The role of RIP-1 and cIAPs in apoptotic and non-apoptotic signalling via TLR3 and death receptors [Elektronische Ressource] / von Maria Alekseevna Feoktistova

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The role of RIP-1 and cIAPs in apoptotic and non-apoptotic signalling via TLR3 and death receptors Dissertation zur Erlangung des akademischen Grades Doctor rerum naturalium (Dr. rer. nat.) genehmigt durch die Fakultät für Naturwissenschaften der Otto-von-Guericke-Universität Magdeburg von Diplom-Genetikerin Maria Alexeevna Feoktistova geboren am 4.11.1982 in Moskau, Russland Gutachter: Prof. Dr. Martin Leverkus . Henning Walczak eingereicht am: 23.08.2010 verteidigt am: 7.03.2011 Diplom Genetikerin Feoktistova Maria Alexeevna The role of RIP-1 and cIAPs in apoptotic and non-apoptotic signalling via TLR3 and death receptors Acknowledgements Many thanks to: Dr. Peter Geserick and Prof. Martin Leverkus for advice and supervision Dr. Philip Diessenbacher, Beate Kellert, Barbara Kehler, Mike Hupe, Shyam Kavuri for help and support This thesis was supported by the DFG graduate program GRK 1167. I am grateful to the members of the GRK, in particular to the two charis, Prof. Michael Naumann and Prof. Eckart D. Gundelfinger. 2Diplom Genetikerin Feoktistova Maria Alexeevna The role of RIP-1 and cIAPs in apoptotic and non-apoptotic signalling via TLR3 and death receptors Summary Skin cancers, like squamous cell carcinoma (SCC), which belongs to the most frequent tumors world wide, require novel strategies for treatment, since most malignant cancer cells resist current anti-tumour agents.

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• Wissenschaft

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• Publié par: otto-von-guericke-universitat_magdeburg
• Publié le: 01 janvier 2011
• Nombre de lectures: 23
• Langue: English
• Poids de l'ouvrage: 3 Mo

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