Cardiac Resynchronization Therapy: State of the Art, An Issue of Cardiac Electrophysiology Clinics

Luigi Padeletti

Description

The latest developments in the field of Cardiac Resynchronization Therapy are featured in this issue of Cardiac Electrophysiology Clinics. The issue includes more than 20 articles in the following areas: heart failure; cost of heart failure; ventricular dissynchrony and resynchronization; assessment of dissynchrony; indication for CRT implantation; implantation technique; measures to improve CRT benefit on AF patients; and many more.

Sujets

• Médecine
• Spécialités médicales
• Médecine Générale
• Medical
• Cardiology

Informations

• Publié par: Elsevier
• Date de parution: 07 janvier 2016
• Nombre de lectures: 0
• EAN13: 9780323402392
• Langue: English
• Poids de l'ouvrage: 3 Mo

Extrait

Cardiac Resynchronization Therapy: State of the Art
Cardiac Electrophysiology Clinics
Editors
Luigi Padeletti, MD
Speciality School in Cardiovascular Diseases, University of Firenze, Firenze, Italy
Martina Nesti, MD
Electrophysiology and Pacing Centre, Heart and Vessels Department, University of Firenze, Firenze, Italy
Giuseppe Boriani, MD, PhD
Institute of Cardiology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, S.Orsola-Malpighi University Hospital, Bologna, Italy
Consulting Editors
Ranjan K. Thakur

