Restless Legs Syndrome and Movement Disorders, An Issue of Sleep Medicine Clinics

Denise Sharon

Description

Dr. Denise Sharon has put together an expert panel of authors on the topic of Restless Legs Syndrome and Movement Disorders. The comprehensive list of articles includes: Restless Legs Syndrome across the Globe, Neuroimaging in Restless Legs Syndrome, What's in the family of the RLS/WED patient?, Clinical Diagnosis and Diagnostic Criteria, Non-pharmacological management: myths vs. science, Sleep Bruxism, Leg Cramps, Hypnic Jerks, and more!

Sujets

• Médecine
• Médecine Générale
• Medical
• Neurology

Informations

• Publié par: Elsevier
• Date de parution: 17 septembre 2015
• Nombre de lectures: 0
• EAN13: 9780323395861
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Clinics Review Articles Sleep Medicine Clinics
Restless Legs Syndrome and Sleep Related Movement Disorders

Denise Sharon, MD, PhD, FAASM
Tulane University School of Medicine, New Orleans, LA, USA
ISSN  1556-407X Volume 10 • Number 3 • September 2015
Elsevier
Table of Contents
Cover image
Title page
Copyright
CME Accreditation Page
Target Audience
Learning Objectives
Accreditation
Disclosure of Conflicts of Interest
Unapproved/Off-Label Use Disclosure
To Enroll
Method of Participation
CME Inquiries/Special Needs
Forthcoming Issues
Forthcoming Issues
Recent Issues
Contributors
Consulting Editor
Editor
Authors
Preface: Restless Legs Syndrome and Sleep Related Movement Disorders
Epidemiology of Restless Legs Syndrome/Willis-Ekbom Disease
Restless Leg Syndrome Across the Globe
Key points
Background
Restless legs syndrome/Willis-Ekbom disease criteria
Africa
Asia
Europe
The Americas
Methodology in determining restless legs syndrome/Willis-Ekbom disease prevalence
Restless legs syndrome/Willis-Ekbom disease genetics and world prevalence
Summary
Pathophysiology of Restless Legs Syndrome/Willis-Ekbom Disease
Restless Leg Syndrome/Willis-Ekbom Disease Pathophysiology
Key points
Introduction
Genetics and restless leg syndrome/Willis-Ekbom disease pathophysiology
Iron pathophysiology
Consequences of iron deficiency: hypoxic pathway activation and myelin loss
Dopamine pathophysiology
Dopamine pathophysiology: basis for restless leg syndrome/Willis-Ekbom disease treatment augmentation
Other pathophysiologic findings in restless leg syndrome
Summary
Neuroimaging in Restless Legs Syndrome
Key points
Introduction
Brain MRI
Positron emission tomography
Single-photon emission computed tomography
Transcranial ultrasonography
Summary
The Molecular Genetics of Restless Legs Syndrome
Key points
Genetic epidemiology, candidate gene approaches, and linkage studies
Genome-wide association studies
Experimental studies
Summary
Diagnosis of Restless Legs Syndrome/Willis-Ekbom Disease
Diagnosis of Restless Leg Syndrome (Willis-Ekbom Disease)
Key points
Introduction
Diagnostic criteria
Special populations: pediatric and cognitively impaired
Supportive and associated clinical features to assist diagnosis
Disorders that mimic or affect the diagnostic process
Altering agents or medications
Diagnostic workup
Conclusion
The Role of Periodic Limb Movements During Sleep in Restless Legs Syndrome
Key points
Introduction
Periodic leg movements and arousals during sleep in restless legs syndrome
Differential drug treatment effects on periodic leg movements during sleep and restless legs syndrome symptoms
Periodic leg movements during sleep and transient autonomic system activations
Summary and outlook
Differential Diagnoses of Restless Legs Syndrome/Willis-Ekbom Disease
Key points
Conditions mimicking restless legs syndrome/Willis-Ekbom disease
Restless legs syndrome/Willis-Ekbom disease comorbidities (symptomatic or secondary cases)
Management of Restless Legs Syndrome/Willis-Ekbom Disease
Management of Restless Legs Syndrome/Willis Ekbom Disease
Nonpharmacologic Management of Restless Legs Syndrome (Willis-Ekbom Disease)
Key points
Introduction
Behavior modifications and lifestyle changes
Substances
Diets
Supplements
Applications and procedures
Devices
