Endocrine Tumors, An Issue of Surgical Oncology Clinics of North America

Douglas L Fraker

Description

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Douglas L. Fraker, is devoted to Endocrine Tumors. Dr. Fraker has assembled expert authors to review the following topics: Management of thyroid nodular disease: Current cytopathology classifications and genetic testing; Surgical management of lymph node compartments in papillary thyroid cancer; Current guidelines for post-operative treatment and follow-up of well differentiated thyroid cancer; Outpatient thyroid surgery – is it safe?; Asymptomatic hyperparathyroidism- diagnostic pitfalls and surgical intervention; Intra-operative PTH monitoring: optimal utilization; Minimally invasive parathyroidectomy vs bilateral neck exploration for primary hyperparathyroidism; Pheochromocytoma and paraganglioma: Diagnosis, genetics, and treatment; Minimally invasive adrenalectomy; Treatment of adrenocortical cancinoma: benefits of aggressive surgery; Biochemical diagnosis and pre-operative imaging of gastro-intestinal neuroendocrine tumors; Minimally invasive techniques for resection of pancreatic neuroendocrine tumors; and Treatment of metastatic neuroendocrine tumors to the liver.

Sujets

• Médecine
• Spécialités médicales
• Endocrinology
• Metabolism
• Medical

Informations

• Publié par: Elsevier
• Date de parution: 19 janvier 2016
• Nombre de lectures: 0
• EAN13: 9780323414739
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Endocrine Tumors
Surgical Oncology Clinics of North America
Editor
Douglas L. Fraker, MD
Division of Endocrine Surgery and Surgical Oncology, Department of Surgery, University of Pennsylvania, Philadelphia, PA, USA
Consulting Editor
Nicholas J. Petrelli

www.surgonc.theclinics.com

Clinics Review Articles

January 2016 Volume 25 Number 1
Table of Contents
Cover image
Title page
Copyright
Contributors
Consulting Editor
Editor
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Foreword
Preface. Advances in Endocrine Surgery
Management of Thyroid Nodular Disease: Current Cytopathology Classifications and Genetic Testing
Key points
Introduction: nature of the problem
Cytopathologic classification
Molecular tests
Genetic mutations
Summary
References
Surgical Management of Lymph Node Compartments in Papillary Thyroid Cancer
Key points
Introduction
Nomenclature: prophylactic versus therapeutic
Epidemiology of central neck metastases
Controversy regarding prophylactic central neck dissection
Preoperative assessment of the cervical nodal compartments
Intraoperative assessment of lymph node status
Compartmental anatomy
Technique of central neck dissection
Technique of lateral neck dissection
Impact of nodal clearance on recurrence and survival
Recurrent nodal metastases
Summary
Acknowledgments
References
Current Guidelines for Postoperative Treatment and Follow-Up of Well-Differentiated Thyroid Cancer
Key points
Assignment of risk
The incidental papillary thyroid microcarcinoma
Completion thyroidectomy
Radioactive iodine treatment
Thyroid-stimulating hormone suppression
Postoperative adjuncts for high-risk patients
Surveillance
Treatment of recurrence
Radioactive iodine refractory disease
Summary
References
Outpatient Thyroidectomy: Is it Safe?
Key points
Background
Definition of outpatient thyroidectomy
Benefits of outpatient thyroidectomy
Risks of outpatient thyroidectomy
Appropriate patient selection for outpatient thyroidectomy
Techniques to improve success of outpatient thyroidectomy
Summary
References
Asymptomatic Primary Hyperparathyroidism: Diagnostic Pitfalls and Surgical Intervention
Key points
Introduction
Biochemical diagnosis of primary hyperparathyroidism
Considerations for differential diagnosis
Indications, risks, and benefits of parathyroidectomy for primary hyperparathyroidism
Surgical criteria for asymptomatic primary hyperparathyroidism
Summary
References
Intraoperative Parathyroid Hormone Monitoring: Optimal Utilization
Key points
Introduction
Intraoperative parathyroid hormone: historical perspective
Operative success with intraoperative parathyroid hormone monitoring
Application of intraoperative parathyroid hormone monitoring
Intraoperative parathyroid hormone sampling protocol
Intraoperative parathyroid hormone criteria for predicting operative success
Predicting recurrence with intraoperative parathyroid hormone
Cost-effectiveness of intraoperative parathyroid hormone monitoring
Summary
References
Minimally Invasive Parathyroidectomy Versus Bilateral Neck Exploration for Primary Hyperparathyroidism
Key points
Introduction
Patient evaluation
Surgical treatment options
Comparison of focused neck exploration to bilateral neck exploration
Summary
References
Pheochromocytoma and Paraganglioma: Diagnosis, Genetics, and Treatment
Key points
Introduction: nature of the problem
Epidemiology
Pathophysiology
Clinical presentation and diagnosis
Preoperative management
Surgical treatment of the primary tumor
Postoperative management, outcomes, and follow-up
Summary
References
Minimally Invasive Adrenalectomy
Key points
Introduction
Patient evaluation and indications for adrenalectomy
Metastases to the adrenal gland
Preoperative preparation
Approaches to surgery: laparoscopic transabdominal versus posterior retroperitoneoscopic adrenalectomy
Surgical technique: laparoscopic transabdominal adrenalectomy
Surgical technique: posterior retroperitoneoscopic adrenalectomy
Other approaches to adrenalectomy
Indications for open surgery
Summary
References
Surgical Management of Adrenocortical Carcinoma: An Evidence-Based Approach
Key points
Introduction
What is the appropriate diagnostic and imaging workup for patients with suspected adrenocortical carcinoma?
What are the pathologic determinants of malignancy? What factors are prognostic in resected adrenocortical carcinoma?
What are the principles of surgical and perioperative management for primary tumors? How should patients who have undergone resection be surveilled?
Is there benefit to routine en bloc resection of adjacent organs or aggressive regional lymphadenectomy?
Is there evidence to support minimally invasive resection for known or suspected malignancy?
Is there a role for an aggressive surgical approach in locally recurrent or metastatic disease?
What are the current and emerging options for multimodality management of adrenocortical carcinoma?
Proposed approach to the multimodal management of localized adrenocortical carcinoma
Summary
References
Biochemical Diagnosis and Preoperative Imaging of Gastroenteropancreatic Neuroendocrine Tumors
Key points
Introduction
Biochemical markers for gastroenteropancreatic neuroendocrine tumors
Laboratory tests and biomarkers for gastrointestinal neuroendocrine tumors
Current recommendations for biochemical testing in gastrointestinal neuroendocrine tumors
Current recommendations for biochemical testing in pancreatic neuroendocrine tumors
Biomolecular diagnostics in neuroendocrine tumors
Imaging tests for diagnosis and staging of gastroentericpancreatic neuroendocrine tumors
Summary
References
Minimally Invasive Techniques for Resection of Pancreatic Neuroendocrine Tumors
Key points
Introduction
Diagnosis
Preoperative evaluation
Surgical technique
Outcomes
Summary
References
Treatment of Neuroendocrine Liver Metastases
Key points
Introduction: nature of the problem
Treatment options: liver resection and debulking
Liver resection and debulking: review of the literature
Treatment options: radiofrequency ablation
Surgical technique
Treatment options: intra-arterial therapies
Summary
References
Copyright
ELSEVIER
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SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA Volume 25, Number 1
January 2016 ISSN 1055-3207, ISBN-13: 978-0-323-41472-2
Editor: John Vassallo
Developmental Editor: Meredith Clinton
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