Computational Simulation of Trabecular Bone Distribution around Dental Implants and the Influence of Abutment Design on the Bone Reaction for Implant-Supported Fixed Prosthesis [Elektronische Ressource] / Istabrak Hasan

Istabrak Hasan

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Informations

• Publié par: rheinische_friedrich-wilhelms-universitat_bonn
• Publié le: 01 janvier 2011
• Nombre de lectures: 6
• Langue: English
• Poids de l'ouvrage: 23 Mo

Extrait

Computational Simulation of Trabecular Bone Distribution
around Dental Implants and the Influence of Abutment Design
on the Bone Reaction for Implant-Supported Fixed Prosthesis





Dissertation
zur
Erlangung des Doktorgrades (Dr. rer. nat.)
der
Mathematisch-Naturwissenschaftlichen Fakultät
der
Rheinischen Friedrich-Wilhelms-Universität Bonn




Vorgelegt von
Istabrak Hasan
Aus
Bagdad, Irak

Bonn, Mai 2011




Angefertigt mit Genehmigung der Mathematisch-Naturwissenschaftlichen
Fakultät der Rheinischen Friedrich-Wilhelms-Universität Bonn



















1. Gutachter: Prof. Dr. rer. nat. Christoph Bourauel
2. Gutachter: Prof. Dr. Kai-Thomas Brinkmann
Tag der Promotion: 31.08.2011
Erscheinungsjahr: 2011



