Drugs for the Geriatric Patient E-Book

Ronald I. Shorr

Description

This user-friendly, comprehensive drug reference, point-of-care usage -provides clinical information on more than 1000 drugs and their use in geriatric patients. In addition to dosage information and clinical indications, this reference also addresses the challenging issues of drug-drug and drug-disease interactions, polypharmacy, toxicity, compromised renal and hepatic function, withdrawal events, and more. Useful summary sections provide ‘at a glance' conclusions, recommendations and clinical pearls.

• Get comprehensive guidance on all the drugs you could conceivably encounter in treating the geriatric patient.
• Better serve your geriatric patients with dosage and usage guidelines developed specifically for them.
• Find information quickly using the practical, clinically-focused, full-color format.

Informations

• Publié par: Saunders
• Date de parution: 11 avril 2007
• Nombre de lectures: 1
• EAN13: 9781437710359
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Drugs for the Geriatric Patient

Ronald I. Shorr, M.D., M.S.
Ruth S. Jewett Professor of Geriatrics, Chief Division of Geriatric Medicine, Department of Aging and Geriatric Research, College of Medicine
Associate Director Institute on Aging, University of Florida
Director Education and Clinical Center (GRECC), Malcom Randall Veteran’s Affairs Medical Center, North Florida/South Georgia Veterans Health System Gainesville, Florida

Angela B. Hoth, PharmD
Clinical Pharmacy Specialist, VA Medical Center, Iowa City, Iowa

Nathan Rawls, PharmD
Professor Clinical Pharmacy College of Pharmacy, University of Tennessee
Clinical Pharmacy Specialist, Pharmacy Service, Veterans Affairs Medical Center, Memphis, Tennessee
W.B. Saunders
Copyright
SAUNDERS ELSEVIER
1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
Drugs for the Geriatric Patient
ISBN-13: 978-1-4160-0208-6
ISBN-10: 1-4160-0208-1
Copyright © 2007 by Saunders, an imprint of Elsevier Inc.
All rights reserved . No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier’s Health Sciences Rights Department in Philadelphia, PA, USA: phone: [phone], fax: [phone], e-mail: [e-mail] . You may also complete your request on-line via the Elsevier homepage ( www.elsevier.com ), by selecting ‘Customer Support’ and then ‘Obtaining Permissions’.


Notice
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the Publisher nor the Editors assume any liability for any injury and/or damage to persons or property arising out or related to any use of the material contained in this book.
The Publisher
Library of Congress Cataloging-in-Publication Data
Drugs for the geriatric patient/[edited by] Ronald I. Shorr, Angela B. Hoth, Nathan Rawls.
p.; cm.
Includes bibliographical references and index.
ISBN-13: 978-1-4160-0208-6
ISBN-10: 1-4160-0208-1
1. Geriatric pharmacology–Handbooks, manuals, etc. I. Shorr, Ronald I. II. Hoth, Angela B. III. Rawls, Nathan.
[DNLM: 1. Pharmaceutical Preparations–United States–Handbooks. 2. Aged–United States. 3. Drug Therapy–United States–Handbooks. QV 39 D7942 2007]
RC953.7.D795 2007
615.5’80846–dc22
2006051299
Acquisitions Editor : Rolla Couchman
Developmental Editor : Heather Krehling
Publishing Services Manager : Frank Polizzano
Design Direction : Karen O’Keefe Owens
Cover Photo by : Rebecca Brodwick
Printed in United States of America
Last digit is the print number: 9 8 7 6 5 4 2 1
Dedication
To our families, patients, students and teachers, without whom this book would not be possible.
Contribution by

Rebecca J. Beyth, M.D., M.Sc., Associate Professor and Chief Division of Career Development and Education Department of Aging and Geriatrics University of Florida, Associate Director, Rehabilitation and Outcomes Research Center NFSGVHS (ISIB), Gainesville, Florida
Introduction

Ron Shorr
Thank you for your interest in D rugs for the G eriatric P atient . We have designed this book to be used by providers of care to geriatric patients in a variety of settings. The material is accurate and easy to use. The sections are primarily self-explanatory and include such categories as brand names; a brief overview of clinical pharmacology; indications and dosages, including off-label uses in geriatric patients; and contraindications. Also included is a checklist entitled “Geriatric Side Effects at a Glance.” Not all patients suffer side effects from medications, but we have identified some common side effects that providers should be aware of. Included also is regulatory information that applies to the use of certain drugs in long-term care settings in the United Sates and Food and Drug Administration black box information.
For drugs that are “OBRA regulated in U.S. Long-Term Care,” we identified drugs that are explicitly regulated (e.g., antipsychotic agents) as well as those that are included in the interpretive guidelines for drug regimen review (e.g., drugs that are potentially inappropriate in the elderly). Interested parties should review the federal regulations for more specific information.
We hope this categorization scheme helps prescribers who are outside the United States. The patient and family education section may also be useful. For commonly used agents of special relevance to geriatric patients, we also include a narrative summary with relevant references.
Readers are encouraged to contact the editors with comments, concerns, and criticisms.

