66ème congrès du comité sur les problèmes de pharmacodépendance

Afssaps

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Drugs - Chemical submission: study of case report
23/06/2004

Sujets

• DRUGS

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• Publié par: ansm-drugs
• Publié le: 23 juin 2004
• Nombre de lectures: 5
• Licence : En savoir +
  Paternité, pas d'utilisation commerciale, pas de modification
• Langue: English

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Poster 100x120 4/06/04 14:36 Page 1
CPDD Sixty-sixth Annual Scientific Meeting
Chemical submission:
study of case reports
1 2 3 3 4 4S Djezzar , F Questel , H Gourlain , D Fompeydie , N Richard , C Gatignol ,
1 1 2S Dally - CEIP Paris, Forensic medicine unit, hôpital Hôtel-Dieu,
3 4laboratory of Toxicology, hôpital F. Widal, Afssaps, Paris, France
Introduction Method
Beside the recreational context, psychoactive substances are sometimes used We propose an evaluation of clinical reports, from 2001 and 2002, registered
for criminal purposes, involving ingestion of these substances by victimes by the Center of Evaluation and Information on Pharmacodependence (CEIP)
without their knowledge. in Paris, among which 91% resulted in complaints to the police.
Chemical submission is a criminal (rape, pedophilia acts, robbery, acts of
violence) use of psychoactive substances (PAS) without victims' knowledge.
Results
VICTIMS (N: 53)
WOMEN: 33 PAS in regular treatment: MEN: 20
9 cases (BZD, IRSA, NLP, opioids…)
mean: 29.7 year-old (17-58) mean: 34.1 year-old (12-57)
1 Man: 22 (67%) AGGRESSORS 1 Man: 9 (45%)< >
2 Men: 7 2 Men: 6
Known: 32%
unrecognized: 4 1 Woman: 4
Sexual aggression: 24 (73%) ACTS OF AGRESSION > Robbery: 14 (70%)<
Physical aggression: 2 Sexual aggression: 6
Robbery (2), Unknown (5) SYMPTOMS
Amnesia: 24 cases (45%)
Disorders of vigilance: 15 cases (28%)
TOXICOLOGICAL ANALYSIS
SUBSTANCE GROUPS MAIN SUBSTANCES
40
Benzodiazepines Anti-H1 / sedatives
35 37
- diphenhydramine (2)- bromazepam (8)
30 - oxazepam (7) - doxylamine (2)
- lorazepam (5) - cyamemazine (2)
25
- tetrazepam (4) - metabolite of buclizine / hydroxyzine (2)
- methaqualone (1)20 - flunitrazepam (2)23
20
15
10 Others
10 9
5 GHB: 2 cases (of which 1 detected in drink and hairs of the victim)7
6
Harmine (Ayahuasca): 1 case
0 Other substances:
cocaine (6), lidocaine (5), MDMA (5), MDA (3), amphetamine, methamphetamine,
ephedrine, LSD, chloroquine, THC... (as ecstasy contents )
Conclusion
The detected substances are mainly those consumed for a recreational use.
Sodium gamma-hydroxybutyrate, classically known to be (the “rape drug”) CEIP
used for submission purposes, is only found in 2 cases. This result is probably
related to the very short elimination half-life of this substance. Centre d'Evaluation et d'Information sur la Pharmacodépendance
E-mail : [e-mail]
Benzodiazepines
Psychostimulants
Hallucinogens
Anti-H1 / sedatives
Anaesthetics
Antidepressive
Miscellaneous
Number of samples