Tuberculosis and HIV co-infection: its impact on quality of life

Deribew Amare, Tesfaye Markos, Hailmichael Yohannes, Negussu Nebiyu, Daba Shallo, Wogi Ajeme, Belachew Tefera, Apers Ludwig, Colebunders, Colebunders Robert

Description

- Very little is known about the quality of life of tuberculosis (TB) and HIV co-infected patients. In this study in Ethiopia, we compared the quality of life HIV positive patients with and without TB. Methods- A cross sectional study was conducted from February to April, 2009 in selected hospitals in Oromiya Regional state, Ethiopia. The study population consisted of 467 HIV patients and 124 TB/HIV co-infected patients. Data on quality of life was collected by trained nurses through face to face interviews using the short Amharic version of the World Health Organization Quality of Life Instrument for HIV clients (WHOQOL HIV). Depression was assessed using a validated version of the Kessler scale. Data was collected by trained nurses and analyzed using SPSS 15.0 statistical software. Results TB/HIV co-infected patients had a lower quality of life in all domains as compared to HIV infected patients without active TB. Depression, having a source of income and family support were strongly associated with most of the Quality of life domains. In co-infected patients, individuals who had depression were 8.8 times more likely to have poor physical health as compared to individuals who had no depression, OR = 8.8(95%CI: 3.2, 23). Self-stigma was associated with a poor quality of life in the psychological domain. Conclusion- The TB control program should design strategies to improve the quality of life of TB/HIV co-infected patients. Depression and self-stigma should be targeted for intervention to improve the quality of life of patients.

Informations

• Publié par: biomed
• Publié le: 01 janvier 2009
• Nombre de lectures: 14
• Langue: English

Extrait

Health and Quality of Life Outcomes

BioMedCentral

Open Access Research Tuberculosis and HIV coinfection: its impact on quality of life 1 2 3 Amare Deribew* , Markos Tesfaye , Yohannes Hailmichael , 4 5 5 6 Nebiyu Negussu , Shallo Daba , Ajeme Wogi , Tefera Belachew , 7 7,8 Ludwig Apers and Robert Colebunders

1 2 Address: Department of Epidemiology, Jimma University, Jimma, Ethiopia, Department of Psychiatry, Jimma University, Jimma, Ethiopia, 3 4 Department of Health Service Management, Jimma University, Jimma, Ethiopia, Malaria Control Program, Somali regional Health Bureau, Jijiga, 5 6 Ethiopia, HIV Prevention and Control office, Oromiya Regional Health Bureau, Addis Ababa, Ethiopia, Department of Population and Family 7 Health, Jimma University, Jimma, Ethiopia, Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, 8 Belgium and Department of Epidemiology and Social Medicine, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1 2610 Antwerpen, Belgium Email: Amare Deribew*  [e-mail]; Markos Tesfaye  Tesfaye[e-mail]; Yohannes Hailmichael  [e-mail]; Nebiyu Negussu  [e-mail]; Shallo Daba  [e-mail]; Ajeme Wogi  [e-mail]; Tefera Belachew  [e-mail]; Ludwig Apers  [e-mail]; Robert Colebunders  [e-mail] * Corresponding author

Published: 29 December 2009 Received: 16 September 2009 Accepted: 29 December 2009 Health and Quality of Life Outcomes2009,7:105 doi:10.1186/147775257105 This article is available from: http://www.hqlo.com/content/7/1/105 © 2009 Deribew et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract Background:Very little is known about the quality of life of tuberculosis (TB) and HIV co infected patients. In this study in Ethiopia, we compared the quality of life HIV positive patients with and without TB. Methods:A cross sectional study was conducted from February to April, 2009 in selected hospitals in Oromiya Regional state, Ethiopia. The study population consisted of 467 HIV patients and 124 TB/HIV coinfected patients. Data on quality of life was collected by trained nurses through face to face interviews using the short Amharic version of the World Health Organization Quality of Life Instrument for HIV clients (WHOQOL HIV). Depression was assessed using a validated version of the Kessler scale. Data was collected by trained nurses and analyzed using SPSS 15.0 statistical software. Results:TB/HIV coinfected patients had a lower quality of life in all domains as compared to HIV infected patients without active TB. Depression, having a source of income and family support were strongly associated with most of the Quality of life domains. In coinfected patients, individuals who had depression were 8.8 times more likely to have poor physical health as compared to individuals who had no depression, OR = 8.8(95%CI: 3.2, 23). Selfstigma was associated with a poor quality of life in the psychological domain.

Conclusion:The TB control program should design strategies to improve the quality of life of TB/HIV coinfected patients. Depression and selfstigma should be targeted for intervention to improve the quality of life of patients.

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