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Adaptive control of eye movement accuracy by the cerebellum [Elektronische Ressource] : the site of plasticity and functional mechanisms / vorgelegt von Mario Prsa

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65 pages
Adaptive control of eye movement accuracy by the cerebellum: the site of plasticity and functional mechanisms Dissertation zur Erlangung des Grades eines Doktors der Naturwissenschaften der Fakultät für Biologie und der Medizinischen Fakultät der Eberhard-Karls-Universität Tübingen vorgelegt von Mario Prsa aus Montreal, Canada November - 2010 2 Dekan der Fakultät für Biologie: Prof. Dr. H. A. Mallot Dekan der Medizinischen Fakultät: Prof. Dr. I. B. Autenrieth 1. Berichterstatter: Prof. Dr. Peter Thier 2. Berichterstatter: PD Dr. Cornelius Schwarz Prüfungskommission: Prof. Dr. Peter Thier Prof. Dr. Hanspeter Mallot PD Dr. Cornelius Schwarz PD Dr. Marc Ernst Prof. Dr. Hansjörg Scherberger Defense date: Monday, October 25th, 2010 3 “I declare that I have produced the work entitled: “Adaptive control of eye saccade accuracy by the cerebellum: the site of plasticity and functional mechanisms” submitted for the award of a doctorate, on my own (without external help), have used only the sources and aids indicated and have marked passages included from other works, whether verbatim or in content, as such. I swear upon oath that these statements are true and I have not concealed anything.
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Adaptive control of eye movement accuracy by the cerebellum: the site of plasticity and functional mechanisms      Dissertation  zur Erlangung des Grades eines Doktors der Naturwissenschaften   der Fakultät für Biologie und der Medizinischen Fakultät der Eberhard-Karls-Universität Tübingen    vorgelegt von  Mario Prsa aus Montreal, Canada   November - 2010
 
                                                  
 
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                 Dekan der Fakultät für Biologie: Dekan der Medizinischen Fakultät:  1. Berichterstatter: 2. Berichterstatter:  Prüfungskommission:     
   Defense date:          
 
 
  
  
 
  
  
 
Prof. Dr. H. A. Mallot Prof. Dr. I. B. Autenrieth
Prof. Dr. Peter Thier PD Dr. Cornelius Schwarz
Prof. Dr. Peter Thier Prof. Dr. Hanspeter Mallot PD Dr. Cornelius Schwarz PD Dr. Marc Ernst Prof. Dr. Hansjörg Scherberger
Monday, October 25th, 2010
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“I declare that I have produced the work entitled: “Adaptive control of eye saccade accuracy by the cerebellum: the site of plasticity and functional mechanisms” submitted for the award of a doctorate, on my own (without external help), have used only the sources and aids indicated and have marked passages included from other works, whether verbatim or in content, as such. I swear upon oath that these statements are true and I have not concealed anything. I am aware that making a false declaration under oath is punishable by a term of imprisonment of up to three year or by a fine. I also declare that this version of the work does not differ in form or contents from the one submitted to the evaluation committee for review purposes.”   Mario Prsa Tübingen, 2010                              
 
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Preface   At the 1936 Olympic Games in Berlin, the Slovenian gymnast Leon Štukelj won his sixth and final Olympic medal. In 1998, at one hundred years of age, he was known as the oldest living Olympic gold medalist and famous for his impressive abilities to replicate in front of journalists some of the same gymnastic stances that he used to do more than 60 years ago. The physical capability of this legendary Olympian highlights the important faculty of our brains to adapt to our ever-changing physiology. Growing evidence suggests that the cerebellum mediates such adaptive processes. The work presented in this thesis uses the simple model of eye movement control in behaving macaque monkeys to reveal important aspects of cerebellum-dependent adaptation of motor function.                      Berlin, 1936:38 years old                               1998:100 years old  
      
 
                          
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