Mercury resistance (mer) operons in enterobacteria abstract

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• Publié par: julien23
• Nombre de lectures: 725
• Langue: Français

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Biometals 2002: Third International Biometals Symposium

Mercury resistance (mer) operons in enterobacteria 1 J. L. Hobman , A. M. M. Essa and N. L. Brown School of Biosciences, The University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.

Abstract GVhTkho hVi]ijRdTV ]i WekdU ]d cRdo ZVdVhR eW SRTjVh]R. 7ecced RcedZij VdjVheSRTjVh]R RhV jhRdifeiedi hVbRjVU je Ld10’ m[]T[ ]i Sej[ cVh( Tkh]T ]ed( RdU ijhVfjecoT]d(}ifVTj]decoT]d( RdU ikbf[edRc]UV(hVi]ijRdj. Ij[Vh Ld10(hVbRjVU jhRdifeiedi eWjVd [RlV U]ffVhVdj Rdj]S]ej]T hV( i]ijRdTVi TecfRhVU m]j[ Ld10’ Skj i[RhV cRdo ded(Rdj]S]ej]T(hVi]ijRdTV ZVdVi m]j[ ]j. Cd j[]i Rhj]TbV mV U]iTkii feii]SbV cVT[Rd]ici Weh j[V Vlebkj]ed eW Ld10RdU hVbRjVU ZVdVj]T VbVcVdji.

Introduction GVhTkho RdU cVhTkho(TedjR]d]dZ TecfekdUi’ ikT[ Ri cVhTkh]T T[beh]UV %BZ7b)’ cVhTkheki # T[beh]UV %BZ 7b ) RdU cVhTkh]T ikbf[]UV %BZK)’ # # [RlV SVVd kiVU Ri cVU]T]dVi Weh j[V jhVRjcVdj eW cRdo [kcRd R]bcVdji’ hRdZ]dZ Whec Tedij]fRj]ed je ik]d U]iVRiV’ Weh cRdo [kdUhVUi eW oVRhi [,]. GVhTkho mRi fVh[Rfi ceij WRcekibo %j[ekZ[ dej dVTViiRh]bo VffiTRT]ekibo) kiVU Weh j[V jhVRjcVdj eW iof[]b]i fh]eh je j[V iodj[Vi]i RdU kiV eW j[V phij iVbVTj]lV(jen]T]jo T[Vcej[VhRfVkj]T RZVdj’ Rhi( f[VdRc]dV %PKRblRhiRd ')’m[]T[ mRi U]iTelVhVU So PRkb 9[hb]T[ RdU KR[RT[]he BRjR ]d ,9)3. L[V fheUkTj]ed eW fVd]T]bb]d ]d bRhZV gkRdj]j]Vi Ukh]dZ j[V ,90)i RdU ]ji []Z[bo VffVTj]lV jhVRj( cVdj eW iof[]b]i ikfVhTVUVU Sej[ cVhTkh]Rbi RdU PKRblRhiRd .'BemVlVh’ cVhTkho(TedjR]d]dZ TecfekdUi ikT[ Ri cVhTkh]T T[beh]UV’ cVj[ob( cVhTkho’ f[VdobcVhTkho’ cVhShec]d RdU j[]( cVheiRb mVhV ij]bb ]d m]UVifhVRU kiV ]d [eif]jRbi kdj]b Rj bVRij j[V VRhbo ,93)i ]d j[V M.E.’ M.K.5.’ AVhcRdo RdU DRfRd [-]’ RdU bRjVh ]d ej[Vh Tekd( jh]Vi. CdUVVU’ cVhTkh]Rbi RhV ij]bb ]d kiV jeURo Ri fhViVhlRj]lVi ]d lRTT]dVi RdU iecV [VRbj[TRhV fheUkTji RdU ]d UVdjRb RcRbZRci.

r Mercury resistance (Hg ) in bacteria, and Tn21 r BZ ]iWekdU ]d cRdo ZVdVhR eW SRTjVh]R’ RdU [Ri SVVd WekdU ]d Vdl]hedcVdjRb’ TeccVdiRb RdU

Key words: composite transposon, pre-antibiotic era, Tn21. r Abbreviations used: Hg , mercury resistance; ORF, open reading frame. 1 To whom correspondence should be addressed (e-mail J.L.Hobman!bham.ac.uk).

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#2002 Biochemical Society