accès à la bibliothèque pour le lire en ligne
En savoir plus

Mercury resistance (mer) operons in enterobacteria abstract

4 pages
Publié par :
Ajouté le : 21 juillet 2011
Lecture(s) : 1 091
Signaler un abus

Vous aimerez aussi

Biometals 2002: Third International Biometals Symposium
Mercury resistance (mer) operons in enterobacteria 1 J. L. Hobman , A. M. M. Essa and N. L. Brown School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.
Abstract GVhTkho hVi]ijRdTV ]i WekdU ]d cRdo ZVdVhR eW SRTjVh]R. 7ecced RcedZij VdjVheSRTjVh]R RhV jhRdifeiedi hVbRjVU je Ld10’ m[]T[ ]i Sej[ cVh( Tkh]T ]ed( RdU ijhVfjecoT]d(}ifVTj]decoT]d( RdU ikbf[edRc]UV(hVi]ijRdj. Ij[Vh Ld10(hVbRjVU jhRdifeiedi eWjVd [RlV U]ffVhVdj Rdj]S]ej]T hV( i]ijRdTVi TecfRhVU m]j[ Ld10’ Skj i[RhV cRdo ded(Rdj]S]ej]T(hVi]ijRdTV ZVdVi m]j[ ]j. Cd j[]i Rhj]TbV mV U]iTkii feii]SbV cVT[Rd]ici Weh j[V Vlebkj]ed eW Ld10RdU hVbRjVU ZVdVj]T VbVcVdji.
Introduction GVhTkho RdU cVhTkho(TedjR]d]dZ TecfekdUi’ ikT[ Ri cVhTkh]T T[beh]UV %BZ7b)’ cVhTkheki # T[beh]UV %BZ 7b ) RdU cVhTkh]T ikbf[]UV %BZK)’ # # [RlV SVVd kiVU Ri cVU]T]dVi Weh j[V jhVRjcVdj eW cRdo [kcRd R]bcVdji’ hRdZ]dZ Whec Tedij]fRj]ed je ik]d U]iVRiV’ Weh cRdo [kdUhVUi eW oVRhi [,]. GVhTkho mRi fVh[Rfi ceij WRcekibo %j[ekZ[ dej dVTViiRh]bo VffiTRT]ekibo) kiVU Weh j[V jhVRjcVdj eW iof[]b]i fh]eh je j[V iodj[Vi]i RdU kiV eW j[V phij iVbVTj]lV(jen]T]jo T[Vcej[VhRfVkj]T RZVdj’ Rhi( f[VdRc]dV %PKRblRhiRd ')’m[]T[ mRi U]iTelVhVU So PRkb 9[hb]T[ RdU KR[RT[]he BRjR ]d ,9)3. L[V fheUkTj]ed eW fVd]T]bb]d ]d bRhZV gkRdj]j]Vi Ukh]dZ j[V ,90)i RdU ]ji []Z[bo VffVTj]lV jhVRj( cVdj eW iof[]b]i ikfVhTVUVU Sej[ cVhTkh]Rbi RdU PKRblRhiRd .'BemVlVh’ cVhTkho(TedjR]d]dZ TecfekdUi ikT[ Ri cVhTkh]T T[beh]UV’ cVj[ob( cVhTkho’ f[VdobcVhTkho’ cVhShec]d RdU j[]( cVheiRb mVhV ij]bb ]d m]UVifhVRU kiV ]d [eif]jRbi kdj]b Rj bVRij j[V VRhbo ,93)i ]d j[V M.E.’ M.K.5.’ AVhcRdo RdU DRfRd [-]’ RdU bRjVh ]d ej[Vh Tekd( jh]Vi. CdUVVU’ cVhTkh]Rbi RhV ij]bb ]d kiV jeURo Ri fhViVhlRj]lVi ]d lRTT]dVi RdU iecV [VRbj[TRhV fheUkTji RdU ]d UVdjRb RcRbZRci.
r Mercury resistance (Hg ) in bacteria, and Tn21 r BZ ]iWekdU ]d cRdo ZVdVhR eW SRTjVh]R’ RdU [Ri SVVd WekdU ]d Vdl]hedcVdjRb’ TeccVdiRb RdU
Key words: composite transposon, pre-antibiotic era, Tn21. r Abbreviations used: Hg , mercury resistance; ORF, open reading frame. 1 To whom correspondence should be addressed (e-mail J.L.Hobman!bham.ac.uk).