Andrea Natale

Clinics Review Articles

www.cardiacEP.theclinics.com

December 2015 Volume 7 Number 4
Table of Contents
Cover image
Title page
Copyright
Contributors
Consulting Editors
Editors
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Foreword. Cardiac Resysnchronization Therapy: State of the Art
Preface. Cardiac Resynchronization Therapy: State of the Art
Letter to the Editor:. Arrhythmogenic Potential of Acute Idiopathic Pericarditis
References
Heart Failure
Understanding Heart Failure
Key points
Introduction
Pathophysiology
Cause of heart failure
Current approach to heart failure staging
Current approach to heart failure treatment
Pharmacologic therapy
Device therapy
Advanced therapies
Biomarker assessment in heart failure
The future
Summary
References
Cost of Heart Failure
Containing the Cost of Heart Failure Management: A Focus on Reducing Readmissions
Key points
Readmissions
Contributors to excessive readmissions
Predicting readmissions
Strategies to reduce readmission
Alternatives to hospitalization
Detecting preclinical heart failure exacerbation
Controversies regarding readmission reduction
References
Ventricular Dyssynchrony and Resynchronization: From Bench to Bedside
Cellular and Molecular Aspects of Dyssynchrony and Resynchronization
Key points
Introduction: cardiac dyssynchrony and resynchronization therapy
Beyond left ventricular mechanics
Myocyte function, calcium handling, and -adrenergic signaling
Ion channels
Myofilament function and structure
Mitochondria, bioenergetics, and metabolomics
Circulating indicators of dyssynchrony and resynchronization therapy
Future directions
References
Exploring the Electrophysiologic and Hemodynamic Effects of Cardiac Resynchronization Therapy: From Bench to Bedside and Vice Versa
Key points
Introduction
Electromechanics of dyssynchrony
Electrophysiologic effects of cardiac resynchronization therapy
Acute hemodynamic effects of cardiac resynchronization therapy
Long-term effects of cardiac resynchronization therapy
Pacing location
Myocardial scarring
Multiple pacing sites
Endocardial pacing
Optimization of timing of pacing
Summary
References
Assessment of Dyssynchrony
Newer Echocardiographic Techniques in Cardiac Resynchronization Therapy
Key points
Expanding understanding of dyssynchrony
Strain imaging to guide placement of the left ventricular lead
Echocardiographic dispersion, dyssynchrony, and arrhythmias
Summary
References
The Role of Cardiovascular Magnetic Resonance in Cardiac Resynchronization Therapy
Key points
Introduction
Cardiac function and cause of cardiomyopathy
Cardiovascular magnetic resonance in risk stratification
Cardiovascular magnetic resonance for guiding cardiac resynchronization therapy implantation
Cardiovascular magnetic resonance after device implantation
Summary
References
Implantation and Extraction Technique
Coronary Sinus Lead Positioning
Key points
Introduction
Targeting left ventricular lead placement
Multisite and multipoint pacing
Summary
References
Robotic-Assisted Left Ventricular Lead Placement
Key points
Introduction
Identifying the optimal pacing site
Conventional approach to cardiac resynchronization therapy
Surgical approach to cardiac resynchronization therapy
Summary
References
Coronary Sinus Lead Extraction
Key points
Introduction
Indications for coronary sinus lead extraction
Training and facilities
Preprocedural considerations
Facility requirements
Technique of coronary sinus lead extraction
Results of coronary sinus lead extraction
Complications of coronary sinus lead extraction
Reimplantation
Active fixation coronary sinus lead extraction
Coronary sinus defibrillation coils
Alternatives to coronary sinus lead extraction
Future directions
References
Indication for CRT Implantation
Cardiac Resynchronization Therapy: An Overview on Guidelines
Key points
Introduction
Cardiac resynchronization therapy as an effective treatment in heart failure
Guidelines on cardiac resynchronization therapy
Recommendations for cardiac resynchronization therapy with regard to patients in sinus rhythm with moderate to severe heart failure
Recommendations for cardiac resynchronization therapy with regard to patients in sinus rhythm with mild heart failure
Recommendations for cardiac resynchronization therapy with regard to patients with permanent atrial fibrillation and left ventricular dysfunction/heart failure
Patients already implanted with a conventional pacemaker or implantable cardioverter defibrillator: indications for upgrade to a cardiac resynchronization therapy device
Patients with conventional pacemaker indications and left ventricular dysfunction/heart failure: indications for implant of a cardiac resynchronization therapy device
Indications to implant a cardiac resynchronization therapy pacemaker versus a cardiac resynchronization therapy defibrillator device in candidates to cardiac resynchronization therapy in the setting of primary prevention of sudden death
Beyond guidelines: definition of appropriate use criteria for cardiac resynchronization therapy
From guidelines to the real world : heterogeneity in use of cardiac resynchronization therapy
Summary
References
Why the Authors Use Cardiac Resynchronization Therapy with Defibrillators
Key points
Introduction
The case for cardiac resynchronization therapy plus defibrillator
Summary
References
Why We Have to Use Cardiac Resynchronization Therapy-Pacemaker More
Key points
Do all heart failure patients with ejection fraction less than 35% need an implantable cardioverter defibrillator?
Is the clinical superiority of cardiac resynchronization therapy- defibrillator compared with cardiac resynchronization therapy-pacemaker clearly established?
Meta-analyses
Real life registries comparing cardiac resynchronization therapy-pacemaker and cardiac resynchronization therapy-defibrillator
Decreasing need of implantable cardioverter defibrillator therapy after cardiac resynchronization therapy
Cost and cost-effectiveness of cardiac resynchronization therapy-defibrillator versus cardiac resynchronization therapy-pacemaker
Safety issues and risk-benefit profile of cardiac resynchronization therapy-defibrillator versus cardiac resynchronization therapy-pacemaker
What do the guidelines say?
Summary
References
Cardiac Resynchronization Therapy in Women
Key points
Introduction
Observational studies
Analyses from databases
Analyses from registries
Post hoc analyses of randomized controlled clinical trials
Meta-analyses
Summary
References
How to Improve CRT Benefit on Atrial Fibrillation Patients
Atrial Fibrillation During Cardiac Resynchronization Therapy
Key points
Introduction
Detrimental effect of atrial fibrillation on response to cardiac resynchronization therapy
Studies investigating the beneficial effect of cardiac resynchronization therapy in the presence of atrial fibrillation
The role of atrioventricular junction ablation
Recommendations
Summary
References
Atrioventricular Node Ablation
Key points
What are the interactions between atrial fibrillation and heart failure (atrial fibrillation begets heart failure and vice versa)?
What are the tools to treat atrial fibrillation in heart failure?
Medical therapy for rate control in permanent atrial fibrillation
What are the interactions between atrial fibrillation and ca rdiac resynchronization therapy ?
The importance of maximized biventricular pacing
Summary
References
How to Improve Cardiac Resynchronization Therapy Benefit in Atrial Fibrillation Patients: Pulmonary Vein Isolation (and Beyond)
Key points
Introduction
Atrial fibrillation and heart failure
Atrial fibrillation and cardiac resynchronization therapy
Studies on atrial fibrillation ablation in patients with heart failure
Ablation approach
Summary
References
Response to CRT
The Role of Atrioventricular and Interventricular Optimization for Cardiac Resynchronization Therapy
Key points
Introduction
Atrioventricular optimization
Interventricular optimization
Summary
References
What We Can Learn from Super-responders
Key points
Introduction
Definition of super-responders to cardiac resynchronization therapy
From bench to bedside: Cardiac resynchronization therapy and reverse remodeling
Prevalence and predictors of super-response to cardiac resynchronization therapy: Long-term prognosis
Patient selection and procedure planning
Cardiac MRI
Computed tomography
Summary
References
Cardiac Resynchronization Therapy: How to Decrease Nonresponders
Key points
Background
Criteria for response to cardiac resynchronization therapy
Factors that may improve the numbers of cardiac resynchronization therapy responders
Summary
References
Follow-up
Cardiac Resynchronization Therapy Follow-up: Role of Remote Monitoring
Key points
Introduction
Remote monitoring of implantable devices
Observational registries
Cardiac resynchronization therapy effectiveness
Randomized studies of resource use and time to clinical decision
Clinical outcome trials
Meta-analysis
Experience from tele