Costs and consequences of large-scale vector control for malaria

Yukich, Lengeler Christian, Tediosi Fabrizio, Brown Nick, Mulligan Jo-Ann, Chavasse Des, Stevens Warren, Justino John, Conteh Lesong, Maharaj Rajendra, Goodman Catherine, Mcguire David, Urrutia Juan, Sakho Fana, Hanson Kara, Sharp Brian, Erskine Marcy, Mueller, Wiseman Virginia, Ghebremeskel Tewolde, Zerom Mehari

Description

Five large insecticide-treated net (ITN) programmes and two indoor residual spraying (IRS) programmes were compared using a standardized costing methodology. Methods Costs were measured locally or derived from existing studies and focused on the provider perspective, but included the direct costs of net purchases by users, and are reported in 2005 USD. Effectiveness was estimated by combining programme outputs with standard impact indicators. Findings Conventional ITNs: The cost per treated net-year of protection ranged from USD 1.21 in Eritrea to USD 6.05 in Senegal. The cost per child death averted ranged from USD 438 to USD 2,199 when targeting to children was successful. Long-lasting insecticidal nets (LLIN) of five years duration: The cost per treated-net year of protection ranged from USD 1.38 in Eritrea to USD 1.90 in Togo. The cost per child death averted ranged from USD 502 to USD 692. IRS: The costs per person-year of protection for all ages were USD 3.27 in KwaZulu Natal and USD 3.90 in Mozambique. If only children under five years of age were included in the denominator the cost per person-year of protection was higher: USD 23.96 and USD 21.63. As a result, the cost per child death averted was higher than for ITNs: USD 3,933–4,357. Conclusion Both ITNs and IRS are highly cost-effective vector control strategies. Integrated ITN free distribution campaigns appeared to be the most efficient way to rapidly increase ITN coverage. Other approaches were as or more cost-effective, and appeared better suited to "keep-up" coverage levels. ITNs are more cost-effective than IRS for highly endemic settings, especially if high ITN coverage can be achieved with some demographic targeting.

Informations

• Publié par: biomed
• Publié le: 01 janvier 2008
• Nombre de lectures: 11
• Langue: English

Extrait

Malaria Journal

BioMedCentral

Open Access Research Costs and consequences of large-scale vector control for malaria 1 11,2 1,3 Joshua O Yukich, Christian Lengeler*, Fabrizio Tediosi, Nick Brown, 4 56 7 JoAnn Mulligan, Des Chavasse, Warren Stevens, John Justino, 1,4 89 4 Lesong Conteh, Rajendra Maharaj, Marcy Erskine, Dirk H Mueller, 4 1010 Virginia Wiseman, Tewolde Ghebremeskel, Mehari Zerom, 4,11 1213 Catherine Goodman, David McGuire, Juan Manuel Urrutia, 14 4 Fana Sakho, Kara Hansonand Brian Sharp

1 2 Address: Departmentof Public Health and Epidemiology, Swiss Tropical Institute, P.O. Box, 4002 Basel, Switzerland,Centre for Research on 3 Health and Social Care Management, Università Bocconi, Milan, Italy,ITN Cell, National Malaria Control Programme, Ministry of Health, Dar 4 Es Salaam, Tanzania,Health Economics and Financing Programme, London School of Hygiene and Tropical Medicine, Keppel Street, London, 5 67 WC1E 7HT, UK,Population Services International, Nairobi, Kenya,Medical Research Council Laboratories, Banjul, Gambia,Population 8 Services International, Blantyre, Malawi,Malaria Lead Programme, Medical Research Council of South Africa, Durban, KwaZuluNatal, South 9 10 Africa, CanadianRed Cross, Ottawa, Ontario, Canada,National Malaria Control Programme, Ministry of Health, P.O. Box 212, Asmara, Eritrea, 11 1213 KEMRI/Wellcome Trust Programme, PO Box 43640, Nairobi, Kenya,Abt Associates Inc., Bethesda, MD, USA,NetMark Partnership, Academy 14 for Educational Development, Johannesburg, South Africa andNetMark Partnership, Academy for Educational Development, Dakar, Senegal

Email: Joshua O Yukich  [e-mail]; Christian Lengeler*  [e-mail]; Fabrizio Tediosi  [e-mail]; Nick Brown  [e-mail]; JoAnn Mulligan  [e-mail]; Des Chavasse  [e-mail]; Warren Stevens  [e-mail]; John Justino  [e-mail]; Lesong Conteh  [e-mail]; Rajendra Maharaj  [e-mail]; Marcy Erskine  [e-mail]; Dirk H Mueller  [e-mail]; Virginia Wiseman  [e-mail]; Tewolde Ghebremeskel  [e-mail]; Mehari Zerom  [e-mail]; Catherine Goodman  [e-mail]wellcome.org; David McGuire  [e-mail]; Juan Manuel Urrutia  [e-mail]; Fana Sakho  [e-mail]; Kara Hanson  [e-mail]; Brian Sharp  [e-mail] * Corresponding author

Published: 17 December 2008Received: 27 October 2008 Accepted: 17 December 2008 Malaria Journal2008,7:258 doi:10.1186/1475-2875-7-258 This article is available from: http://www.malariajournal.com/content/7/1/258 © 2008 Yukich et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract Background:Five large insecticide-treated net (ITN) programmes and two indoor residual spraying (IRS) programmes were compared using a standardized costing methodology. Methods:Costs were measured locally or derived from existing studies and focused on the provider perspective, but included the direct costs of net purchases by users, and are reported in 2005 USD. Effectiveness was estimated by combining programme outputs with standard impact indicators. Findings:Conventional ITNs: The cost per treated net-year of protection ranged from USD 1.21 in Eritrea to USD 6.05 in Senegal. The cost per child death averted ranged from USD 438 to USD 2,199 when targeting to children was successful. Long-lasting insecticidal nets (LLIN) of five years duration: The cost per treated-net year of protection ranged from USD 1.38 in Eritrea to USD 1.90 in Togo. The cost per child death averted ranged from USD 502 to USD 692.

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