Genitourinary Pathology, An Issue of Surgical Pathology Clinics

Michelle S. Hirsch

Description

This issue of Surgical Pathology Clinics focuses on diseases of the genitourinary tract: Prostate, Kidney, Bladder, Testes, and Adrenals. As with all information in this series, presentations relate to the daily practice of surgical pathologists. A practical and innovative feature in this issue is the inclusion of several articles from the “clinician’s perspective in which an oncologist discusses the diagnosis of the disease and relates this to the information they require from the pathologist. Topics include: Morphologic updates in prostate pathology; Molecular updates in prostate pathology; Diagnosis of prostate carcinoma: A clinician’s perspective; Commonly encountered renal neoplasms; Emerging dntities in renal neoplasia; Diagnosis of renal cell carcinoma: A clinician’s perspective; Morphologic and molecular characteristics of bladder cancer; Diagnosis of bladder carcinoma: A clinician’s perspective; Overview of testicular neoplasia; Diagnosis of testicular cancer: A clinician’s perspective; Overview of adrenal neoplasia; Diagnosis of adrenal carcinoma: A clinician’s perspective; Benign lesions of the GU tract . Michelle Hirsch leads this issue with a group of expert genitourinary pathologists and oncologists.

Sujets

• Medical
• Médecine
• Surgery

Informations

• Publié par: Elsevier
• Date de parution: 19 janvier 2016
• Nombre de lectures: 0
• EAN13: 9780323395885
• Langue: English
• Poids de l'ouvrage: 8 Mo

Extrait

Genitourinary Pathology
Surgical Pathology Clinics
Editor
Michelle S. Hirsch, MD, PhD
Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA
Consulting Editor
John R. Goldblum

Clinics Review Articles

www.surgpath.theclinics.com

December 2015 Volume 8 Number 4
Table of Contents
Cover image
Title page
Copyright
Contributors
Consulting Editor
Editor
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Preface
Morphologic Updates in Prostate Pathology
Abstract
Overview: update on the Gleason grading system
Update on variants of prostatic adenocarcinoma
References
Molecular Updates in Prostate Cancer
Abstract
Overview
Carcinogenesis and genetic susceptibility
Epigenetic alterations
Genetic somatic molecular alterations
Genomic signatures
Emerging clinical genomic molecular classifier assays
Emerging early detection markers and targets of therapy
References
Active Surveillance: Pathologic and Clinical Variables Associated with Outcome
Abstract
Overview
Active surveillance outcomes
Pathologic and clinical variables associated with outcome
Novel biomarkers and imaging techniques predicting aggressiveness of low-risk prostate cancer
Summary
References
Adult Renal Cell Carcinoma: A Review of Established Entities from Morphology to Molecular Genetics
Abstract
Overview
Clear cell (conventional) renal cell carcinoma
Papillary renal cell carcinoma
Chromophobe renal cell carcinoma
Xp11.2 (TFE3) translocation renal cell carcinoma
Mucinous tubular and spindle cell carcinoma
Collecting duct carcinoma
Acknowledgments
References
Emerging Entities in Renal Neoplasia
Abstract
Tubulocystic carcinoma
Clear-cell-papillary renal cell carcinoma/renal angiomyodenomatous tumor category of tumors
Thyroid-like follicular carcinoma of the kidney
Anaplastic lymphoma kinase-associated renal cell carcinoma
Renal cell carcinoma with t(6;11) translocation
Acquired cystic disease-associated renal cell carcinoma
Succinate dehydrogenase-deficient renal cell carcinoma
Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma
References
Diagnosis of Renal Cell Carcinoma: A Clinician s Perspective
Abstract
Overview
Renal mass biopsy: expectations from the clinicians
Nephrectomy specimen: expectations from the clinicians
Evolving field of prognosis and predictive biomarkers in renal cell carcinoma
Summary
References
Morphologic and Molecular Characteristics of Bladder Cancer
Abstract
Overview
Gross features
Microscopic features
Differential diagnosis
Molecular pathology of urothelial carcinoma
References
Diagnosis of Bladder Carcinoma: A Clinician s Perspective
Abstract
Overview
Non-muscle-invasive bladder cancer
Identification of bladder cancer variants
Nonmetastatic muscle-invasive bladder cancer
Summary
References
Tumors of the Testis: Morphologic Features and Molecular Alterations
Abstract
Overview
Germ cell tumors and the differential diagnosis
Testicular germ cell tumors in the postchemotherapy setting
The pathology report: staging of testicular tumors and other problematic issues
Acknowledgments
References
Diagnosis and Treatment of Testicular Cancer: A Clinician s Perspective
Abstract
Overview
Clinical stage I seminoma
Clinical stage I nonseminoma
Residual mass in advanced disease
Midline cancer of unknown primary
Summary
References
Adrenal Tumors in Adults
Abstract
Overview
Adrenal incidentaloma
Adrenal cortical adenoma
Adrenocortical carcinoma
Pheochromocytoma
References
Adrenocortical Carcinoma: A Clinician s Perspective
Abstract
Overview
Pathogenesis
Clinical
Differential considerations
Treatment and prognosis
References
Updates in Benign Lesions of the Genitourinary Tract
Abstract
Kidney
Urinary bladder
Prostate
Testis
References
Copyright
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SURGICAL PATHOLOGY CLINICS Volume 8, Number 4 December 2015 ISSN 1875-9181, ISBN-13: 978-0-323-39587-8
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Contributors
Consulting Editor
JOHN R. GOLDBLUM, MD, Chairman, Department of Anatomic Pathology, Professor of Pathology; Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio
Editor
MICHELLE S. HIRSCH, MD, PhD, Chief, Genitourinary Pathology Division, Staff Pathologist, Department of Pathology, Brigham and Women s Hospital, Associate Professor, Harvard Medical School, Boston, Massachusetts
Authors
ADEBOWALE J. ADENIRAN, MD, Associate Professor, Department of Pathology, Yale University School of Medicine, New Haven, Connecticut
LAURENCE ALBIGES, MD, PhD, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts
MAHUL B. AMIN, MD, Professor, Medical Director and Chairman, Department of Path