Annales de l'Institut Pasteur

France) Institut Pasteur (Paris

Sujets

• Microbiology
• Science
• Medicine

Informations

• Publié par: les_archives_du_savoir
• Nombre de lectures: 14
• Langue: English
• Poids de l'ouvrage: 38 Mo

Extrait

i
ANNALES
DE PASTEURL'INSTITUT—ARIS. L. MARETHEUX, RUE CASSETTE.IMPRIMEUR, 1,ANNALES
PASTEURDE L'INSTITUT
DE Wl.LE PATRONAGEFONDÉES sous
PAR
E. DUCLAUX
COMITÉ DE REDACTION
1
directeur de l'Institut Pasteur deD' GALMETTE, Lille;
|
~
D^ à la Faculté deCHANTEMESSE, Médecine;professeur
de FranceD"^ membre de l'InstitutLAVERAN, ;
du service deD"" L. MARTIN, directeur ;Sérothérapie
directeur de l'Institut PasteurD"" ;ROUX, j
Médecine. iD"" membre de l'Académie deVAILLARD,
I
I
TOME TRENTE-DEUXIÈME
1918
AVEC 8 PLANCHES
PARIS
ÉDITEURSMASSON ET G'%
L'ACADÉMIE DE MÉDECINELIBRAIRES DE
Saint-GermainBoulevard (6^).120,M 3^(6)N" 1JANVIER 191835« ANNÉE
ANNALES
DE
L'L\STITUT PASTEUR
THE CHEMICAL lYIECHANISIYI OF REGENERATION
LOEBJACQUESby
of the Rockefeller Institute for Médical New York.Member Research,
I
— is1 It isknown that if a or a lower animal mutilated
. plant
is oncenew take which thea place by organismgrowth may
has beenmore rendered more or less and thiscomplète, process
The of losttermed régénération organs pro-régénération.
from dormant buds near theceeds in wound,plants usually
is called forth as a of the muti-whose growth conséquence
lation. The of has been interpretedphenomenon régénération
to a or an animalin the verbal attributing plantpurely way by
orsome kind of for its form
)feeling proper (Noll's morphœstesia
of a thethe in theprésence organism mystical agency,by
« ». Weismann out that hasentelechy pointed régénération
werea sélective value since forms endowed with this power
to amore to survive. Others ascribedlikely
« » and similaretfect of the wound. Thèsestimulating
of need not ouraltempts explaining régénération occupy
since hâve notled to scientific results.attention they
The earlier Bonnet and had a moreDuhamel,biologists,
chemical attitude towards the that aproblem, assuming plant
contained two kinds of an one which carriedsap, ascending
shoot and a onematerial for the production, descending
material for root If the is eut off incarrying production. apex
a the near the eut will induce
plant, ascending sap collecting
1DE L'INSTITUT PASTEUR2 ANNALES
from and if llie root is eutIhe of shoots Ihebuds, o(î,growth
Ihc at the base will indiice therecolleition of doscending sap
of roots. Sachs thnse views andthe accepted genera-growth
as différentlized thcm by assuming many spécifie organ-
substances in Ihe as there areplant (or animal) organs.forming
substances were said to be in minuteThèse spécifie présent
This bas received someassumptionquantilies only. support
on the elfect of internairécent observations sécrétions^by
the
espeeially thyroid gland.
onIn bis and heteromor-early experiments régénération
the vvriter was able to outin animais that thephosis point
chemical of Duhamel and Sachs harmo-viewpoint Bonnet,
well with his observations. Thus he hadnized foundvery
if a is eut from a stem of Tuhularia andthat pièce (a hydroid)
a head willin sea form at eitherwaler, (hydranth)suspended
the but the head will form much moreend of atstem, rapidly
the oral than atthe aboral end of the the différencepièce; may
few to a few weeks.amount from a of thedays Suppression
formation at the oral end withdrawal ofhead at(by oxygen
that accelerated the formation of the head at the aboralend)
latter often formedso that the as as the oral head inend, early
the with normal This is onpièces oxygen supply. intelligible
the that the head formation is determined sub-assumption by
flowstances which towards the oral end of an excisednormally
of stem until a head bas been and that after-formed,pièce
vvards the direction of the flow is and that if thereversed;
of a head at the oral end isformation the with-suppressed by
drawal of at this the flow is reversed from theend,oxygen
and a head can at the aboral end asbeginning develop rapidly
as the head at the oral end can under normal conditions. This
conclusion eould be submitted to a test an excisedby ligaturing
of stem of Tuhularia between the two ends.pièce anywhere
This should the flow of head-ligature interrupt thehypothetical
substances from the aboral towards the oral andforming end,
hence should abolish the cause for the retardation of the head
formation at the aboral end and this was tofound be true
; by
Godlewski as well as the writerby (1).
J. LaLoEn, de la 1914 et La(1) conception mécanique vie, Paris, dynamique
des de la 1908 Félixphe'no?nhies vie, Paris, (libi'airie Alcan).