Acknowledgements
My thanks to Heather Krehling and Rolla Couchman for your patience and encouragement (and cheesesteak!)
Abbreviations

ABG arterial blood gas
ac before meals
ACE angiotensin-converting enzyme
ACT activated clotting time
ACTH adrenocorticotropic hormone
AD right ear
ADAS Alzheimer’s Disease Assessment Scale
ADH antidiuretic hormone
ADHD attention-deficit-hyperactivity disorder
ADP adenosine diphosphate
aer aerosol
AIDS acquired immunodeficiency syndrome
alk alkaline
ALS amyotrophic lateral sclerosis
ALT alanine aminotransferase, serum
AM, a.m. ante meridiem
AMD age-related macular degeneration
AMS altered mental status
ANA antinuclear antibody
ANC absolute neutrophil count
APAP acetaminophen
APL acute promyelocytic leukemia
approx. approximately
aPTT activated partial thromboplastin time
ARB angiotensin receptor blocker
ARDS adult respiratory distress syndrome
AS left ear
ASA acetylsalicylic acid
5-ASA 5-aminosalicylic acid
AST aspartate aminotransferase, serum
AT 1 angiotensin II receptor, type 1
AT II angiotensin II
ATP adenosine triphosphate
AU each ear
AUC area under curve
AV atrioventricular; arteriovenous
AZT zidovudine
BB beta-blocker, beta-blocking
bid twice a day
BP blood pressure
BPH benign prostatic hyperplasia
BSA body surface area
BUN blood urea nitrogen
BZ benzodiazepine
°C degrees Celsius (centigrade)
Ca calcium
CABG coronary artery bypass grafting
CAD coronary artery disease
cAMP cyclic adenosine monophosphate
cap capsule
cath catheterize
CBC complete blood count
cc cubic centimeter
CDC Centers for Disease Control and Prevention
CGMP cyclic guanosine monophosphate
chew tab tablet, chewable
CHF congestive heart failure
Cl chloride
cm centimeter
CML chronic myeloid leukemia
CMV cytomegalovirus
CNS central nervous system
CO 2 carbon dioxide
COMT catechol-O-methyltransferase
COPD chronic obstructive pulmonary disease
COX-2 cyclooxygenase-2
CPAP continuous positive airway pressure
CPK creatine phosphokinase
CR creatine kinase
Cr creatinine
CrCl creatinine clearance
CRF chronic renal failure
CRP c-reactive protein
CRPS complex regional pain syndrome
CSF cerebrospinal fluid
CT computer tomography
CTCL cutaneous T-cell lymphoma
CV cardiovascular
CVA cerebrovascular accident
CVD cardiovascular disease
CVP central venous pressure
CXR chest x-ray
D-C discontinue
DCIS ductal carcinoma in situ
DEA Drug Enforcement Administration
DEXA dual-energy x-ray absorptiometry
DHA docosahexaenoic acid
DHE dihydroergotamine
DHT dihydrotestoserone
DIC disseminated intravascular coagulation
dl deciliter
D L CO diffusing capacity of carbon monoxide
DMARDs disease-modifying antirheumatic drugs
DNA deoxyribonucleic acid
DOPA dihydroxyphenylalanine
DVT deep vein thrombosis
D5W 5% dextrose in water
ECG electrocardiogram
EDTA ethylenediaminetetraacetic acid
EEG electroencephalogram
EENT eye, ear, nose, throat
EGFR epidermal growth factor receptor
EIAED enzyme-inducing antiepileptic drug
ELISA enzyme-linked immunosorbent assay
elix elixir
EPA eicosapentaenoic acid
ESR erythrocyte sedimentation rate
ESRD end-stage renal disease
°F degrees Fahrenheit
FDA (U.S.) Food and Drug Administration
FEV 1 forced expiratory volume in 1 second
FSH follicle-stimulating hormone
5-FU 5-fluorouracil
g gram
GABA gamma-aminobutyric acid
GAD generalized anxiety disorder
GERD gastroesophageal reflux disease
GFR glomerular filtration rate