719
Tb]d]TRbbo ]cfehjRdj ]iebRjVi %hVl]VmVU ]d [..)] L[V r phij hVfehj eW BZ]d SRTjVh]R mRi RcedZDiEeTyld( IdIIuh EugPuh]d ,92)’ m[Vd GeehV [0] WekdU j[Rj cVhTkh]T iRbji kiVU je U]i]dWVTj TRjZkj kiVU ]d ikjkhVi mekbU dej ]d[]S]j Zhemj[ eWD.EugPuh ]iebRjVU Whec ikhZ]TRb mekdUi’ Skj mekbU ]d[]S]j j[V Zhemj[ eWD.EugPuhWhec ej[Vh iekhTVi. L[V r Te(jhRdiUkTj]ed eW Sej[ BZRdU fVd]T]bb]d hV( i]ijRdTV je iVdi]j]lVD.EugPuhmRi hVfehjVU 0 oVRhi r bRjVh [1]. BZmRi phij UVjVTjVU RcedZij Rdj]S]ej]T( hVi]ijRdj Tb]d]TRb VdjVheSRTjVh]R ]d ,923 [2]. KkS( iVgkVdj hViVRhT[ So ej[Vh Zhekfi %hVl]VmVU ]d [.’3)] i[emVU j[Rj j[V ZVdVj]T b]dkRZV SVjmVVd Rdj]S]ej]T hVi]ijRdTV RdU cVhTkho hVi]ijRdTV ]d VdjVheSRTjVh]R [RU eTTkhhVU fh]eh je j[V bRjV ,91)i ]d DRfRd. 5 Tb]d]TRb ijhR]d eWDTiSPlE ¯PlcPgieh]Z]dRbbo ]iebRjVU Rj j[]i j]cV ed j[V SRi]i eW ]ji ckbj]fbV Rdj]S]ej]T(hVi]ijRdTV f[VdejofV’ mRi ikS( iVgkVdjbo i[emd je TedjR]d R ckbj](hVi]ijRdTV fbRic]U’ HJ, %J,)).) J,)) TRhh]Vi’ RcedZij ej[Vh ZVdVj]T VbVcVdji’ jhRdifeied Ld10%hV( l]VmVU ]d [3)]. Ld10SVbedZi je j[V Ld2ikSZhekf eW j[V 7bRii CC jhRdifeiRSbV VbVcVdji. Cj ]i SekdUVU So .4 Sf]dlVhjVU hVfVRj 8H5 iVgkVdTVi’ RdU Vd( TeUVi R cVhTkho(hVi]ijRdTV %bPg) efVhed %bPg( CTP6A7A)’ jhRdifei]j]ed WkdTj]edi %gPhiceC RdUiceA)’ jme ej[Vh efVd hVRU]dZ WhRcVi %IJ;i)’ ugR1RdUiceM’ RdU hVi]ijRdTVi je ijhVfjecoT]d} ifVTj]decoT]d RdU ikbf[edRc]UVi [2]. L[ViV hV( i]ijRdTVi RdU ej[Vh IJ;i RhV TRhh]VU ed Rd ,,.) kS ]djVZhed’ R 8H5 VbVcVdj m]j[ j[V TRfRT]jo je RTgk]hV Rdj]S]ej]T(hVi]ijRdTV TRiiVjjVi %;]ZkhV ,; hVl]VmVU ]d [.’3]). Ld10RdU hVbRjVU VbVcVdji RhV []Z[bo ikT( TViiWkb RdU RhV fRdUVc]T. L[Vo RhV WekdU ]d Tb]d]TRb’ Vdl]hedcVdjRb RdU TeccVdiRb SRTjVh]R %hVl]VmVU ]d [3’4.)] L[]i kS]gk]jo RdU lRh]Vjo eW Ld10(hVbRjVU VbVcVdji [Ri ]d fRhj SVVd Rjjh]Sk( jVU So Ah]dijVU Vj Rb. [4] je j[V RTgk]i]j]ed eW j[V ]djVZhRiV ioijVc So Rd RdTVijeh eW Ld10VdRSb]dZ j[V hRf]U UVlVbefcVdj eW dVm jofVi eW jhRdifeied So ZVdV RTgk]i]j]ed. L[V ceij eSl]( eki RUlRdjRZV TedWVhhVU je Ld10RdU hVbRjVU jhRdifeiedi So j[V fhViVdTV eW j[V ]djVZhed ]i j[V RS]b]jo je RTgk]hV ckbj]fbV Rdj]S]ej]T hV( i]ijRdTVi. L[]i TRfRS]b]jo’ fRhj]TkbRhbo ]d cVU]( TRbbo ]cfehjRdj SRTjVh]R’ mekbU [RlV SVVd R
#2002 Biochemical Society
Un pour Un
Permettre à tous d'accéder à la lecture
Pour chaque accès à la bibliothèque, YouScribe donne un accès à une personne dans le besoin