Genetic association analysis with survival phenotypes [Elektronische Ressource] / by Andrea Martina Müller

From The Institute of Medical Information Processing, Biometry, and Epidemiology of the Ludwig-Maximilians-Universität, Munich, Germany Chair of Epidemiology: Prof. Dr. Dr. H.-Erich Wichmann and The Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH) Director: Prof. Dr. Dr. H.-Erich Wichmann Genetic association analysis with survival phenotypes Thesis Submitted for a Doctoral degree in Human Biology at the Faculty of Medicine Ludwig-Maxiimilians-University, Munich, Germany by Andrea Martina Müller From Munich, Germany 2009 With approval of the Medical Faculty of the University of Munich First Reviewer: Prof. Dr. Dr. H.-Erich Wichmann Second Reviewer: Prof. Dr. Ulrich Mansmann Prof. Dr. Elke Holinski-Feder Co-supervision: Dr. Iris M. Heid Dean: Prof. Dr. med. Dr. h.c. M. Reiser, FACR, FRCR Date of the oral examination: 17.03.2009 i Acknowledgements In first instance I want to thank Prof. Dr. Dr. H.-Erich Wichmann, head of the Institute of Epidemiology at the Helmholtz Zentrum München and Chair of Epidemiology at the Institute of Medical Information Processing, Biometry, and Epidemiology of the University of Munich, who not only encouraged and enabled the work on this thesis at his institute, but also offered a variety of opportunities to work in the field of genetic epidemiology on exciting projects with experienced partners.