Behavioral and cognitive
Summary
Dopaminergic Therapy for Restless Legs Syndrome/Willis-Ekbom Disease
Key points
Introduction
Dopamine precursor
Nonergot dopamine agonists
Summary
Dopaminergic Augmentation in Restless Legs Syndrome/Willis-Ekbom Disease
Key points
Introduction
Clinical definition
Augmentation under dopaminergic agents
Differential diagnosis of augmentation
Managing augmentation
Summary
Toward a Definition of Quality Care for Patients with Restless Legs Syndrome
Key points
Why quality care?
How can quality care be measured?
The development of quality measures for restless legs syndrome
Restless legs syndrome quality metrics
How should these measures be used?
Management of Restless Legs Syndrome/Willis-Ekbom Disease in Hospitalized and Perioperative Patients
Key points
Introduction
Management goals
Pharmacologic strategies
Nonpharmacologic strategies
Summary/Discussion
Restless Legs Syndrome/Willis-Ekbom Disease and Growing Pains in Children and Adolescents
Key points
Introduction
Epidemiology
Pathophysiology
Clinical manifestation
Diagnosis
Consequences
Management
Prognosis
Restless Legs Syndrome/Willis-Ekbom Disease and Pregnancy
Key points
Introduction
Prevalence
Pathogenesis
Pregnancy-related risk factors for restless legs syndrome
Impact and outcomes
Management and treatment
Restless Legs Syndrome/Willis–Ekbom Disease and Periodic Limb Movements in Sleep in the Elderly with and without Dementia
Key points
Introduction
Primary restless legs syndrome/Willis–Ekbom disease in the elderly
Comorbid restless legs syndrome/Willis–Ekbom disease in the elderly
Restless legs syndrome/Willis–Ekbom disease in the cognitively impaired elderly
Summary
Restless Leg Syndrome in Neurologic and Medical Disorders
Key points
Introduction
Associated disorders
A hypothesis on the mechanism of restless leg syndrome
Interpretation of the proposed mechanism
Summary
Restless Legs Syndrome and Psychiatric Disorders
Key points
Comorbidity between psychiatric disorders and restless legs syndrome
Restless legs syndrome and subclinical psychological distress
Anxiety disorders and restless legs syndrome
Depression and restless legs syndrome
The importance of mood and anxiety disorders in the treatment of restless legs syndrome
Schizophrenia
Attention-deficit/hyperactivity disorder
Pharmacologic considerations
Summary
Living with Restless Legs Syndrome/Willis-Ekbom Disease
Key points
The impact of increasing end-stage renal disease worldwide
Epidemiology of restless legs syndrome/Willis-Ekbom disease among the patients with end-stage renal disease
Etiology of restless legs syndrome/Willis-Ekbom disease in patients with end-stage renal disease
Diagnosis of restless legs syndrome/Willis-Ekbom disease in patients with end-stage renal disease
Consideration before starting to treat restless legs syndrome/Willis-Ekbom disease in end-stage renal disease
Management of restless legs syndrome/Willis-Ekbom disease in end-stage renal disease
Pharmacologic treatment
Nonpharmacological treatment
Restless legs syndrome/Willis-Ekbom disease in end-stage renal disease patients and mortality
Restless Legs Syndrome/Willis-Ekbom Disease Morbidity
Key points
Introduction
Quality of life
Cardiovascular aspects
Sleep disruption and restless legs syndrome
Night eating and sleep-related eating disorder
Summary
Other Sleep Related Movement Disorders
Overview on Sleep Bruxism for Sleep Medicine Clinicians
Key points
Sleep bruxism clinical characteristics and diagnosis
Putative explanations for sleep bruxism
Management of sleep bruxism
Summary
Sleep-Related Leg Cramps
Key points
Prevalence
Differential diagnosis
Pathophysiology
Treatments
Future directions for research
Patient education and clinician education
Hypnic Jerks
Key points
Introduction
Methods
Summary
Copyright
ELSEVIER
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SLEEP MEDICINE CLINICS Volume 10, Number 3 September 2015, ISSN 1556-407X, ISBN-13: 978-0-323-39585-4
Editor: Patrick Manley
Developmental Editor: Donald Mumford
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