RNA interference as a tool to prevent acute and chronic enterovirus myocarditis der Fakultät für Biologie der Eberhard Karls Universität Tübingen zur Erlangung des Grades eines Doktors der Naturwissenschaften von Giorgia Racchi aus Triest, Italien vorgelegte Dissertation 2007 Tag der mündlichen Prüfung: 12. 06. 2007 Dekan: Prof. Dr. F. Schöffl 1. Berichterstatter: PD Karin Klingel 2. Berichters Prof. Dr. rer.nat. Dr. h.c. Nikolaus Blin TO MY PARENTS ’’This deserves to be inquired into’’ Bell C. 1844 Acknowledgements I thank the Department of Molecular Pathology, University Hospital of Tuebingen, for giving me hospitality and allowing me to carry out this interesting Ph. D research. In the first place I would like to recall my gratitude to Dr. Gabriele Grassi for his supervision, outstanding advice, constant help and moral support from the very early stage of this research and throughout these years. In addition I want to thank for valuable contribution Dr. R. Kandolf for taking care of my situation and Dr. K. Klingel for finding financial support, thus giving me the possibility to complete the Ph. D. program, and for using her time to read the thesis and giving her critical comments. Many thanks to Dr. N.
RNA interference as a tool to prevent acute and chronic enterovirus myocarditis der Fakultät für Biologie der Eberhard Karls Universität Tübingen zur Erlangung des Grades eines Doktors der Naturwissenschaften von Giorgia Racchiaus Triest, Italien vorgelegte D i s s e r t a t i o n
2007
Tag der mündlichen Prüfung: Dekan:1. Berichterstatter: 2. Berichterstatter:
12. 06. 2007 Prof. Dr. F. Schöffl PD Dr. Karin Klingel Prof. Dr. rer.nat. Dr. h.c. Nikolaus Blin
TO
MY
PARENTS
’’This deserves to be inquired into ’’ Bell C. 1844