Table of Content

ACKNOWLEDGMENT ................................................................................. VII
ABSTRACT .....................................................................................................8
1. INTRODUCTION ....................................................................................10
2. REVIEW OF THE LITERATURE............................................................12
2.1. Bone Biology.....................................................................................12
2.1.1. Cancellous Bone Architecture......................................................13
2.1.2. Bone Modelling and Remodelling ................................................14
2.1.3. Bone Remodelling and Mechanical Stimuli..................................17
2.1.4. Experimental Investigation of Bone Remodelling.........................19
2.1.5. Computer Simulation of Bone Remodelling .................................20
2.1.6. Bone Remodelling Theories.........................................................23
2.1.6.1. Bone Remodelling based on the Concept of Micro-Damage....23
2.1.6.2. Strain Theory of Adaptive Elasticity..........................................24
2.1.6.3. Strain Energy Density Theory of Adaptive Remodelling...........26
2.1.6.4. Theory of Self Optimisation ......................................................28
2.2. Bone Quality and Verifying Methods...............................................30
2.3. Fracture Healing and Bone Repair around Implants......................31
2.4. Replacing partially Edentulous Ridge by Fixed Prosthesis ..........34
2.4.1. Dental Implant Design..................................................................34
2.4.2. Abutment Design in the Anterior Maxilla ......................................34
2.4.3. Implant-supported Fixed Prostheses............................................35
3. MATERIALS AND METHODS ...............................................................37
3.1. Mechanical Investigation of Different Implant and Abutment
Designs: Experimental, Numerical and Clinical Aspects .........................37
3.1.1. Implant Design and Geometry .....................................................37
®3.1.1.1. Tiolox Implants........................................................................37
©3.1.1.2. tioLgic Implants.......................................................................37
3.1.2. Abutment Design..........................................................................38
3.1.3. Fixed Partial Prosthesis Models...................................................40
3.1.4. Experimental Protocol..................................................................44
3.1.4.1. Implant Insertion and Measurement Set-up..............................45
3.1.4.2. Reconstruction and Development of Numerical Models...........47
3.1.5. Clinical Protocol and Study Design ..............................................48
3.1.5.1. Statistical Analysis....................................................................49
3.2. Bone Remodelling Theory................................................................51
iii
3.2.1. Bone Remodelling Simulation ......................................................51
3.2.2. Sensitivity Test of the Applied Theory..........................................55
3.2.2.1. Sensitivity Test: Element Size ..................................................56
3.2.2.2. Sensitivity Test: Boundary Conditions ......................................58
3.2.2.3. Sensitivity Test: Applying Remodelling Parameters based on
Mechanostat Theory.................................................................58
3.2.2.4. Sensitivity Test: Implant Loading Conditions ............................59
3.2.2.5. Sensitivity Test: Cancellous Bone Stiffness..............................59
3.2.2.6. Sensitivity Test: Elastic Modulus-Density Relation ...................59
3.2.2.7. Sensitivity Test: Bone Qualities ................................................60
3.2.2.8. Sensitivity Test: Implant Geometry...........................................60
3.2.3. Validation of the Computational Trabecular Geometry around an
Implant by Using 6-year CT-Images.............................................61
3.2.4. Influence of Soft Tissue Thickness on Bone Remodelling
Simulation ....................................................................................62
3.2.4.1. Remodelling Model Including Soft Tissue Interface..................64
3.2.4.2. Finite Element Models of Different Healing Phases..................64
3.2.4.3. Radiographical Trabecular Structure at Different Healing Phases
.................................................................................................66
4. RESULTS...............................................................................................68
4.1. Mechanical Investigation of Different Implant and Abutment
Designs: Experimental, Numerical and Clinical Aspects ..............68
4.1.1. Fixed Partial Prosthesis Models...................................................69
4.1.1.1. Immediately Loaded Condition .................................................69
4.1.1.2. Osseointegrated Condition .......................................................69
4.1.2. Experimental Study of the Relation of Implant Primary Stability to
the Implant Geometry and Abutment Design ...............................75
4.1.2.1. Numerical Results of Experimentally Studied Samples............81
4.1.3. The Relation of Crestal Bone Resorption to the Abutment Design
Used with Implant-Supported Fixed Partial Prosthesis ................85
4.1.3.1. Statistical Analysis....................................................................85
4.2. Bone Remodelling Theory................................................................89
4.2.1. Sensitivity Test of the Applied Theory..........................................89
4.2.1.1. Sensitivity Test: Element Size ..................................................89
4.2.1.2. Sensitivity Test: Boundary Conditions ......................................90
4.2.1.3. Sensitivity Test: Applying Remodelling Parameters based on
Mechanostat Theory...............................................................100
4.2.1.4. Sensitivity Analysis: Occlusal Loads.......................................100
4.2.1.5. Sensitivity Test: Cancellous Bone Stiffness............................107
4.2.1.6. Sensitivity Test: Young’s Modulus-Density Relation...............108
4.2.1.7. Sensitivity Test: Bone Qualities ..............................................109
4.2.1.8. Sensitivity Test: Implant Geometry.........................................110
4.2.2. Validation of the Computational Trabecular Geometry around an
Implant by Using 6-year CT-Images...........................................111
4.2.3. The influence of Soft Tissue Thickness on Bone Remodelling
Simulation ..................................................................................112
4.2.4. Remodelling Model Including Soft Tissue Interface ...................112
iv
5. DISCUSSION .......................................................................................118
5.1. Mechanical Investigation of Different Implant and Abutment
Designs: Experimental, Numerical and Clinical Aspects ............118
5.1.1. Numerical Investigation of Fixed Partial Prosthesis FPP ...........118
5.1.2. Experimental and the Associated Numerical Investigations of
Different Implant and Abutment Designs....................................121
5.1.3. The Relation of Crestal Bone Resorption to the Abutment Design
used in Implant-Supported Fixed Partial Prosthesis...................126
5.2. Bone Remodelling Simulation .......................................................128
5.2.1. Sensitivity Analysis.....................................................................128
5.2.2. Validation of the Computational Trabecular Geometry around an
Implant by Using 6-year CT-Images...........................................135
5.2.3. Remodelling Model Including Soft Tissue Interface ...................135
5.2.4. Future Perspectives ...................................................................137
REFERENCES ............................................................................................1