In vitro corrosion of ZEK100 plates in Hank
14 pages
English
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In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution

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14 pages
English

Description

In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery. Methods ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD. Results The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates. Conclusions The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior.

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Publié le 01 janvier 2012
Nombre de lectures 31
Langue English
Poids de l'ouvrage 5 Mo

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Waizyet al.BioMedical Engineering OnLine2012,11:12 http://www.biomedicalengineeringonline.com/content/11/1/12
R E S E A R C HOpen Access In vitro corrosion of ZEK100 plates in Hanks Balanced Salt Solution 1* 11 11 2 Hazibullah Waizy, Andreas Weizbauer , Christian Modrejewski , Frank Witte , Henning Windhagen , Arne Lucas , 3 23 4,56 Marc Kieke , Berend Denkena , Peter Behrens , Andrea MeyerLindenberg, FriedrichWilhelm Bachand 1,7 Fritz Thorey
* Correspondence: Hazibullah. Waizy@ddhgruppe.de 1 Department of Orthopedic Surgery, Hannover Medical School, AnnavonBorriesStr.17, 30625 Hannover, Germany Full list of author information is available at the end of the article
Abstract Background:In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery. Methods:ZEK100 plates were examined in this in vitro study with Hanks Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD. Results:The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates. Conclusions:The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior. Keywords:Magnesium alloy, Corrosion, Plates, in vitro study
Background The first published application of a plate for fracture fixation was 1886 by Carl Hans th mann [1]. It was not until the beginning of the 20century when plates as osteosynth esis systems was spread due to the works of William Arbuthnot Lane and Albin Lambotte. In 1907 Lane, a British surgeon, introduced perforated steel plates for use in internal fixation [2]. Lambotte was one of the first to apply pure magnesium plates in a clinical case to stabilize a fracture in a young man. After implantation he observed extensive subcutaneous gas cavities and local swelling caused by rapid degradation [3]. In recent years, new innovative magnesium alloys are being intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and
© 2012 Waizy et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.