Strukturelle und Biochemische Charakterisierung der Humanen Serin Protease HtrA1 [Elektronische Ressource] / Linda Trübestein. Gutachter: Michael Ehrmann ; Peter Bayer. Betreuer: Michael Ehrmann

Truebestein

Description

Structural and Biochemical Characterization of the Human Serine Protease HtrA1 Inaugural-Dissertation zur Erlangung des Doktorgrades Dr. rer. nat. der Fakultät für Biologie und Geografie an der Universität Duisburg-Essen vorgelegt von Linda Trübestein aus Berlin April 2010 Gutachter: Prof. Michael Ehrmann, Prof. Peter Bayer Prüfungsdatum: 18.06.2010 III Parts of this work are included in the bfloilclaotwionngs :p u Tennstaedt, A., Truebestein, L., Hauske, tP.,, N.S,c hImirlde, I., Kaiser, M., Brandt, AR., Sickmann, Egensperger, R., Baldi, A., Dehmelt, L. u ndM .,E hr„HmatrnAn1 is a tau protease.“ (in revision in PNAS) Truebestein, L., Tennstaedt, A., Krojer, ,T .,P. ,H aKuasikeser, M., Clausen, T., and Ehrmann, M., „Substrate binding remodels active site do fr eHgturlAa1 teasn protease activity.” (submitted to Nat Struc & Mol Biol) V Acknowledgements First of all I would like to thank Micfhoare lh iEsh rcmaonsnt ant support and supervision during my PhD. Thanks for giving me the chance to wso rvke roy n itnhtieresting project and for allu the trust yohad in me. I am thankful to all the members in the E hfromra nnc reLaatbing a very nice working atmosphere, for all the discussions and the nice time we had. I want to thank Tim Clausen for giving m ec htahenc eg rteoa twork in his lab and for always giving me the feeling that I am very welcome.

Sujets

• Biologie

Informations

• Publié par: universitat_duisburg-essen
• Publié le: 01 janvier 2011
• Nombre de lectures: 21
• Langue: English
• Poids de l'ouvrage: 10 Mo

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