Estimating the contribution ofsequence context to nucleotidesubstitution rate heterogeneity Helen Lindsay and Gavin A Huttley

Helen Lindsay

Description

Estimating the contribution ofsequence context to nucleotidesubstitution rate heterogeneity Helen Lindsay and Gavin A. Huttley

• model• yang


• nucleotidesubstitution rate heterogeneity


• gamma rate


• allow clustering


• gamma model


• contribution ofsequence


• multiple ratedistributions

Sujets

• Lindsay

Informations

• Publié par: pefav
• Nombre de lectures: 20
• Langue: English
• Poids de l'ouvrage: 1 Mo

Extrait

Estimating the contribution of

sequence context to nucleotide

substitution rate heterogeneity

Helen Lindsay and Gavin A. Huttley

The Gamma Model

• Yang (1993) used a gamma distribution

to model rate variation in

α

- and

β

-

globin genes

• The gamma distribution is often

approximated by four equi-probable

bins